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Reverse metabolic syndrome in 12 weeks by eating more calories from almonds
Reproduced from original article:
https://www.naturalhealth365.com/here-is-how-eating-more-calories-can-reverse-metabolic-syndrome-in-12-weeks.html
by: June 18, 2025
(NaturalHealth365) What if reversing metabolic syndrome was as simple as reaching for the right snack? Scientists at Oregon State University have recently demonstrated that consuming a handful of almonds daily can significantly improve your health in ways that should prompt every doctor to reconsider their treatment approach.
Published in Nutrition Research, this 12-week study tracked people with metabolic syndrome and discovered something remarkable: those who ate just 2 ounces of almonds daily – about 45 nuts – showed dramatic improvements in cholesterol levels, waist circumference, and gut inflammation.
This matters because metabolic syndrome affects nearly 40% of American adults and makes them three times more likely to suffer heart attacks or strokes.
What happened when scientists fed people more calories
The Oregon State researchers split 77 people aged 35-60 with diagnosed metabolic syndrome into two groups. One group ate 320 calories worth of almonds daily. The control group ate crackers with identical calories but lacking the healthy fats, protein, and micronutrients found in almonds.
After just 12 weeks, the almond group showed:
Cardiovascular improvements:
- Significant decreases in total cholesterol
- Major reductions in LDL cholesterol
- Noticeable waist circumference reduction
Gut health benefits:
- Dramatic improvements in intestinal inflammation markers
- Better gut barrier function in participants with baseline inflammation
- Reduced inflammatory compounds like calprotectin and myeloperoxidase
Nutritional transformation:
- Marked increases in vitamin E levels
- Enhanced intake of magnesium, copper, biotin, and healthy fats
- Better overall nutrient status across multiple categories
What 9 out of 10 Americans don’t get enough of
Here’s something shocking: More than 90% of Americans don’t get enough vitamin E, a nutrient crucial for heart health, nerve function, and blood clotting regulation. Just one ounce of almonds provides 50% of daily vitamin E needs – the highest amount in any tree nut.
“Even factoring in those who take supplements, vitamin E remains a nutrient of concern in the U.S.,” notes co-author Maret Traber. “Consuming almonds could help fill this gap.”
The study participants showed improved vitamin E-to-cholesterol ratios within weeks, indicating better cardiovascular protection at the cellular level.
Why almonds work so well
Lead researcher Laura Beaver explains: “The changes in cholesterol levels suggest that a metabolic shift occurred in people who snacked on almonds daily.” This isn’t just about individual nutrients – it’s almonds’ unique combination working synergistically:
- Healthy fats improve lipid metabolism
- Fiber and polyphenols support gut barrier function
- Protein provides satiety without weight gain
- Concentrated micronutrients fill critical gaps that most people don’t even know they have
Participants managed to add 320 calories daily without packing on pounds. How? Almonds’ protein and fiber kept them satisfied longer, naturally crowding out cravings for junk food.
Other natural solutions to combat metabolic syndrome
Almonds aren’t the only game-changer. Several other natural approaches have demolished metabolic syndrome in clinical trials:
Chromium and magnesium: Chromium picolinate (200-400 mcg daily) helps cells effectively use insulin, while magnesium (400-600 mg daily) can help lower blood pressure and inflammation levels.
Intermittent fasting: The simple 16:8 eating window has been shown to reverse insulin resistance and shrink waistlines in multiple studies. People often see changes in cholesterol within 2-3 months.
Green Tea Extract: EGCG extract (400-500 mg daily) specifically targets belly fat while improving how cells respond to insulin. It even helps clear fat from the liver.
Berberine: Berberine works just as well as the diabetes drug metformin for blood sugar control, and also improves cholesterol levels and reduces inflammation. Most people take 500 mg twice daily.
Quick HIIT sessions: Just 15-20 minutes of high-intensity intervals three times a week can help reverse insulin resistance and improve every metabolic marker within three months.
Why food beats pills every time
This almond research upends Western medicine. Instead of masking symptoms with drugs, we’re seeing real root-cause healing through nutrition.
Dr. Emily Ho puts it perfectly: “Unless there is concern about nut allergies, it’s easy to recommend a handful or two of almonds as a healthy snack, especially for people concerned about their metabolic disease risk.”
Think about it – 45 almonds cost less than a typical supplement, need no prescription, and deliver benefits that extend way beyond metabolic syndrome. Additionally, people noticed real changes within weeks simply by swapping their usual snacks.
The bigger picture beyond almonds
Here’s what gets exciting: almonds work best as part of a complete strategy. Getting nutrients from whole foods creates effects you can’t replicate with just isolated supplements.
The nutrients in almonds work together synergistically, acting as a team. This same principle applies to other whole foods and lifestyle changes that target multiple metabolic pathways simultaneously.
For anyone dealing with metabolic syndrome, this research proves you don’t have to accept declining health or rely solely on medications with side effects. Simple, sustainable changes can create real improvements.
The key is consistency and combining approaches that make sense together. Your body responds better to comprehensive support than isolated interventions. If you’re ready to discover comprehensive strategies for cardiovascular health that go beyond simple dietary changes, the Cardiovascular Docu-Class features 22 leading experts who reveal advanced approaches to reversing heart disease, clearing arterial plaque, and optimizing circulation naturally, including the latest research on how nutrition directly impacts cardiovascular function.
Your heart doesn’t have to settle for gradual decline. Sometimes the most powerful healing comes in small, consistent amounts.
Sources for this article include:
Little-Known Spice Helps Control Appetite and Burn Calories
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2023/08/28/spice-control-appetite-and-burn-calories.aspx
The original Mercola article may not remain on the original site, but I will endeavor to keep it on this site as long as I deem it to be appropriate.
Analysis by Dr. Joseph Mercola Fact Checked August 28, 2023
STORY AT-A-GLANCE
- Cardamom, a popular spice in Indian and Middle Eastern foods, helped maintain lean body mass and reduced fat in an animal study, while the animals in the intervention group ate more than the control group
- Obesity is at epidemic proportions, fueled in large part by addictive processed foods that destroy your metabolism and override your intrinsic intake regulation
- Chewing on cardamom seeds has a long history of being used to freshen breath. Research shows a cardamom seed extract is effective against oral bacteria that produce bad breath and oral infections
- Cardamom is a natural way of boosting your natural killer cells. It is responsible for boosting your immune system to fight against viral infections and has demonstrated antineoplastic properties against triple negative breast cancer and colon cancer
For the better part of three centuries, the U.S. has been a meat and potato nation. This is slowly changing as more people are choosing authentic Middle Eastern, Indian or Thai cuisine. Cardamom is a spice recognized as important in ancient cooking that originated in tropical parts of India, Nepal, South Asia and the Middle East.
Cardamom is known as one of the most expensive spices in the world,1 costing roughly $30 a pound, slightly less than vanilla, which can cost $50, and significantly less than saffron, which can command up to $5,000 per pound.
Researchers have discovered yet another health benefit from cardamom’s antioxidant-packed seed pod — it reduces inflammation, increases appetite and increases calorie burn at the same time.2
Cardamom has a very strong flavor profile that can turn an ordinary dish into something special. There are two broad types of cardamom. Green cardamom has a flavor that goes well with sweet and savory dishes, while black cardamom has a more minty and smokier flavor. Green cardamom is known as true cardamom, and is the common variety found at the grocery store.
The spice is made from the seed pods. In Indian recipes, whole pods are used while preparing a variety of curries and rice, while in Middle Eastern cooking, ground cardamom is used in certain desserts and foods.
While you can get powdered cardamom at the grocery, your food will have more flavor when you start with the pods. Green cardamom can also be used in coffee by simply grinding a few seeds along with coffee beans.
The Relationship: Cardamom, Calories and Weight Loss
The 2023 animal study3 was published in the International Journal of Molecular Science by researchers from Texas A&M who found a range of health benefits from consuming cardamom. The principal investigator, Luis Cisneros-Zevallos, Ph.D., is a horticulture and food science professor from Texas A&M College of Agriculture and Life Sciences.
The study demonstrated that cardamom may help maintain lean body weight while reducing body fat.4 The data showed cardamom modulates the neuroendocrine axis which regulates body weight, mitochondrial activity, food intake and energy expenditure.
Intake increased fat breakdown in subcutaneous adipose tissue and fasting fat oxidation, and demonstrated it could modulate appetite leading to an increase in energy expenditure all while lowering body fat mass. Interestingly, the appetite modulation led to an increase in appetite, while the mice maintained body weight and lost body fat.
The dosage was extrapolated to human intake, giving a conversion of 76.9 mg to 308.4 mg of bioactive cardamom for an adult weighing 60 kilograms (132.277 pounds).
“Our team has discovered an amazing opportunity to utilize cardamom as a promoter of overall health,” Cisneros-Zevallos said. “Cardamom seeds, with this new functionality, can be used in different industries, including the sports industry, functional foods and dietary supplements to favor the production of healthier foods.”5
In addition to the health benefits, cardamom is economically important to Guatemalan farmers, of whom there are “more than 350,000 currently practicing sustainable and environmental cardamom shade farming in the tropical forest.”6
Cisneros-Zevallos believes there’s a wide range of potential us e in addition to the economic importance in Guatemala. Expanding cardamom use could provide economic stability and help address “the immigration crisis observed in recent years.”7
Junk Food Increases Hunger and Overeating
Obesity and overweight are at epidemic proportions. When a person’s weight is higher than normal weight for a given height, the National Institute of Diabetes and Digestive and Kidney Diseases8 describes the condition as being overweight or obese. According to data collected from 2017-2018, 30.7% of all men and women were overweight and 42.4% were obese.
The percentage of women with severe obesity is higher than the percentage of men with severe obesity. A significant risk factor for overweight and obesity is junk food. In the featured study, the mice who ate diets containing cardamom consumed more food but gained less weight than the control group that did not eat cardamom.
The food industry has become notorious for funding anti-obesity programs focusing on physical activity, yet research clearly shows that processed foods, sugary beverages and high carbohydrate diets are a primary concern for weight gain. Inactivity certainly contributes to the problem, but you cannot exercise your way out of a poor diet.
In addition to junk food destroying your metabolism and promoting obesity, studies have also demonstrated that processed foods are addictive. Manufacturers have figured out a way to override your intrinsic regulators by engineering processed foods that are hyper-rewarding.
In a 2013 New York Times article,9 investigative reporter Michael Moss described this as “the tendency for big, distinct flavors to overwhelm your brain.” The greatest successes, whether beverages or foods, owe their “craveability” to complex formulas that pique your taste buds without overwhelming them, thereby overriding your brain’s satiety signals.
While cardamom may help your body to burn more fat and retain more lean muscle mass, it is also important to note that the mice in the study were fed a normal diet. In other words, they were not eating higher amounts of junk food while losing fat and retaining muscle.
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Chewing Cardamom Helps Teeth, Breath and Smoking Cessation
Cardamom has a long history of medicinal uses, including dental health and smoking cessation. There’s evidence of traditional use for dental health that goes back thousands of years. Chewing the seeds is endorsed by a study10 from India as a breath freshener that also stimulates saliva secretions.
Cardamom is often referred to as the queen of spices because of the pleasant aroma and has been common in the Indian subcontinent as a folk remedy. The researchers wrote:11
“But the most common use of cardamom in India has been as an excellent breath freshener. It is a common sight to see women folk as well as men popping cardamom pods to make their breath not minty fresh but “cardamom fresh”.”
Extract from the cardamom seed is also effective against oral bacteria. A dentistry paper12 on oral bacteria notes “The oil extracted from cardamom seeds is a combination of terpene, esters, flavonoids and other compounds. Cineole, the major active component of cardamom oil, is a potent antiseptic that is known to kill bacteria producing bad breath and other infections.”
Additionally, research has found that chewing gum may help lessen the symptoms of nicotine withdrawal. One study13 tested peppermint, vanilla and baked apple cardamom flavored gums against each other and a control group that did not chew gum.
Those who chewed gum exhibited lower levels of tension and anxiety. Those chewing the vanilla and baked apple cardamom flavored gums had lower levels of negative nicotine withdrawal symptoms than those chewing the peppermint gum. The findings suggest that certain flavors, such as cardamom, could lower challenges with nicotine withdrawal.
Remarkable Ability to Enhance Natural Killer Cells
Natural killer cells are a specific type of white blood cell that’s an important component in your innate immune system. They’re involved in viral disease and other diseases such as cancer and autoimmune conditions. Natural killer cells can kill cells but are not antigens-specific. In other words, they help contain an infection as your adaptive humoral immune response generates T-cells to clear the infection.
Researchers have made an interesting discovery: With enough natural killer cells in your system, you do not contract influenza.14 Natural killer cells may help prevent some infections. One way of naturally boosting your natural killer cells is to ingest cardamom.
Cardamom is known for its immune-boosting benefits, including increasing natural killer cell activity.15 Researchers wrote, “Remarkably, it is evident that black pepper and cardamom extracts significantly enhance the cytotoxic activity of natural killer cells, indicating their potential anti-cancer effects.”16
A 2007 study17 found cardamom could inhibit colon cancer by preventing cellular damage caused by the accumulation of toxins and various waste products in the colon. Researchers also believe that cardamonin could have therapeutic potential against triple negative breast cancer.18
Cardamonin is a natural compound found in cardamom that demonstrated the ability to target a gene that promotes cancer cell evasion of the immune system. Roughly 10% to 15% of all breast cancers are categorized as triple-negative, which means they lack specific receptors for progesterone and estrogen and do not have excess amounts of HER2 protein.
These characteristics increase the difficulty in treating cancer cells. Patricia Mendonca, Ph.D., assistant professor and research analyst at Florida A&M University in Tallahassee, commented in a press release:19
“This is the first study to describe cardamonin’s inhibitory effect on the expression of PD-L1, which is relevant for the treatment of triple-negative breast cancer. These findings add support to other research that has shown differences in the tumor microenvironment between African and non-African Americans.”
Other ways you can enhance your natural killer cells are to get regular exercise, quit smoking and add black pepper to your food. Like cardamom, black pepper has been shown to enhance the cytotoxic activity of NK cells and promote healthy immune function.20 You’ll find more ways to boost your natural killer cells and support your innate immunity in my article, “How to Improve Your Immune Function.”
- 1 Money Inc, April 14, 2023
- 2, 4, 5, 6, 7 News-Medical, April 13, 2023
- 3 International Journal of Molecular Science, 2023;24(4)
- 8 National Institute of Diabetes and Digestive and Kidney Diseases, Overweight and Obesity Statistics
- 9 New York Times, February 20, 2013
- 10, 11, 12 Dental Research Journal, 2012; 9(2)
- 13 Addictive Behavior, 2010; 35 (11)
- 14 EurekAlert!, June 13, 2018
- 15, 16, 20 Journal of Medicinal Food, 2010;13(2)
- 17 Asian Pacific Journal of Cancer Prevention, 2007;8(4)
- 18, 19 NewsWise, March 25, 2022
Why Standing May Be as Important as Exercise
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2022/08/19/standing-benefits.aspx
The original Mercola article may not remain on the original site, but I will endeavor to keep it on this site as long as I deem it to be appropriate, and will not be bullied into removing it.
Analysis by Dr. Joseph Mercola Fact Checked August 19, 2022

STORY AT-A-GLANCE
- Sitting and other forms of prolonged, uninterrupted sedentary time promotes cardiometabolic disorders, obesity, depression and all-cause mortality in adults and in children are linked to obesity, anxiety and depressive symptoms
- More than two dozen chronic diseases, from diabetes and high blood pressure to back pain and deep vein thrombosis, have been linked to excessive sitting
- Children at standing desks burn 15% to 25% more calories during the school day than those who remain sitting; students were also less likely to report neck and shoulder discomfort when using standing desks
- In the workplace, standing desks have also been found to trigger increased brain activity and do not hinder cognitive performance as has been suggested
- If you want to take your fitness to the next level, make standing a workout of its own by standing on a wobble board at your standing desk
During the pandemic, the already largely sedentary American population moved even less, with daily steps plunging by an average of 20%.1 With more people working from home, the tendency to sit at a computer for long hours is taking a toll on both physical and mental health, but the upside is that many are increasingly realizing the important of daily movement.
While regular physical exercise is important, so, too, is doing virtually anything other than sitting — even standing. This is why many fitness trackers have goal settings for not only calories burned and steps taken in a day, but also reaching a standing-time goal.2
What Sitting Does to Your Body
Sitting is a behavior with a very low energy expenditure that’s associated with poor health outcomes in both adults in children. Sitting and other forms of prolonged, uninterrupted sedentary time promote cardiometabolic disorders, obesity, depression and all-cause mortality in adults and in children is linked to obesity, anxiety and depressive symptoms.3
Increased musculoskeletal symptoms are also associated with prolonged sitting,4 and being sedentary for long periods of time each day even appears to accelerate aging at the cellular level.
Among close to 1,500 older women included in one study, those who sat the longest were, on average, eight years older, biologically speaking, than women who moved around more often, with researchers concluding, “avoidance of a highly inactive lifestyle may provide health benefits at the cellular level.”5
Another study found that excessive sitting increases lung cancer risk by 54%, uterine cancer risk by 66% and colon cancer risk by 30%, with researchers noting:6
“Sedentary behavior contributes to an interrelated network of increased body fat, altered production of sex hormones, metabolic dysfunction, leptin, adiponectin and inflammation, encouraging cancer development.”
Separate research, published in the American Journal of Preventive Medicine, further found that sitting for more than three hours a day causes 3.8% of all-cause deaths in the 54 countries surveyed.7
Cutting your sitting time to less than three hours a day could increase your life expectancy by 0.2 years (about 2.4 months), the researchers concluded. More than 60% of people globally spend more than three hours a day sitting.8
Why You Should Break Free From ‘Chair Addiction’
“Chair addiction has become a hallmark of modernity,” according to Dr. James Levine, author of the book “Get Up!: Why Your Chair Is Killing You and What You Can Do About It,” and the inventor of the treadmill desk.9 “Sitting kills more people than smoking because more people sit excessively than smoke, and the health sequelae of sitting are more numerous,” he added.10
More than two dozen chronic diseases, from diabetes and high blood pressure to back pain and deep vein thrombosis, have been linked to excessive sitting, and fitting in an exercise session isn’t likely to offset excessive sitting’s harmful effects.11
It was during the Industrial Revolution, when people moved from agricultural communities to cities, that sedentary behaviors and many of their related health problems became common. Levine wrote in Mayo Clinic Proceedings:12
“Once the Industrial Revolution took hold, lethal sitting became inevitable. In the 1800s, factory production lines were invented to diminish the need for a worker to waste time walking. Soon after that, modern offices were developed with the premise that the fewer minutes workers moved during the workday, the less time was wasted.
The 1930s saw the rise of the archenemy — the office chair. Workplace automation and mechanization followed with the introduction of typewriters, Dictaphones, intercoms, and adding machines — all of which diminished movement. By the 1950s, mass-produced and affordable cars came onto the market and people forewent walking to work and drove.
Last came desk-based computerization and the conversion of active play to electronic play. It took nature 2 million years to design the walking, dynamic human, and it took those humans 200 years to reverse the art of nature and cram people all day long into chairs … The human genome has not substantially changed in 200 years, but over that time the humans’ default posture has changed from ambulatory to chair-based.”
Standing Benefits Mind and Body
One of the most obvious benefits of standing is that it increases energy expenditure, or calories burned, which can help to ward off obesity. Sitting increases metabolic rate by only 5% compared to lying down, but walking, even at a slow pace, increases energy expenditure 100%.13
According to Stand Up Kids, an organization whose mission is to bring a standing desk to every public school child within 10 years, children at standing desks burn 15% to 25% more calories during the school day than those who remain sitting — and the difference was even greater among children with obesity, who burned 25% to 35% more calories at standing desks.14
When standing desks were introduced to a fourth grade classroom at one school, standing time increased by 17 to 26 minutes per school day while sitting time decreased by 17 to 40 minutes.15 The students were also less likely to report neck and shoulder discomfort when using standing desks.
A study published in the Journal of Medicine and Sport also revealed that in first grade boys, lower levels of physical activity and higher levels of sitting time were linked to poorer reading skills.16
In the workplace, standing desks trigger increased brain activity and do not hinder cognitive performance as has been suggested.17 Other benefits of standing, reported by Stand Up Kids, include:18
- Prevention of the body’s tissue adaptation to static positions, such as short hip flexors and hamstrings, rounded upper back and poor shoulder position
- Prevention of orthopedic degradation and dysfunction, including back and neck pain, repetitive stress injuries, pelvic floor dysfunction and knee and hip disorders
- Increased creativity and educational test scores
- Increased engagement and active learning in the classroom
How to Gradually Break Free From Your Chair
Kelly and Juliet Starrett are the husband-and-wife team who founded Stand Up Kids. Kelly has a Ph.D. in physical therapy and is the author of “Deskbound: Standing Up to a Sitting World.” He is one of the leaders in the CrossFit movement and stresses the importance of proper body mechanics, both in and outside the gym.
His first book, “Becoming a Supple Leopard,” addresses biomechanical inadequacies that might increase your risk of injury. Juliet is a former competitive athlete, CrossFit authority and co-founder of the healthy movement website Mobility WOD. In 2016, I interviewed Kelly about his book, “Deskbound,” which helped me address some of my own movement challenges and is an eye-opening read about why standing is a simple way to radically improve your health.
If you’re not convinced, Kelly mentioned a study that found office workers who smoked to be healthier than nonsmokers simply because they got up every 30 minutes or so and walked outside to have a cigarette.19 “That activity was enough to be a considerable change in the function and health of the human being,” he said.
However, if you’re used to sitting for hours a day, be prepared for a gradual transition and avoid trying to switch to a standing desk “cold turkey.” The Starretts recommend first transitioning to a standing desk with a perching stool and sitting on that for 20 or 30 minutes, then gradually increasing your time.20
In addition, be sure your desk is adjusted to the proper height. Also, many people feel more comfortable having somewhere to put a foot on and off, such as a stepstool.
If you don’t have a standing desk, it’s possible to fashion one out of a regular desk by propping up your computer on a box or an overturned wastebasket. Or, if you have an island or breakfast bar in your kitchen, use that. If standing isn’t an option, you can reap many similar benefits by getting up from your chair every 20 minutes and taking a two-minute walk. For times when you do sit, “sit with skill,” the Starretts said.
They advise sitting on your sit bones, engaging your legs and trying to look over the chair. When you’re first starting out, divide your day into optional sitting and nonoptional sitting. Don’t worry about the times when you have to sit, but take stock of what they call “junk sitting” and try to whittle that down.
Try a Wobble Board While Standing
Standing is classified as a light-intensity activity when it’s “active” rather than “passive.”21 Active standing might include standing while doing dishes whereas passive standing is waiting in a line. If you want to take your fitness to the next level, make standing a workout of its own by standing on a wobble board at your standing desk.
This has added benefits for improving balance and posture while working your core muscles and boosting coordination. Beyond this, a transition to more active schools and offices, which promote not only standing but also more daily movement, could have far-reaching public health benefits, according to Levine.
“Offices can incentivize protocols for walking meetings, incentivize leg-based interactions (eg, walk across the office versus e-mail), and install walking tracks or treadmill desks. Active offices not only report improved health but less perceived stress and improved productivity.
Schools can be designed to promote active learning, and research demonstrates improvement to health, attentiveness, and educational outcomes. Bright, clean, attractive stairwells with visible prompts promote walking up steps better than do poorly lighted, dirty, dank ones.”22
The more you try to incorporate standing and movement into your day, gradually you’ll get used to the idea of standing and will find that you don’t automatically look for a chair the way you used to. You’ll be surprised by how many opportunities you have to move in a day if you start opening your eyes to them.
– Sources and References
- 1, 2 The Atlantic June 1, 2022
- 3, 4, 15 Int J Environ Res Public Health. 2019 Oct; 16(19): 3590
- 5 American Journal of Epidemiology January 18, 2017
- 6 BMJ January 21, 2015
- 7 American Journal of Preventive Medicine March 2016
- 8 The New York Times March 29, 2016
- 9, 10, 11, 12, 13, 22 Mayo Clinic Proceedings August 1, 2014
- 14, 18 Stand Up Kids, Standing vs. Sitting
- 16 Journal of Science and Medicine in Sport November 23, 2016
- 17 Hum Factors. 2020 Jun;62(4):603-612. doi: 10.1177/0018720819879310. Epub 2019 Oct 8
- 19, 20 Dan’s Plan January 6, 2017
- 21 Int J Environ Res Public Health. 2021 Aug; 18(16): 8460