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Posted by: | Posted on: November 30, 2025

This Savory Herb Helps Relieve Muscle Cramps and Improve Digestion Naturally


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/11/28/dill-muscle-cramps-digestion.aspx

Analysis by Dr. Joseph Mercola     November 28, 202

dill muscle cramps digestion

Story at-a-glance

  • Dill is a powerful herb rich in antioxidants, vitamins, and minerals that help ease muscle cramps, improve digestion, and support heart health
  • Flavonoids in dill protect your muscles and blood vessels from oxidative stress, helping you stay strong, active, and mentally sharp as you age
  • Drinking dill tea or adding fresh dill to meals calms digestive discomfort, reduces bloating, and promotes smoother digestion
  • Research shows dill helps balance blood sugar and hormones, easing menstrual cramps and supporting steady energy throughout the day
  • Using dill regularly in food or drinks fights inflammation and provides everyday support for muscle recovery and circulation

Used for centuries in kitchens and traditional medicine alike, dill has quietly earned its place as one of nature’s most functional herbs. Its delicate flavor hides a powerful secret: inside those feathery leaves is a mix of nutrients and plant compounds that work in harmony with your body’s natural systems. Modern researchers are now rediscovering what ancient cultures seemed to understand instinctively — that dill supports vitality from the inside out.

Far more than a garnish, dill’s unique chemistry supports your body’s ability to repair, recover, and maintain balance. It interacts with the muscles that keep you moving, the heart that keeps blood flowing, and the digestive system that fuels your energy. Even a small serving offers meaningful nutrition, helping your body perform better under stress, recover faster after activity, and feel more resilient overall.

As scientists continue exploring how traditional foods contribute to long-term health, dill stands out as an herb that bridges old wisdom with modern understanding. Its story isn’t just about flavor — it’s about restoring strength, calm, and balance where your body needs it most.

Dill’s Flavonoids Strengthen Muscles, Calm Inflammation, and Support Heart Health

A report in The Independent revealed that dill is packed with flavonoids — plant-based compounds that fight inflammation, oxidative stress, and the breakdown of tissues.1 These antioxidants are directly linked to slower aging, stronger muscles, and sharper cognition. Researcher Aedin Cassidy from Queen’s University Belfast explained that flavonoids help preserve skeletal muscle mass and protect against frailty, keeping you active and mentally sharp longer into life.

• Flavonoids fight oxidative stress, the hidden cause of many age-related issues — Oxidative stress refers to an imbalance between harmful molecules called free radicals and your body’s ability to neutralize them. When that balance tips, damage occurs inside your cells, speeding up aging and inflammation.

Dill’s flavonoids reduce this stress, helping your blood vessels stay flexible and your tissues resilient. Eating dill supports the “maintenance crew” that keeps your cells functioning smoothly. This process plays a key role in preventing frailty and preserving both physical and mental health.

• A tablespoon of dill delivers a meaningful nutrient punch — Fresh dill is loaded with vitamin A for vision, vitamin C for immune strength, and minerals like calcium and potassium that regulate blood pressure. These nutrients work synergistically, meaning they enhance each other’s effects. Calcium helps muscles contract properly, potassium balances fluids and supports nerve signals, and vitamin C repairs tissues after exercise or daily wear.

• Dill’s natural diuretic properties reduce swelling and fluid retention — Ancient Egyptians once used dill as a diuretic, and modern science confirms this use. A diuretic is any substance that helps your body release excess water and salt through urine. By doing so, dill helps prevent bloating, water retention, and strain on your kidneys. This process also helps manage blood pressure naturally, without harsh synthetic diuretics.

• Pickle juice flavored with dill helps athletes recover faster — One of dill’s most surprising modern uses is in post-exercise recovery. According to dietitian Beth Czerwony, people who experience muscle cramps often find relief after a small shot of pickle juice. The sodium and vitamin K in fermented pickles help replenish electrolytes lost through sweat.

Electrolytes are minerals that carry electrical charges in your body and are necessary for proper muscle contraction. When you sweat heavily, those minerals — especially sodium and potassium — drop, triggering cramps. Dill-infused pickle juice restores that balance quickly and naturally.

Dill Balances Blood Sugar and Eases Hormonal Pain

Dill’s compounds support both metabolic and hormonal balance.2 While dill’s antioxidants protect your cells from damage caused by toxins and aging, its compounds also influence the way your body regulates fat and glucose metabolism, which is important for maintaining healthy blood sugar.

• Studies show improved insulin function — In one study, adults with Type 2 diabetes were given 3 grams of dill powder daily. Within weeks, participants saw reductions in fasting insulin levels.3 Their HDL (“good”) cholesterol also increased.

These changes are signs of improved metabolic efficiency — your body’s ability to convert food into usable energy without overworking your pancreas or liver. Dill even affects specific genes responsible for regulating how your body handles sugar and fat.4 This means the herb doesn’t just mask symptoms — it influences the pathways that control how your cells use and store energy.

• The benefits extend to hormone-related issues like menstrual and labor pain — A Health article highlighted studies showing dill’s effectiveness in reducing pain during menstruation and childbirth.5 One trial found that dill powder worked as effectively as a nonsteroidal anti-inflammatory drug (NSAID) called mefenamic acid — a medication commonly used to relieve period pain.6 NSAIDs block the production of prostaglandins, which are chemicals that cause inflammation and cramps.

Dill seems to achieve similar results naturally, without the side effects often seen with synthetic painkillers. Another study compared dill seed extract to oxytocin, a hormone that promotes uterine contractions during labor.7 Women who received dill seed tea reported shorter labor times and less anxiety, suggesting it helped the body relax while still supporting natural contractions.

• Fresh dill offers daily support for digestion — Even small amounts of fresh dill in your meals contribute to overall well-being. It aids digestion by stimulating bile production, the fluid that breaks down fats in your small intestine. For anyone dealing with bloating or sluggish digestion, adding dill to your salads, soups, or meat dishes offers an easy way to improve comfort and nutrient absorption.

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Dill Calms Your Gut, Boosts Immunity, and Reduces Pain Naturally

According to an article from Tua Saúde, dill’s oils relax the smooth muscles that line your digestive tract.8 When these muscles tighten, they cause cramps, gas, or constipation. By soothing them, dill helps your digestive system move more easily and comfortably.

The article also noted that dill tea has been traditionally used to relieve infant colic — a condition marked by intense crying and gas pain in babies — because of its calming effect on the intestines. Adults benefit similarly: a warm cup of dill tea after a heavy meal helps reduce stomach pressure, relieve gas, and promote smoother digestion. This makes dill a simple, inexpensive remedy for those dealing with occasional bloating or sluggish digestion.

• Mental focus, relaxation, and better sleep are additional bonuses of dill’s natural compounds — Dill’s relaxing properties make it useful for people dealing with anxiety, restlessness, or insomnia. Stress often affects digestion, leading to discomfort and poor sleep, but dill addresses both the mind and body simultaneously. The herb’s mild sedative effect helps your nervous system unwind without causing drowsiness.

If you struggle to “shut off” your mind at night, sipping dill tea before bed or adding fresh dill to dinner helps support a more restful sleep and a calmer mood. This dual action — relaxing both your gut and brain — shows why dill has long been valued in traditional medicine systems.

• Dill’s pain-relieving and anti-inflammatory compounds work much like natural painkillers — Dill’s volatile oils — aromatic compounds found in its leaves and seeds — act as natural antispasmodics. This means they reduce muscle tension and spasms throughout your body, not just in your digestive tract. These same compounds also have analgesic properties, meaning they ease pain directly.

People with arthritis, muscle soreness, or even ear pain could experience relief from using dill tea or oil compresses. The anti-inflammatory activity reduces swelling and stiffness, helping your body recover faster after physical exertion or minor injury. Unlike over-the-counter painkillers, dill supports healing while soothing discomfort, making it a useful addition to your kitchen or home first-aid routine.

• Its antibacterial and antifungal abilities strengthen your body’s defenses against infection — Dill is a natural antimicrobial, meaning it fights harmful bacteria and fungi. Specifically, dill extracts have shown activity against Candida species, a common yeast responsible for infections in the mouth, digestive tract, and genital area.9

This property makes dill a useful ally for maintaining gut balance and preventing fungal overgrowth. Its compounds also inhibit the formation of malignant cells, indicating antitumor potential.10 While these effects need more human research, they demonstrate dill’s impressive range of protective actions.

How to Get the Most Out of Dill for Muscle, Heart, and Digestive Health

When it comes to herbs that truly work with your body — not against it — dill deserves a permanent spot in your kitchen. Its nutrients, oils, and antioxidants address the root causes of muscle cramps, inflammation, and sluggish digestion. By strengthening circulation, calming your gut, and supporting hydration, dill gives your body what it needs to perform better every day.

Whether you’re an athlete, someone with digestive issues, or simply want to age stronger, these practical tips will help you weave dill into your daily routine. Pair it with a foundation of regular movement, restorative sleep, whole-food meals, and daily sunlight to create a lifestyle that supports lasting energy and resilience.

1. Blend it into your breakfast for an easy daily start — Add a tablespoon of chopped fresh dill to your morning eggs. The flavor pairs beautifully with pastured eggs or grass fed goat cheese and gives you a morning dose of antioxidants to support circulation and muscle recovery. You can also toss dill into your morning smoothie — just a few sprigs add brightness and a gentle detoxifying effect that supports digestion after sleep.

2. Infuse your hydration with dill’s electrolytes — Instead of reaching for sports drinks, make your own electrolyte refresher: mix filtered water with a teaspoon of dill pickle brine and a squeeze of lemon. The natural sodium, potassium, and vitamin K help balance hydration and muscle function, especially after exercise or time in the heat.

For a caffeine-free afternoon lift, try dill tea — steep a few sprigs or a teaspoon of dried dill in hot water for 10 minutes. The gentle aroma promotes calm while supporting digestion and circulation.

3. Make dill a staple seasoning in your lunches and dinners — Use fresh dill as a finishing touch on grass fed meat, roasted vegetables, or soups. Mix it into raw yogurt-based dressings or homemade tzatziki for a refreshing, anti-inflammatory boost.

You’ll not only elevate flavor but also strengthen your heart and immune system through the plant compounds that protect your blood vessels from oxidative stress. Consistent use, even in small amounts, creates cumulative benefits that help your body handle physical and emotional stress more efficiently.

4. Create a simple digestion and cramp-relief ritual — When bloating or digestive trouble strikes, optimizing mitochondrial health and energy production is key to improving your gut health. However, steeping a tablespoon of fresh or dried dill in boiling water and sipping it slowly after meals provides some relief. This helps relax your intestinal muscles that cause gas and discomfort.

If you deal with frequent muscle cramps — whether from exercise or hormone cycles — combine dill with magnesium supplementation or magnesium-rich foods like spinach or dark chocolate. The synergy between dill’s natural oils and these minerals helps muscles relax and recover faster.

5. Preserve and store dill so you always have it ready — Fresh dill wilts quickly, so store it upright in a jar of water in the fridge with a loose plastic covering to keep it crisp for up to a week. You can also chop and freeze it in water using an ice cube tray, creating ready-to-use flavor cubes for soups, stews, or sautés. Keeping it visible and easy to grab increases your chances of using it consistently — a small psychological trick that makes healthy habits stick.

Think of dill as your daily green ally for stronger muscles, a calmer gut, and a steadier heart. By making it part of your meals and hydration habits, you’re not just seasoning your food — you’re feeding your body the tools it needs to stay strong, balanced, and energized.

Frequently Asked Questions About Dill

Q: What are the main health benefits of dill?

A: Dill supports muscle, heart, and digestive health through its unique mix of antioxidants, minerals, and essential oils. It helps reduce inflammation, supports electrolyte balance, eases muscle cramps, and improves digestion by relaxing intestinal muscles. Regular use strengthens circulation, calms your nervous system, and supports natural detoxification.

Q: How does dill help with muscle cramps and recovery?

A: Dill contains potassium, calcium, and vitamin K — nutrients that regulate muscle contraction and hydration. Dill pickle brine provides a natural electrolyte boost, which helps relieve cramping and speeds post-exercise recovery. The herb’s flavonoids also reduce oxidative stress, helping muscles repair and function more efficiently.

Q: Can dill support digestion and relieve bloating?

A: Yes. Dill’s natural oils have antispasmodic effects, meaning they relax the smooth muscles of your digestive tract. Drinking dill tea or adding fresh dill to meals helps relieve bloating, gas, and indigestion. It also stimulates bile production, which improves fat digestion and nutrient absorption.

Q: Does dill offer benefits for women’s health?

A: Research shows dill helps ease menstrual cramps and labor pain by relaxing uterine muscles. It achieves effects similar to NSAIDs — pain-relieving drugs — but without the side effects. Incorporating dill regularly in your diet, especially during your cycle, supports hormonal balance and comfort naturally.

Q: What are easy ways to use dill every day?

A: Use fresh dill as a seasoning for eggs, vegetables, and soups. Add it to smoothies, raw yogurt-based dressings, or herbal teas for daily antioxidant and digestive support. To make it easy to use year-round, freeze chopped dill in water using an ice cube tray for quick additions to meals. A small amount used consistently provides ongoing support for your muscles, gut, and heart.

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Posted by: | Posted on: November 4, 2025

Molecular Hydrogen on Boosting Fitness


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/11/02/molecular-hydrogen-boosting-fitness-performance.aspx

Analysis by Dr. Joseph Mercola     November 02, 2025

Story at-a-glance

  • Proper hydration is foundational for athletic performance, affecting endurance, muscle repair, and nutrient transport. Even slight dehydration reduces training effectiveness and slows recovery significantly
  • Molecular hydrogen acts as a selective antioxidant, neutralizing harmful free radicals while preserving beneficial ones that promote muscle growth, unlike conventional antioxidants that block exercise adaptations
  • Hydrogen water can be consumed 10 to 20 minutes before or after exercise for performance benefits. It’s safe, fast-acting, cumulative, and doesn’t interfere with natural training signals
  • Quality hydrogen devices require platinum-titanium electrodes and dual-chamber designs that produce 1.2-1.6 parts per million (ppm) dissolved hydrogen while venting byproducts like ozone and chlorine gas
  • Research on hydrogen water remains preliminary but promising, showing benefits for weekend exercisers and elite athletes, though more large-scale studies are needed for definitive protocols

Hydrogen-rich water is gaining attention in athletic circles, yet the science around it is still developing. To shed more light on this matter, Tyler LeBaron, Ph.D., appeared on the Regenerative Water Wisdom podcast by Carrie Drinkwine. Here, they discussed the science behind molecular hydrogen (H₂) and how it can benefit physical wellness, as well as how you can apply it to your own exercise regimen.1

I encourage you to watch the entire video, as it contains many nuggets of practical wisdom, especially if you’re looking to improve your athletic performance via molecular hydrogen. If you’re not an athlete, but just trying to improve your overall fitness, the knowledge explored here will still be helpful.

Hydration — A Key Player in Athletic Performance

Drinkwine and LeBaron set the stage by focusing on hydration as the hidden driver of energy, strength, and recovery. They explain that when you think about performance, you often think about training harder or eating better — but water is the foundation that holds it all together.

• You are made mostly of water and every cell in your body depends on it — Your blood, muscles, and even your joints rely on water to transport nutrients, remove waste, and keep things moving smoothly. That said, even if you’re slightly dehydrated, your endurance drops, your muscles don’t repair as well, and your overall effort in training can feel wasted. In other words, the harder you push while dehydrated, the less return you get for all that work.

• Always be conscious of your hydration status — Drinkwine points out that it is not enough to simply drink water once you’re already thirsty. You need to enter your workouts pre-hydrated and then sip consistently during activity. This way, your body has the minerals and electrolytes it needs before you ever start sweating. If you wait too long, you struggle to replace what is lost, and your performance suffers even more.

• Not all water is the same — Tap water, for example, often contains unwanted substances, while very high-pH waters might interfere with digestion by disrupting the stomach’s natural acidity. That means the quality of what you drink matters just as much as the amount. If you want your body to perform at its peak, Drinkwine and LeBaron’s discussion makes it clear that both hydration timing and water quality play a direct role in how well you train and recover.

• Hydration impacts performance — Drinkwine addresses regular lifters, runners, cyclists, and hot-yoga practitioners. For this group, she stresses outcomes that you feel right away when hydration supports physical endurance — smoother nutrient delivery, cooler body temperature, and faster bounce-back after hard sets or long miles. She frames endurance as “the longevity of your body’s ability to run, to cycle, to swim, to lift,” reminding you that hydration touches every part of that chain.

Drinkwine also noted that dehydration disrupts intracellular protein structures, damages cells, and blocks muscle repair, making a “hard-earned workout essentially worthless.”

Hydrogen Works with Your Body, Not Against It

LeBaron explained why H₂ is not only another antioxidant, but a unique support tool for athletes and anyone serious about exercise. He began by describing what happens during hard workouts — as your oxygen use rises toward its peak (VO₂) max, your body produces more free radicals.

While free radicals are usually associated with negative effects, some act as messengers that help your muscles grow stronger and your mitochondria multiply. LeBaron pointed out that the real challenge is maintaining balance, so you get the benefits without the excess strain on your system.

• High doses of common supplements can block the very signals your body needs from exercise — LeBaron noted that conventional antioxidants sometimes blunt improvements in strength, endurance, and even insulin sensitivity. Now, the problem is that these compounds are not selective. They wipe out both the harmful free radicals and the helpful ones, leaving you with fewer long-term gains.

Molecular hydrogen is different. Because of its tiny size and neutral charge, it diffuses into places other molecules cannot, like the inner compartments of your mitochondria. Once there, it neutralizes only the most destructive radicals, leaving the beneficial ones to continue their work.

• Why hydrogen stands apart from standard antioxidants — LeBaron described hydrogen as a “redox adaptogen,” meaning it adjusts to your body’s state rather than forcing one outcome. Unlike traditional antioxidants, hydrogen does not cancel the oxidative stress that drives growth. Instead, it reduces the overload that leads to fatigue, soreness, and cell injury. LeBaron emphasized that inflammation works the same way — short bursts are vital to trigger repair, but lingering inflammation slows recovery.

His research, published in the Canadian Journal of Physiology and Pharmacology,2 showed that hydrogen activates some of the same protective pathways as exercise itself. This is why he refers to it as an “exercise mimetic.” In other words, hydrogen mimics certain benefits of exercise, like upregulating the Nrf2 pathway, which boosts your body’s own antioxidant defenses.

• When and how to use hydrogen for training — While no single protocol has been proven as the best, LeBaron suggested that taking hydrogen-rich water before exercise — about 10 to 20 minutes in advance — works well for performance. Drinking it afterward is also beneficial, since it doubles as hydration.

• Hydrogen is described as both fast-acting and cumulative — In the short term, it helps you push through fatigue and recover faster. Over time, it strengthens your cellular defenses and energy systems, setting the stage for better performance overall. This makes it useful not just before competitions but also as a daily foundation in your training plan.

The safety profile is another major plus. Unlike many pre- and post-workout formulas loaded with stimulants and additives, hydrogen is simply dissolved gas in water. As LeBaron put it, “there doesn’t appear to be a wrong way to do it,” which makes it easy to integrate.

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Picking the Best Hydrogen Water

Drinkwine also discussed another important topic that deserves attention — which hydrogen-water devices truly deliver on their promises, and which ones waste your money. She warns you not to grab the first bottle you see online, because “not all hydrogen devices are created equal.” In essence, the build and the water chemistry, together, decide whether you truly get therapeutic hydrogen or just fancy bubbles.

Also, while they do not discuss the use of tablets in this interview, hydrogen tablets are a convenient and effective way to make hydrogen water. When using hydrogen tablets, make sure you consume the water immediately after preparation to ensure maximum benefit. Once all the bubbles have evaporated, the hydrogen is gone, so you want to drink it while it’s still fizzy.

• What separates high-quality devices from copycats — Drinkwine and LeBaron highlight the importance of electrodes coated in titanium and platinum to avoid metal leaching, plus a high-grade proton-exchange membrane to keep performance stable over time.

Another important point is the dual-chamber layout. It’s designed to let only pure hydrogen pass through the membrane while venting unwanted byproducts of electrolysis — specifically ozone and chlorine gas — so what you drink stays clean and consistent.

• The numbers produced matter — Drinkwine reports that bottles producing therapeutic levels of dissolved hydrogen are around 1.2 to 1.4 parts per million (ppm), sometimes reaching 1.6 ppm. She pairs those levels with water rules that keep the system in the sweet spot — pH below 7 and total dissolved solids (TDS) between 20 and 60.

Output is checked against oxidation-reduction potential (ORP) and an RH₂ reading to confirm the water’s reducing power.

• You get what you pay for — Drinkwine says that you need to do your homework. Look for coated platinum-titanium electrodes, a proven proton-exchange membrane, and a dual-chamber design that vents byproducts. Ultimately, water quality still matters — avoid overly alkaline setups and watch for contaminants found in typical tap water, since both work against the performance you’re chasing.

Simple Steps to Incorporate Hydrogen Water During Training

LeBaron and Drinkwine lay out what you can do to make hydrogen-rich water part of your training. Below, they share their experience in timing, consistency, and hydration basics to create stronger workouts and quicker recovery:

• When to drink hydrogen water — Again, LeBaron explains that taking hydrogen water before training — about 10 to 20 minutes ahead — helps you feel a performance boost. He adds that drinking it right after also makes sense, because you’re replenishing hydration while your body is in recovery mode. Carrie points out that both ways work, and for many people, both pre- and post-workout use feels best.

• Hydrogen water isn’t like caffeine — With caffeine, you need to time it properly and deal with side effects later, like jitters or trouble sleeping.

Conversely, hydrogen works differently — it doesn’t overstimulate your system. Instead, it influences gene expression and recovery pathways that build up over time. This is why LeBaron suggests making it a daily habit, not just an occasional pre-workout trick.

• How to keep your body’s natural signals intact — Both LeBaron and Drinkwine emphasize that it’s not wise to drown your system in heavy antioxidant supplements, because those blunt the good stress signals from exercise that help you grow stronger.

In this case, hydrogen water stands out because it doesn’t interfere with those signals — it supports your body’s ability to adapt. As Drinkwine summarizes, it feels “so pure” compared to pre- or post-workout powders full of fillers and chemicals.

• Hydrogen water works, but it’s not magic — Both Drinkwine and LeBaron emphasize the basics — hydrogen water is an enhancer, not a replacement. Sleep, nutrition, and plain hydration still come first. Drinkwine shares her own experience of training longer and harder without burning out, but she also notes that it’s part of a larger routine built on lifting, running, yoga, and healthy recovery.

The Field Is Still Growing

LeBaron acknowledges that research into hydrogen-rich water is still in its early stages. He stresses that while findings so far are promising, the number of large-scale human trials are still small compared to more established areas of sports science.

• The specifics are not final yet — In his own words, “hydrogen is still in its infancy,” pointing out that we don’t yet have a single, universally accepted protocol for dosing or timing. Instead, most recommendations are based on what’s known about how hydrogen interacts with the body, along with smaller studies that have reported positive effects.

• Much of the evidence today is a mix of structured studies and real-life stories — LeBaron references a meta-analysis published in Frontiers in Physiology, which concludes hydrogen has anti-fatigue effects and reduces harmful oxidative stress.3

At the same time, Drinkwine emphasizes that many people’s personal reports — lifting more reps and handling hot yoga with steady energy — show an important role in showing hydrogen’s promise.

• Another caveat is about who benefits the most — According to LeBaron, hydrogen-rich water seems especially helpful for two types of athletes — the “weekend warriors” who train hard only occasionally and often overload their bodies, and elite athletes who push themselves daily to extremes.

• More clarity is needed around the exact mechanisms — LeBaron notes that while hydrogen is shown to influence pathways like Nrf2, scientists are still working to map out the full picture. Carrie echoes this by admitting that while her results feel dramatic, she doesn’t yet feel comfortable making hard clinical claims until more long-term trials are published.

The key takeaway is clear — hydrogen water is safe, promising, and supported by both studies and anecdotes. But again, it’s still a growing field. So, make sure you stay updated as more research is completed.

Frequently Asked Questions (FAQs) on Molecular Hydrogen for Exercise

Q: Why is hydration so important for athletic performance?

A: Hydration is the foundation of energy, strength, and recovery. Your muscles, blood, and joints all depend on water to transport nutrients, remove waste, and regulate body temperature. Even slight dehydration lowers endurance, slows muscle repair, and makes workouts feel harder. Entering workouts already hydrated and sipping consistently during activity helps you perform better and recover faster.

Q: How does hydrogen-rich water differ from regular antioxidants?

A: Hydrogen-rich water works with your body’s natural processes instead of wiping them out. Regular antioxidants can block both harmful and beneficial free radicals, which reduces the positive effects of exercise. Hydrogen is different — it only neutralizes the most damaging radicals while leaving the helpful ones in place. This balance means you get less fatigue and soreness while keeping the growth signals that make you stronger.

Q: When should I drink hydrogen-rich water for the best results?

A: LeBaron recommends drinking hydrogen-rich water about 10 to 20 minutes before exercise to support performance. It’s also useful immediately after training because it doubles as hydration and recovery support. Over time, daily use builds up benefits at the cellular level, helping your energy systems and recovery pathways become stronger.

Q: What should I look for in a hydrogen water device?

A: Not all hydrogen devices deliver true therapeutic levels. High-quality bottles use platinum-coated titanium electrodes and a proton-exchange membrane to ensure stability and safety. A dual-chamber design vents unwanted gases like ozone and chlorine while letting only pure hydrogen into the water.

Look for devices that produce 1.2 to 1.6 parts per million of dissolved hydrogen with a pH under 7 and total dissolved solids between 20 and 60. One of the easiest and most convenient ways to make hydrogen water is to use hydrogen tablets — just make sure to drink it while it’s still fizzy.

Q: Is hydrogen-rich water proven, or is research still early?

A: The science is promising but still developing. Reviews show that hydrogen water reduces fatigue and oxidative stress without blocking beneficial exercise signals. However, researchers stress that more large-scale, long-term trials are needed. Anecdotal reports add encouraging evidence, but it’s important to see hydrogen water as an enhancer, not a replacement for fundamentals like sleep, nutrition, and regular hydration.

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Posted by: | Posted on: April 1, 2025

Mitochondrial Dysfunction in Neurodegenerative Disorders


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/03/31/mitochondrial-dysfunction-neurodegeneration.aspx

Analysis by Dr. Joseph Mercola     March 31, 2025

mitochondrial dysfunction neurodegeneration

STORY AT-A-GLANCE

  • Mitochondrial dysfunction is a key driver of neurodegeneration, with research showing that a single resting cortical neuron requires 4.7 billion ATP molecules every second for energy
  • When mitochondria lose their efficient shape, electrons escape and form reactive oxygen species (ROS), triggering cellular damage and stress that particularly affects brain cells
  • Research shows 42% of adults over 55 develop dementia by age 95, with projected new cases expected to double from 514,000 in 2020 to 1 million by 2060
  • Mitochondria act as cellular calcium buffers — when this function fails, calcium floods cells and triggers the mitochondrial permeability transition pore, leading to widespread neuron death
  • Key mitochondrial health strategies include eliminating seed oils, optimizing carbohydrate intake, reducing environmental toxin exposure, getting proper sun exposure and boosting NAD⁺ levels through supplements

You might be startled to learn that 42% of adults over 55 develop dementia by age 95.1 Dementia is characterized by memory loss, difficulties with language and reasoning, and an overall decline in the ability to perform everyday tasks. Left unmanaged, it spirals into more severe neurodegenerative disorders that undermine independence and quality of life.

A review published in Neurotherapeutics further highlights that a single resting cortical neuron consumes 4.7 billion adenosine triphosphate (ATP) molecules every second, underscoring how energy demands in your brain are immense and ongoing.2

I see this as direct evidence of why supporting cellular powerhouses — your mitochondria — is so central to preserving cognitive health. Chronic disruptions in those energy processes impose relentless stress on nerve cells, paving the way for memory problems and other neurological setbacks.

Mitochondrial Dysfunction Is at the Root of Neurodegeneration

The Neurotherapeutics review3 examined how different forms of disrupted energy processes in brain cells set the stage for progressive neurological disease. The researchers looked at various research findings that link faulty mitochondrial function to disorders affecting cognition, motor control and other higher-level tasks.

Their central goal was to pinpoint how malfunctioning mitochondria trigger the chain reactions seen in conditions such as Alzheimer’s disease, Parkinson’s disease and multiple other neurological syndromes.

• Evidence reveal how mitochondrial dysfunction drives brain changes — Investigators in this review did not limit their analysis to a specific group of patients. Instead, they consolidated evidence from a broad range of laboratory experiments and clinical observations targeting aging populations, individuals with rare mitochondrial disorders and those carrying known genetic mutations that alter mitochondrial function.

By weaving these areas together, the authors hoped to create a clearer picture of how compromised energy production leads to characteristic brain changes.

• Even small changes lead to significant damage — One of the paper’s most striking observations is how tiny structural shifts inside the mitochondria snowball into large-scale damage.4 When these organelles lose their efficient shape, electrons slip out of the normal energy pathway and team up with oxygen to form corrosive molecules called reactive oxygen species (ROS).

That surge in ROS sets off a cascade of biochemical stressors throughout brain cells, including direct attacks on important proteins and fats.

• The mitochondrion’s structure has a substantial role in neurofunction — As the authors state, “Excessive ROS production damages a variety of cellular components including proteins, lipids and DNA.”5 In short, the mitochondrion’s shape and integrity hold more power over neurofunction than many imagine.

Apart from the physical shape, researchers also honed in on the role of calcium balance. Healthy mitochondria function as a buffer by absorbing and releasing calcium ions to keep cells in balance.6

• The mitochondrial permeability transition pore leads to cell death — Once there’s a glitch, calcium floods the cell, and an emergency process called the mitochondrial permeability transition pore springs open.

The paper emphasizes that an uncontrolled opening of this pore triggers a wave of cell death, especially in your brain’s vulnerable neurons, where energy demands are already sky-high. It’s like watching a dam collapse because the main floodgate jammed.

Another intriguing angle involves how failing mitochondria disturb normal protein cleanup processes in the cell.7 The authors detail a scenario in which damaged mitochondria release proinflammatory signals, slowing down or outright blocking autophagy, the system cells use to clear out junk.

This slowdown contributes to the buildup of toxic plaques and misfolded proteins that characterize several neurodegenerative conditions. In practical terms, it means that your body’s usual housekeeping can’t keep up with the mess, and your brain is the unfortunate casualty.

Mitochondrial Dysfunction Tied to Parkinson’s, Alzheimer’s and Other Disorders

Throughout the review, there’s a clear focus on how each neurodegenerative disease taps into similar mitochondrial weaknesses.8 For instance, while Parkinson’s disease involves a breakdown in dopamine-producing neurons, and Alzheimer’s centers on beta-amyloid plaques, both conditions involve disruption of electron transport inside the mitochondria.

• One targeted intervention can influence many conditions — By comparing these processes side by side, the authors illustrate how one targeted intervention has benefits across multiple disorders. It’s a refreshing perspective that encourages looking beyond siloed research for cures or therapies. The researchers also address how the paper’s findings reflect on the broader population and our understanding of age-related memory and motor decline.9

• The connection between normal aging and mitochondrial collapse — They connect the dots between normal aging, which often features mild mitochondrial dysfunction, and more severe mitochondrial collapse seen in advanced disease states.

That means many people could be slipping down this slope long before typical symptoms even appear. According to the paper, identifying biomarkers of mitochondrial damage helps clinicians detect disease pathways early enough for effective interventions.

• ROS production modifies cellular signals — The authors also describe an intricate sequence of oxidative reactions that damage DNA, disrupt telomeres — the protective caps at the ends of chromosomes — and even alter the way genes are expressed.10

The review suggests that once ROS production speeds up, it doesn’t just drain energy — it also modifies cellular signals that keep neurons alive and functional. These modifications eventually tip cells into an energy crisis they cannot recover from, leading to unstoppable cell loss.

• Antioxidants help stabilize electron transport — Additionally, there’s discussion of how certain antioxidant strategies might stabilize electron transport by shielding the delicate proteins and lipids inside mitochondria.11

Some early-phase clinical trials, the paper notes, show promise in using compounds that block the worst of the oxidative assaults. While these lines of research are still evolving, they shine a bright light on the possibility of halting mitochondrial problems before serious neurological damage becomes entrenched.

Overall, this review underscores that protecting your cell’s power plants is a direct route to preserving brain function.12 By mapping the many crossroads where mitochondrial decline intersects with cognitive decline, researchers open doors to therapies that restore healthy energy production and help you maintain sharper memory, better coordination and greater resilience in the face of escalating demands on your brain.

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The Growing Alzheimer’s Risk in Aging Populations

Understanding mitochondrial dysfunction’s role in neurodegeneration becomes urgent in the face of rising dementia cases. A study published in Nature Medicine13 tackled a massive data set on dementia, focusing on which groups are diagnosed most often, how early in life it occurs and how these trends shift over time.

Rather than exploring microscopic changes in the brain, this work looked closely at how social, genetic and age-related elements determine whether someone develops cognitive decline.

• Identifying the role of APOE ε4 in dementia development — Investigators pulled from a community-based study of thousands of participants, each free of dementia at the start, but varying in age, background and genetic traits.14 Their top priority was to measure how a person’s chances of developing dementia changed when factors such as sex, race and a specific genetic marker known as APOE ε4 came into play.

• Differences were seen between genders — By layering in long-term follow-up data and population statistics, they aimed to predict how many new dementia diagnoses would appear each year over the next several decades. A closer look revealed some dramatic differences between men and women.15

The paper found that women’s overall risk for dementia was higher than men’s when viewed across a lifetime, even though men often faced a greater likelihood of dying from other causes before cognitive problems fully manifested.

• Hormonal factors amplify the toll — In simpler language, men did not always reach the ages at which dementia most commonly appears. This gap sparked questions about how unique hormonal factors and longer lifespans amplify the toll on older women.

The same research found that Black adults were diagnosed with dementia at higher rates than White adults.16 This trend kicked in earlier, hinting that certain structural or social conditions accelerate the onset of memory loss.

• Certain factors affect dementia development — The paper noted that higher burdens of vascular complications, challenges with health care access and long-standing inequities could be part of the reason more Black adults developed dementia at younger ages. Investigators highlighted yet another twist: the APOE ε4 gene variant.17

This genetic factor often signals a heightened risk of Alzheimer’s disease, which falls under the broader dementia umbrella. Individuals carrying one copy showed a higher likelihood of facing cognitive problems, and those carrying two copies saw their odds jump even further.

• Dementia cases can rise to 1 million by 2060 — Looking ahead, the paper revealed a stark projection: around 514,000 new dementia cases occurred in 2020, but that total is expected to hit roughly 1 million by 2060.18 This doubling in newly diagnosed individuals points to significant population aging, where large segments of people are moving into the higher-risk age brackets at once.

Overall, the Nature Medicine paper19 suggests that the growing number of new dementia cases will not slow unless older adults gain more consistent access to early detection, better lifestyle options and interventions that protect their cognitive abilities — including optimizing your mitochondrial function.

How to Support Mitochondrial Health

You deserve straightforward ways to tackle an actual cause of neurodegeneration: a drop in cellular energy that wears down your nerve cells. I believe that if you support your mitochondria properly, you strengthen your brain and spare yourself from many issues that come with mitochondrial dysfunction. Below are five steps that focus on restoring mitochondrial health to boost your cellular power:

1. Eliminate processed foods and seed oils — I recommend shifting your diet away from seed oils like corn, soybean, safflower or canola. These oils contain linoleic acid (LA), a mitochondrial poison that compromises your cellular energy production. Aim to center your meals around wholesome foods such as fresh vegetables, grass fed butter or tallow, and clean collagen-rich proteins.

If you’re eating out, confirm what kind of oil they use in the kitchen — and opt out if it’s seed oil. This step helps protect your mitochondria from damage that accumulates over time, ultimately preserving your brain’s vitality.

2. Optimize your carbohydrate intake — Certain carbs are essential for steady energy output, especially keeping your neurons fueled. If you have a compromised gut, it’s important to start with easier-to-digest options, like white rice or slowly sipping dextrose water.

Over time, work in whole fruits and other nutrient-dense carbs. If you’re active, your needs are higher, so tailoring your intake ensures you’re not draining your mitochondria by consuming a low-carb diet.

3. Reduce exposure to environmental toxins — Your cells get bombarded by synthetic chemicals daily. Exposure to endocrine-disrupting chemicals (EDCs) in plastic, estrogen and pervasive electromagnetic fields (EMFs) impairs your cells’ ability to generate energy efficiently. As these pollutants build up, the mitochondria lose efficiency.

That’s why I recommend being proactive about reducing your exposure to environmental toxins. Consider household products made from natural materials and glass storage for leftovers. Sleeping in an EMF-free environment is also important, as it gives your cells a breather while your body recharges overnight. All of this lowers the stress your body must handle.

4. Get proper sun exposure — Daily sun exposure is important as it promotes cellular energy production by stimulating mitochondrial melatonin, offering powerful antioxidant protection. Avoid direct sunlight during peak hours (from 10 a.m. to 4 p.m. in most U.S. regions) until you’ve eliminated seed oils from your diet for at least six months, because accumulated LA in your tissues make you sunburn more easily.

5. Boost NAD+ Levels — Take niacinamide (50 milligrams three times daily) to increase NAD+ production, which helps your mitochondria generate more energy. NAD+ enables proper cell death signaling and supports your immune system’s ability to identify and remove damaged cells.

Frequently Asked Questions (FAQs) About Mitochondrial Dysfunction

Q: Why are mitochondria so important for brain health?

A: Mitochondria are the brain’s energy powerhouses, with a single resting cortical neuron using 4.7 billion ATP molecules every second. Mitochondrial dysfunction leads to energy deficits, oxidative stress, and neuron damage — all contributing to neurodegenerative diseases.

Q: How does mitochondrial dysfunction contribute to neurodegenerative disorders like Alzheimer’s and Parkinson’s?

A: Damaged mitochondria release reactive oxygen species (ROS) and disrupt calcium balance, triggering cell death and blocking cellular cleanup systems. This process causes toxic buildup and accelerates conditions such as Alzheimer’s and Parkinson’s.

Q: How widespread is dementia, and what are future projections?

A: Currently, 42% of adults over 55 develop dementia by age 95. New dementia cases are projected to double from 514,000 in 2020 to around 1 million by 2060 due to an aging population and genetic risk factors like the APOE ε4 gene variant.

Q: What lifestyle factors help protect mitochondrial function and reduce neurodegeneration risk?

A: Key strategies include eliminating seed oils, optimizing healthy carbohydrates, minimizing exposure to environmental toxins, getting proper sun exposure, and boosting NAD+ levels through niacinamide supplementation.

Q: What early signs and interventions are emphasized in preventing cognitive decline?

A: Detecting mitochondrial damage early through biomarkers, along with antioxidant therapies and targeted lifestyle changes, can help slow or prevent the onset of neurodegenerative diseases and age-related memory decline.

 

– Sources and References

Posted in Alzheimer's, Antioxidant, Brain, Linoleic Acid, Mitochondria | No Comments »

Posted by: | Posted on: March 11, 2025

Lemon: 12-Evidence Based Health Benefits

© GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC.
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Reproduced from original article:
https://greenmedinfo.com/blog/lemon-rx-12-evidence-based-reasons-why-it-powerful-medicine
Posted on:  Wednesday, July 31st 2019 at 4:30 pm

Written By:  Sayer Ji, Founder
This article is copyrighted by GreenMedInfo LLC, 2019
Lemon Rx: 12 Evidence-Based Reasons Why It is A Powerful Medicine

You know lemon, right? It is a tart, exciting, delicious and indispensable ingredient in recipes and beverages. But did you know that scientists have identified it is as a powerful medicine as well?

The most powerful healing substances on this planet are masquerading as foods, and this is all the more true for fruits.  I’ve already written about The Amazing Healing Properties of 13 Common Fruits , including lemons, but it deserves its own mini-article for a number of reasons.

Here are 12 reasons why it deserves respect as a cutting-edge medicine, and not just something found in refreshing beverages or as an indispensable ingredient in a number of culinary recipes.

Lemon’s Evidence-Based Healing Properties Revealed:

  1. It Can Lower Blood Pressure: Simply smelling this fruit has been found in lower blood pressure.[1]
  2. It Can Lessen Constipation: In combination with rosemary and peppermint essential oil, the smell of lemon has been found to relieve constipation in the elderly.[2]
  3. It Can Remedy Bad Breath: In combination with tea tree and peppermint essential oil, it can reduce malodour and sulphur compounds in the breath of intensive care patients.[3]
  4. It Can Reduce Esophageal Cancer Risk: Lemon, like all citrus fruits, contains physiological significant levels of flavones; Flavone intake has been found to be inversely associated with esophageal cancer risk. [4]
  5. Oral Yeast Infection: Lemon juice has therapeutic value in the treatment of oral thrush (oral candida infection) in HIV/AIDS patients. [5]
  6. It Can Dissolve Kidney Stones:  Lemonade therapy appears to be a reasonable alternative for patients with hypocitraturic nephrolithiasis (a type of kidney stone).[6] [7]
  7. It Can Reduce Inflammation:  Lemon mucilage has significant in vivo and in vitro anti-inflammatory effects.[8]
  8. It Can Protect Your Heart: Lemon juice antioxidant and cardioprotective properties. [9]
  9. It Can Protect Against Cholera: Lemon juice is a biocide against Vibrio cholerae, the pathogen that can cause cholera.[10]
  10.  It Is A Powerful Antioxidant and Prevents LDL Oxidation: Excessive oxidative stress is a contributing factor to accelerating aging, inflammation and a wide range of acute and chronic health conditions. One of the primary reasons why LDL cholesterol can cause heart disease is that it oxidizes LDL cholesterol, resulting in artherogenicity (the ability to damage the inner lining of the arteries). Lemon is a powerful antioxidant and is capable of preventing LDL oxidation.[11]
  11. It Can Help Lift Your Mood and Reduce Anxiety: Lemon oil possesses anxiety relieving (anxiolytic), antidepressant-like via modulation of neurotransmitters.[12]
  12. It Can Help You Maintain An Ideal Weight: Lemon peel polyphenols suppress diet-induced obesity, hyperlipidemia, hyperglycemia and insulin resistance.[13

In addition, lemon is also one of the most concentrated sources of food vitamin C on the planet. Unlike ascorbic acid – which is the synthetic form of vitamin C, commonly derived from GMO corn – lemon contains all the essential cofactors needed to provide the body the means to utilize it, and maximize its effectiveness in disease prevention and treatment (Pssssst. Please don’t tell the FDA, since its not approved to ‘prevent, treat, or cure any disease,’ and they wouldn’t’ look kindly on this statement).

For more information on the healing properties of lemon, view our lemon database and share this information far and wide. Also, learn more about the amazing healing properties of vitamin C by reading Research Proving Vitamin C’s Therapeutic Value in 200+ Conditions.

REFERENCES t[1] Jung Hee Cha, Sun Hee Lee, Yang Sook Yoo. [Effects of aromatherapy on changes in the autonomic nervous system, aortic pulse wave velocity and aortic augmentation index in patients with essential hypertension]. J Korean Acad Nurs. 2010 Oct;40(5):705-13. PMID: 21157172 [2] Myung-Ae Kim, Jung-Kyu Sakong, Eun-Jin Kim, Eun-Ha Kim, Eun-Ha Kim. [Effect of aromatherapy massage for the relief of constipation in the elderly]. Taehan Kanho Hakhoe Chi. 2005 Feb;35(1):56-64. PMID: 15778557 [3] Myung-Haeng Hur, Joohyang Park, Wendy Maddock-Jennings, Dong Oak Kim, Myeong Soo Lee. Reduction of mouth malodour and volatile sulphur compounds in intensive care patients using an essential oil mouthwash. J Nutr. 2002 Apr;132(4):703-7. PMID: 17380550 [4] Marta Rossi, Werner Garavello, Renato Talamini, Carlo La Vecchia, Silvia Franceschi, Pagona Lagiou, Paola Zambon, Luigino Dal Maso, Cristina Bosetti, Eva Negri. Flavonoids and risk of squamous cell esophageal cancer. Arch Intern Med. 2000 Apr 10;160(7):1009-13. PMID: 17192901 [5] S C Wright, J E Maree, M Sibanyoni. Treatment of oral thrush in HIV/AIDS patients with lemon juice and lemon grass (Cymbopogon citratus) and gentian violet. Phytomedicine. 2009 Mar;16(2-3):118-24. Epub 2008 Dec 23. PMID: 19109001 [6] David E Kang, Roger L Sur, George E Haleblian, Nicholas J Fitzsimons, Kristy M Borawski, Glenn M Preminger. Long-term lemonade based dietary manipulation in patients with hypocitraturic nephrolithiasis. J Urol. 2007 Apr;177(4):1358-62; discussion 1362; quiz 1591. PMID: 17382731 [7] Mohammed Touhami, Amine Laroubi, Khadija Elhabazi, Farouk Loubna, Ibtissam Zrara, Younes Eljahiri, Abdelkhalek Oussama, Félix Grases, Abderrahman Chait. Lemon juice has protective activity in a rat urolithiasis model. BMC Urol. 2007 Oct 5;7:18. PMID: 17919315 [8] Enza Maria Galati, Antonia Cavallaro, Tommaso Ainis, Maria Marcella Tripodo, Irene Bonaccorsi, Giuseppe Contartese, Maria Fernanda Taviano, Vincenzo Fimiani. Anti-inflammatory effect of lemon mucilage: in vivo and in vitro studies. Immunopharmacol Immunotoxicol. 2005;27(4):661-70. PMID: 16435583 [9] Yoshiaki Miyake, Mika Mochizuki, Miki Okada, Masanori Hiramitsu, Yasujiro Morimitsu, Toshihiko Osawa. Isolation of antioxidative phenolic glucosides from lemon juice and their suppressive effect on the expression of blood adhesion molecules. Biosci Biotechnol Biochem. 2007 Aug;71(8):1911-9. Epub 2007 Aug 7. PMID: 17690486 [10] M C de Castillo, C G de Allori, R C de Gutierrez, O A de Saab, N P de Fernandez, C S de Ruiz, A P Holgado, O M de Nader. Bactericidal activity of lemon juice and lemon derivatives against Vibrio cholerae. Biol Pharm Bull. 2000 Oct;23(10):1235-8. PMID: 11041258 [11] J Grassmann, D Schneider, D Weiser, E F Elstner. Antioxidative effects of lemon oil and its components on copper induced oxidation of low density lipoprotein. Arzneimittelforschung. 2001 Oct;51(10):799-805. PMID: 11715632 [12] Migiwa Komiya, Takashi Takeuchi, Etsumori Harada. Lemon oil vapor causes an anti-stress effect via modulating the 5-HT and DA activities in mice. Behav Brain Res. 2006 Sep 25;172(2):240-9. Epub 2006 Jun 15. PMID: 16780969 [13] Yoshiko Fukuchi, Masanori Hiramitsu, Miki Okada, Sanae Hayashi, Yuka Nabeno, Toshihiko Osawa, Michitaka Naito. Lemon Polyphenols Suppress Diet-induced Obesity by Up-Regulation of mRNA Levels of the Enzymes Involved in beta-Oxidation in Mouse White Adipose Tissue. J Clin Biochem Nutr. 2008 Nov;43(3):201-9. Epub 2008 Oct 31. PMID: 19015756

Article updated: 2019-07-30

Sayer Ji

Sayer Ji is founder of Greenmedinfo.com, author of international best-seller REGENERATE: Unlocking Your Body’s Radical Resilience through the New Biology, co-founder of Stand for Health Freedom (501c4), and UNITE.live, a global, multi-media platform for conscious creators and their communities.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.

Posted in Antioxidant, Food, Vitamins | No Comments »

Posted by: | Posted on: March 2, 2025

Research links excessive oxalates to breast cancer

Reproduced from original article:
https://www.naturalhealth365.com/research-links-excessive-oxalates-to-breast-cancer.html

by: | February 19, 2025

oxalates(NaturalHealth365)  Information about little-known compounds called oxalates can be confusing and conflicting.  They are often equated with the “bad” substances in foods, but, in reality, oxalates are neither good nor bad.  They can become problematic, however, when too many of them accumulate in the body.

When there are too many oxalates – they can overwhelm the kidneys and lead to kidney stones and immune deficiency.  Furthermore, research indicates that high levels of oxalate in the mammary area have been linked to breast cancer tumor growth as well.

The body itself forms most oxalates

Oxalates (COOH), or oxalic acid, are strongly acidic substances that help plants and animals metabolize.  The body’s functions form about 60% to 80% of oxalates.  The other 20 to 40% of oxalates come from food.

Most fruits and vegetables contain a small amount of oxalic acid, and they are found in the leaves of plants as opposed to the roots, stalks, and stems.  The following foods contain a high amount of oxalates overall:

  • Rhubarb
  • Chocolate
  • Spinach
  • Beet greens
  • Swiss chard
  • Some nuts, especially almonds, cashews, and peanuts
  • Some berries, especially gooseberries
  • Lemon and lime peel
  • Some grains and pasta (except brown rice)
  • Some legumes, especially navy beans, black beans, and soybeans
  • Okra
  • Parsley

How are oxalates linked to breast cancer?

Oxalates are oxidizing substances.  As such, they are extremely volatile and can damage tissue in large amounts.  Oxalate crystals cause the formation of kidney stones, which can block the flow of urine and lead to kidney infection and bladder cancer.

These crystals are also razor sharp and can cause direct damage and long-lasting inflammation to whatever internal tissues they come into contact with.  Oxalate-iron crystals can lead to iron depletion.  When calcium-oxalate crystals form, they can lodge in internal organs and bone.  As they grow, they crowd out bone marrow, leading to immune deficiency and anemia.

Excess oxalates also can chelate heavy metals.  However, oxalates trap metals like mercury and lead in tissues, unlike other chelators.  Excess oxalate has been linked to fibromyalgia, vulvodynia (vulvar pain), digestive disorders, and autism.

The most startling new connection between excess oxalates and disease has to do with breast cancer, however.  A study conducted by the National University of Cordova in Argentina compared the oxalate levels of breast cancer tumor tissue and regular breast tissue.  They found that “all tested breast tumor tissues contain a higher concentration of oxalates than their counterpart non-pathological breast tissue.”

The researchers also discovered that oxalic acid caused tumor proliferation and stimulated the expression of pro-tumor genes.  Surprisingly, proliferation did not happen when oxalate was injected into the backs of laboratory mice.  This indicates that high oxalate levels do not induce cancer tumor growth in all types of tissue.

Three ways to reduce your oxalate levels

Obtain calcium from natural foods, not calcium supplements.

Calcium has an interesting relationship with oxalates.  Approximately 5-15% of the world population will develop some form of kidney stone.  Of those, 80% will be calcium-oxalate stones.  When calcium is combined with foods that are high in oxalates within the intestines, the two together form an oxalate-calcium crystal that the body cannot absorb.

When this happens, a “stone” is formed that will make its way to the kidneys to eventually be eliminated in the urine.  The presence of oxalate-calcium crystals, which can block urine flow and cause kidney infection, can also lead to a higher risk of renal, pelvis, and bladder cancers.  These same kinds of crystals can also form in the lungs, nerves, brain, bones, blood vessels, and joints.

Does this mean you should limit calcium intake if you are prone to kidney stones?  Not necessarily.  Research conducted on vegetarians found that they did not have higher-than-normal rates of calcium deficiency or osteoporosis caused by oxalate interference.

In fact, according to a study published in the European Journal of Epidemiology, vegetarians had a lower rate of kidney stones than meat eaters did.  Those who consumed calcium supplements regularly, however, have shown time and again to have higher rates of kidney stones.  Calcium supplementation has also been linked to both prostate and breast cancer.  Stick to natural and preferably vegetable and fruit-based calcium sources to avoid kidney stones and cancer.

Be aware of your protein intake.

Be cautious about protein, especially if it is derived from meat and dairy.  Oxalates are produced from amino acids in the liver.

Amino acids are the building blocks on which proteins are made so some researchers make the connection between total protein amounts and total oxalates formed.  For meat-eating women, the general recommendation is around 5 ounces a day.  This is equivalent to a small hamburger patty or four eggs.  The USDA states that, on average, Americans eat 30% more meat protein than the recommended allowance.

Maintain good intestinal flora.

According to research, some individuals have a physiology prone to higher levels of oxalate uptake in the digestive tract (thus, a higher risk of kidney stones).  Although there is evidence to suggest that hereditary disposition plays a role for some people, there is also a strong link between kidney stone formation and disorders of the digestive system, such as inflammatory bowel disease, leaky gut, and Crohn’s.

Could oxalate hyper-absorption have more to do with extreme gut flora imbalance than genetics?  The jury is still out on that one.  What is known, however, is that it is the job of specific flora, in particular, certain species of Oxalobacter formigenes, Lactobacillus, and Bifidobacteria, to process oxalic acid and prepare it for absorption.  Currently, there are several studies underway which focus on the role of oral probiotics in this process.

Let food work for you to keep oxalate levels in balance

Remember that problems only emerge when there is an excess of oxalates in the system.  The standard American diet contributes to oxalate overload, but you can also keep it in check by being proactive with prevention.  Eating antioxidant-rich food, consuming citrate-rich lemon and lime juice (which experts say can help prevent calcium-oxalate kidney stones), staying hydrated, and watching your salt intake are other ways to keep kidney stones in check.

Also, don’t let the fear of kidney stones prevent you from getting adequate amounts of vitamin C and D.  One of the ways that oxalates are formed is through conversion from vitamin C.  However, studies thus far have been inclusive as to whether high vitamin C intake actually leads to increased oxalate production.

In regards to vitamin D, deficiency of this vital substance has reached pandemic proportions in the developed world, including among those who have experienced kidney stones.  Be sure to get your levels checked the next time you get blood work done.  Maintaining a healthy balance of all substances in the body, including oxalates, is the only way to achieve and experience true health naturally.

Sources for this article include:

NIH.gov
NIH.gov
Oxfordjournals.org
MDPI.com
NIH.gov
NIH.gov
NIH.gov
Sciencedaily.com
Scientificamerican.com
Nutrition.org

 

Posted in Antioxidant, Cancer, Food, Kidney, Oxalates, Vitamins | No Comments »

Posted by: | Posted on: January 27, 2025

Rejuvenate your cellular health and turn back the clock on aging with a delicious fruit

Reproduced from original article:
https://www.naturalhealth365.com/turn-back-the-clock-on-aging-with-this-delicious-fruit.html

by: | January 25, 2025

pomegranate-improves-cellular-function(NaturalHealth365)  With their vibrant scarlet color and sweet-but-tart flavor, pomegranates have become an increasingly popular (and delicious) addition to salads, dressings, beverages, and desserts.  They are also a proven superfood, credited by researchers with the potential to prevent and help resolve many health problems.

A Swiss study shows that urolithin A, a molecule produced when pomegranate is digested, could hold the key to rejuvenating cell mitochondria and even prolonging the quality of your life.  In addition, a new review published in Molecules explores how pomegranate’s bioactive compounds, including urolithin A, can combat “inflammaging” – a chronic, low-grade inflammation associated with aging and many age-related diseases.  These findings highlight pomegranate’s potential to slow the aging process and improve overall health.

Let’s take a closer look at urolithin A and its amazing restorative potential.

Pomegranate triggers urolithin A to rejuvenate the powerhouse of our cells

Mitochondria are tiny structures inside cells with the all-important task of turning fuel into energy.  Over time, however, they can degrade and deteriorate.

In young, healthy cells, these aging and damaged mitochondria are swiftly broken down and eliminated.  This beneficial process, known as mitophagy, helps to ensure optimal cellular function.

Mitophagy becomes less efficient with age, causing malfunctioning mitochondria to accumulate in cells.  These mitochondrial debris deposits weaken muscle tissues and impair cellular health.  Researchers believe that these deposits can trigger degenerative disorders such as Parkinson’s disease, as well as decreased mobility and frailty in elderly people.

This is where pomegranates come in…

The body produces a molecule called urolithin A upon digesting two polyphenols – punicalagins and ellagitannins – that exist naturally in pomegranates.  In many studies, this newly discovered molecule was shown to induce mitophagy and prevent the accumulation of dysfunctional mitochondria.

New study reveals stunning results, as we age

In a study published in Nature Medicine, researchers found that urolithin A maintained mitochondrial respiratory capacity and extended the lifespan of C. elegans – a short-lived worm commonly used in longevity studies – by a stunning 45 percent.

The research suggests that consuming pomegranate extracts can boost levels of urolithin A, enhancing mitochondrial function and improving muscle quality.

Researchers noted that this finding holds particular significance for elderly people.  By helping to enhance muscle function, urolithin A may help ward off the loss of mobility and general decline that can accompany weakened muscle tissue.

The team called urolithin A a “promising approach to improving mitochondrial and muscle function in the aging population ” and called for further research.

Pomegranate has a proven ability to combat heart disease and cancer

The above studies are not the only ones to reveal important health benefits from pomegranates – these tasty members of the berry family have impressed researchers with their ability to combat serious degenerative diseases.

In a review published in Advanced Biomedical Research, the authors noted that pomegranate could help prevent or treat a veritable laundry list of dangerous conditions that trigger potentially life-threatening diseases – including high blood pressure, high cholesterol, oxidative stress, high blood sugar, atherosclerosis, and inflammation.

Interestingly, in some cases, pomegranate extracts have been found to work in much the same way as pharmaceutical medications.  For instance, pomegranate extracts help suppress pro-inflammatory COX-2 and tumor necrosis factor-alpha, much like anti-inflammatory drugs do.  When it comes to regulating blood pressure, pomegranate extracts seem to function like ACE inhibitors, a group of pharmaceutical hypotensive medications.

Studies have also shown that pomegranates reduce the incidence of tumors, reduce the number and size of cancerous stem cells, and induce apoptosis – or cancer cell death.  Pomegranate extracts are currently used to help people with a variety of cancers, including those of the prostate, breast, colon, lung, and skin.

Finally, pomegranate extracts have protective effects against neurodegenerative conditions.  Research has shown that they help prevent the accumulation of beta-amyloid, a protein associated with Alzheimer’s disease.

Pomegranates possess over three times the antioxidant potential of red wine and green tea

Pomegranates owe much of their potent disease-fighting powers to their extraordinary antioxidant capabilities.

The juice of a single pomegranate contains more than 40 percent of the RDA of vitamin C – itself a potent antioxidant and immune system booster.  Pomegranates are also rich in beneficial amino acids, polyphenols, and anthocyanins, natural pigments that give the pulp an intense scarlet color.  These colorful flavonoids also contribute to pomegranate’s ability to scavenge free radicals and prevent oxidative damage in cells and tissues.

And, wait, there’s more good news about pomegranates: no side effects or adverse changes have been reported – even in a clinical study in which participants received 1,420 mg a day of pomegranate fruit extract.

However, the researchers noted that pomegranate could interact with certain prescription drugs.  Before supplementing with pomegranate extracts, consult a trusted holistic healthcare provider.

You can consume pomegranates in various beverages – such as juice or tea – or nibble the luscious seeds out of hand as a snack.  Pomegranate extracts are also available in the form of capsules and tablets.

By rejuvenating fragile, indispensable cell mitochondria, pomegranate can help combat the muscle weakness and frailty often associated with aging – leading to a stronger, longer quality of life.

Sources for this article include:

NIH.gov
Ibtimes.com
Lifeextension.com
NIH.gov

 

Posted in Age, Antioxidant, Cancer, Food, Mitochondria | One Comment »

Posted by: | Posted on: January 24, 2025

Beat type 2 diabetes with the power of antioxidant-rich foods

Reproduced from original article:
https://www.naturalhealth365.com/beat-type-2-diabetes-with-the-power-of-antioxidant-rich-foods.html

by: | January 22, 2025

type-2-diabetes-how-the-right-diet-can-help(NaturalHealth365)  Type 2 diabetes, which affects well over 500 million people worldwide, has reached epidemic proportions.  Conservatively speaking, 1 in 10 U.S. adults has type 2 diabetes, and Western medicine offers little hope for healing this condition.  For example, does anyone really believe that taking insulin is the best way to resolve blood sugar imbalances?  (Hint: the solution can be found on your plate.)

This devastating condition shows no sign of slowing down anytime soon.  In fact, health experts predict that well over 600 million adults will develop diabetes by 2030.  As scientists continue to search for more effective methods of prevention and treatment, studies reveal that a diet high in antioxidants — such as fresh fruit, vegetables, and tea — significantly lowers the risk of type 2 diabetes.

Intelligent study reveals that type 2 diabetes can be avoided with the right kind of diet

Fruits and vegetables contain phytonutrients, or plant chemicals, known as flavonoids.  These natural compounds have powerful antioxidant effects, scavenging harmful free radicals and reducing the oxidative damage contributing to disease.

Extensive studies have explored the anti-diabetic benefits of individual antioxidants found in fruits and vegetables, but researchers took a slightly different approach to this study.  To get a more comprehensive view of the relationship between food and diabetes, they examined the benefits of an overall high-antioxidant diet.

The 15-year study, published in Diabetologia (the journal of the European Association for the Study of Diabetes), involved over 65,000 women between the ages of 40 and 65.  Researchers analyzed questionnaires filled out by participants and found that the women with the highest amounts of antioxidants in their diets enjoyed a 27 percent reduction in risk of type 2 diabetes – a very substantial benefit.

The scientists reported that the odds of developing diabetes diminished as antioxidant consumption increased.  They noted that antioxidant capacity may play an important role in reducing the risk of diabetes in middle-aged women.

In other words – consistently making a series of simple, healthy dietary choices can dramatically lower the risk of a potentially life-threatening and costly disease.

The secret to success: Antioxidants work – at a molecular level – to fight diabetes

The study is not the only research showing the amazing effects of dietary flavonoids.

Researchers at the Harvard School of Public Health found that blueberry anthocyanins significantly lower the risk of type 2 diabetes.

In a study published in Nutrition and Metabolism, researchers set out to evaluate the biological action and therapeutic potential of dozens of dietary flavonoids and anthocyanins – and concluded by stating unequivocally that the phytochemicals protected against diabetes.

The team reported that flavonoids combat diabetes by helping to maintain blood glucose levels, promoting glucose uptake, and stimulating insulin production from the pancreas’s beta cells.

In addition, flavonoids improve the performance of fat-burning enzymes, decrease LDL cholesterol, and reduce levels of pro-inflammatory cytokines such as interleukin.  They significantly raised levels of a pair of antioxidants and disease-fighting enzymes, such as superoxide dismutase and glutathione.  They also helped to decrease advanced glycation end products.  AGEs are toxins that can trigger and worsen diabetes.

The list of anti-diabetic benefits from flavonoids is truly stunning.  It is hard to believe that an ordinary apple or a bowl of blueberries can harbor this type of disease-fighting therapeutic potential – but scientific research has shown it to be true.

Fresh fruits and vegetables offer a rich bounty of flavonoids

Virtually all fruits and vegetables are good sources of antioxidant flavonoids.  And these compounds have a synergistic effect – meaning they complement and potentiate each other’s powers.

Apples, grapes, and onions are rich in the flavonoid quercetin, while citrus fruits contain the flavonoids hesperidin, tangeritin, kaempferol, and naringenin.

Cruciferous vegetables such as broccoli and kale contain kaempferol and luteolin.  At the same time, blueberries and other purplish-blue plant foods are your best bet for obtaining anthocyanins, beneficial plant pigments with anti-diabetic effects.  Anthocyanins are also found in cranberries, cherries, blackberries, currants, raspberries, mulberries, purple grapes, red cabbage, and eggplant skins.

Orange vegetables, such as carrots and squash, contain healthy amounts of beta-carotene.

Keep in mind: fresh fruits and vegetables tend to be high in vitamin C, a potent antioxidant.  They are also naturally high in dietary fiber, which can help ward off the obesity that contributes to diabetes.

Enlist fresh, organic fruits and vegetables as your “first line of defense” against diabetes

The roster of foods that can help you fight diabetes is extensive – and delicious!

In addition to the foods already listed, flavonoid-packed fare to put on the menu includes plums, prunes, walnuts, strawberries, parsley, celery, onions, peppers, eggplants, green leafy vegetables and hazelnuts.

Antioxidant-rich beverages include teas – black, green, chamomile – red wine (in moderation), and coffee, which has been shown in studies to protect against type 2 diabetes.

Naturally, it would be best to choose organic varieties to avoid unwanted exposure to toxic chemicals – used in the growing process of most commercial brands.

Experts recommend eating fruits and vegetables raw, lightly steamed, or sautéed for maximum antioxidant benefits.  However, since the antioxidant capacity of carrots and celery increases when they are lightly cooked, steaming them is a smart choice.

Researchers have long reported that diets high in fruits and vegetables are strongly associated with a lower risk of developing heart disease and cancer – the two leading causes of death in the United States.  Now, thanks to the latest studies, we know that putting fresh fruits and vegetables on the menu can also help us fight another deadly disease.

Sources for this article include:

NIH.gov
Sciencedaily.com

 

Posted in Antioxidant, Diabetes, Food | No Comments »

Posted by: | Posted on: October 31, 2024

The Neuroprotective Benefits of Berberine


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2024/10/23/berberine-and-neurological-health.aspx

Analysis by Dr. Joseph Mercola     October 23, 2024

berberine and neurological health

STORY AT-A-GLANCE

  • Berberine is a plant-derived alkaloid with powerful neuroprotective properties, acting through antioxidative, anti-inflammatory, and antiapoptotic pathways. It’s able to cross the blood-brain barrier, directly impacting neural tissue and enhancing cognitive function
  • Early studies reveal berberine’s impressive effects on brain health, demonstrating enhanced memory and learning capabilities in animal studies and protecting neurons from oxidative stress and inflammation
  • Berberine acts as a “master switch” for brain cells, activating AMPK for efficient energy use, inhibiting acetylcholinesterase to boost memory, and enhancing dopamine levels for improved mood and cognition
  • Research shows berberine’s advantages against neurodegenerative diseases like Alzheimer’s and Parkinson’s; it also aids in stroke recovery. Berberine reduces plaque formation, protects neurons and promotes faster healing
  • More research is needed to maximize berberine’s brain-protective benefits. Scientists are exploring enhanced formulations, conducting human trials and investigating side effects and long-term safety

With the rising prevalence of conditions like Alzheimer’s, finding effective ways to protect your brain health is more important than ever. Current treatments for neurodegenerative disorders often fall short, leaving patients and their families desperate for better options. That’s where berberine comes in.

A plant-derived alkaloid with neuroprotective properties, berberine shows promise in helping fight and protect against neurodegenerative diseases. Its ability to act through multiple mechanisms, including antioxidative, anti-inflammatory and antiapoptotic pathways, sets it apart from many other plant-based compounds.1

I’ve been following the research on berberine closely, and the results are quite fascinating. Studies have shown that berberine crosses the blood-brain barrier, directly impacting neural tissue. This means it’s able to reach the areas of the brain most affected by neurodegenerative processes.2

Research has also shown that it enhances cognitive function and overall brain health, which is particularly important as we age. Protecting your mental faculties becomes increasingly crucial during your senior years, and berberine offers a promising avenue to help keep your mind sharp.

Early Studies Reveal Berberine’s Impressive Effects on Brain Health

Berberine’s long history in traditional Chinese and Ayurvedic medicine has caught the attention of modern scientists.3 Initial observations in laboratory settings provided evidence on its impact on neurological function. Animal studies also demonstrate berberine’s remarkable effects on cognitive performance, and test subjects displayed enhanced memory and learning capabilities, outperforming their untreated counterparts in various cognitive tests.4

Indeed, berberine packs a powerful punch when it comes to protecting your brain cells. This compound helps fight oxidative stress, which damages neurons over time. It also boosts your brain’s natural antioxidant defenses, creating a shield against harmful free radicals. This matters because oxidative damage plays a big role in conditions like Alzheimer’s disease.

Berberine also tamps down inflammation in your brain that wreaks havoc on delicate neural tissue. Berberine helps calm this inflammatory storm, modulating key signaling pathways that would otherwise contribute to brain cell death.5

Perhaps most interesting is berberine’s ability to protect neurons from programmed cell death, or apoptosis. This process, while normal in some cases, goes into overdrive in neurodegenerative diseases. Berberine inhibits excessive apoptosis, preserving vital brain cells that would otherwise be lost.6

A crucial factor in berberine’s effectiveness is its ability to cross the blood-brain barrier, meaning it directly reaches the areas where it’s needed most, making it a promising candidate for treating various brain disorders.7

These multiple layers of protection make berberine a fascinating subject for neuroscience research. Its diverse actions suggest its usefulness in tackling complex brain diseases from several angles at once.

Berberine Acts Like a Master Switch for Your Brain Cells

When it reaches your brain cells, berberine turns on the AMP-activated protein kinase (AMPK), which is like the energy manager for your neurons. When AMPK is activated, it helps your brain cells use energy more efficiently and stay healthy. This is important because brain cells use high amounts of energy; keeping them well-fed helps them work better and live longer.8

In addition, berberine inhibits acetylcholinesterase. This enzyme normally breaks down acetylcholine, a chemical that helps your brain cells communicate with each other. By slowing down this enzyme, berberine helps keep more acetylcholine around, which boosts your memory and cognitive skills.9

Berberine also boosts your levels of important neurotransmitters like dopamine, which is crucial for mood, motivation and cognitive function. By fine-tuning your dopamine levels, berberine helps keep your brain in a happy, focused state.10

Your brain cell’s powerhouses, the mitochondria, also benefit from berberine. This compound helps these tiny energy factories work more efficiently, which is crucial for keeping your neurons healthy and firing on all cylinders. Having well-functioning mitochondria means healthier, more resilient brain cells.11

Lastly, berberine has an epigenetic effect, meaning it influences which genes your brain cells turn on or off. Think of it this way — berberine helps your neurons read their instruction manual better. By tweaking gene expression, berberine helps your brain cells adapt and respond to stress more effectively.12

All these actions together make berberine a useful compound to help manage your brain health. It’s not just doing one thing — it’s like a Swiss Army knife for your neurons, helping them in multiple ways to stay healthy, energized and protected against damage.

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Berberine Offers Hope for Neurological Health Improvement

Berberine’s impact on reducing neurodegenerative diseases is significant. By protecting neurons from damage and improving cognitive function, it helps maintain your quality of life, even as you reach your senior years.

Berberine’s ability to support brain health offers a promising avenue for extending not just your lifespan, but your “brainspan” as well — the period of cognitive vitality. This could transform how you approach retirement, lifelong learning and social engagement in your later years.

In addition, berberine opens up new avenues for drug development in neurology. Pharmaceutical companies are now exploring ways to harness its neuroprotective properties, which could lead to a new generation of drugs that are more effective and have fewer side effects than current options for neurological conditions.13

The increased interest in natural compounds for neurological health sparked by berberine research is reshaping the field. It’s part of a broader shift towards exploring plant-based medicines and nutraceuticals. This trend encourages a more holistic approach to brain health, integrating traditional wisdom with modern scientific understanding.

Berberine Shows Promise Against Alzheimer’s and Other Neurological Conditions

Berberine’s neuroprotective effects are making waves in research on several brain disorders. For example, studies indicate that berberine has therapeutic benefits against Alzheimer’s disease through multiple mechanisms. These include reducing beta-amyloid production, inhibiting tau hyperphosphorylation, and modulating neurotransmitter systems involved in cognitive function.14

Scientists have observed improvements in memory and cognitive function in animal studies. This suggests berberine might help both prevent and treat Alzheimer’s symptoms.15,16,17,18

Parkinson’s disease is another area where berberine shows promise. Studies indicate it protects dopamine-producing neurons, which are the cells that die off in Parkinson’s. By keeping these cells alive, berberine helps slow the progression of this disorder.19

Stroke recovery is yet another field where berberine is making an impact. Berberine has shown promise in protecting against neurological impairments and blood-brain barrier disruption following intracerebral hemorrhage. One study demonstrated that berberine treatment reduced brain edema, improved neurological function, and preserved blood-brain barrier integrity in a mouse model of intracerebral hemorrhage.20

These findings paint an exciting picture of berberine’s uses across a range of neurological conditions. But it’s important to note that most of this research is still in early stages. While animal and cell studies are promising, we need more human trials to fully understand how berberine might be used in clinical settings. Here’s a summary of berberine’s actions in different neurological conditions:

  • Alzheimer’s disease — Reduces plaque formation and improves cognitive function
  • Parkinson’s disease — Protects dopamine-producing neurons
  • Stroke recovery — Reduces brain damage and promotes faster healing
  • General neuroprotection — Fights oxidative stress and supports overall brain health

More Research Is Needed to Maximize Berberine’s Brain-Protective Benefits

Scientists are using cutting-edge techniques to unlock berberine’s full advantages for brain health. For example, in vivo imaging allows researchers to observe berberine’s effects unfold in real time inside living brains, so they are able to better understand how the compound interacts with neural tissue and impacts brain function.21

Meanwhile, electrophysiological studies measure the electrical activity of neurons exposed to berberine. These tests show how the compound influences the way brain cells communicate and function. By observing changes in neural signaling, researchers are able to pinpoint exactly how berberine supports healthy brain activity.22

However, large-scale human clinical trials are still needed to validate these findings and determine optimal dosing and administration methods for maximum brain benefits.

Developing enhanced berberine formulations is another key focus. Scientists are exploring ways to improve its bioavailability, allowing more of the compound to reach the brain. This could involve creating novel delivery systems or combining berberine with other substances that boost its absorption.

Investigating side effects and long-term safety is essential as berberine moves closer to clinical use. While generally considered safe, more extensive studies will ensure its appropriate use for various neurological conditions. This research will help establish guidelines for different patient groups and identify any possible interactions with other medications.

Combination therapies incorporating berberine with existing treatments offer exciting possibilities. By pairing berberine with current Alzheimer’s or Parkinson’s medications, researchers hope to enhance overall efficacy and reduce side effects. This approach could lead to more comprehensive treatment strategies for complex neurological disorders.

Berberine Is a Natural Ally Against the Cognitive Effects of Aging

Berberine offers a natural approach to maintaining sharp minds well into your later years. This natural compound demonstrates remarkable neuroprotective properties through multiple mechanisms, including combatting oxidative stress, reducing inflammation and protecting neurons from premature death.

The multifaceted actions of berberine on the brain suggest it aids in healthy aging by preserving cognitive function and neuronal integrity. As scientists continue to unravel berberine’s mechanisms of action, we move closer to harnessing its full advantages for preventing and treating brain disorders. So, stay informed about this exciting field of research — it holds promise for revolutionizing how we approach brain health and neurological care.

Posted in Age, Antioxidant, Brain, Diabetes, Inflammation | No Comments »

Posted by: | Posted on: August 25, 2024

Ginseng’s Secret Language: How Plant miRNAs Speak to Human Cells

© GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC.
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Reproduced from original article:
https://greenmedinfo.com/content/ginsengs-secret-language-how-plant-mirnas-speak-human-cells
Written By: GreenMedInfo Research Group

This article is copyrighted by GreenMedInfo LLC, 2024

Imagine a world where plants can directly communicate with our bodies at a molecular level, fine-tuning our physiological processes. This isn’t science fiction – it’s the fascinating reality of cross-kingdom regulation through microRNAs, with ginseng leading the charge in this botanical-human dialogue.

The Silent Conversation: miRNAs as Cross-Kingdom Messengers

In the intricate dance of life, species have long been known to interact and support one another. However, recent discoveries in the field of molecular biology have unveiled a new layer to these relationships – one that operates at the genetic level through microRNAs (miRNAs). These small, non-coding RNA molecules play a crucial role in regulating gene expression, and remarkably, they can traverse the boundaries between kingdoms.

Ginseng: A Master of Cross-Kingdom Communication

Ginseng, revered for centuries in traditional medicine, has emerged as a prime example of a plant capable of cross-kingdom communication via miRNAs. Recent studies have shown that ginseng-derived miRNAs can survive mammalian digestion and enter circulation, where they interact with our cells and influence various physiological processes.1] This remarkable ability of ginseng miRNAs to cross species boundaries and directly impact mammalian and therefore presumably human physiology opens up new avenues for understanding the molecular basis of ginseng’s therapeutic effects.

Key Human Processes Modulated by Ginseng miRNAs

1. Immune Function

Ginseng miRNAs, particularly miRNA156, have been found to modulate immune responses in humans. They can influence the production of cytokines and the activity of immune cells, potentially explaining ginseng’s reputation as an immune-boosting herb.

2. Energy Metabolism

Research has shown that ginseng miRNAs can affect key enzymes involved in glucose metabolism and energy production. This may contribute to ginseng’s reported effects on fatigue and endurance.

3. Antioxidant Activity

Certain ginseng miRNAs have been observed to upregulate antioxidant enzymes in human cells, offering a molecular explanation for ginseng’s antioxidant properties.

4. Cardiovascular Health

Studies suggest that ginseng miRNAs may influence genes involved in blood pressure regulation and vascular health, aligning with traditional uses of ginseng for cardiovascular support.

The Broader Implications: A Web of Interspecies Support

The discovery of cross-kingdom regulation through miRNAs offers a new perspective on why diverse ecosystems tend to be healthier and more resilient. When plants and animals support one another, they may be engaging in a complex exchange of genetic information that fine-tunes the physiology of all participants.

This interspecies dialogue through miRNAs could explain:

  • Why diverse diets tend to promote better health
  • The importance of biodiversity for ecosystem and human health
  • The molecular basis for some traditional herbal medicines

Conclusion: Redefining Our Relationship with Nature

As we uncover the intricate ways in which species communicate through miRNAs, we are compelled to reconsider our relationship with the natural world. The line between “us” and “them” becomes blurred, revealing a deeply interconnected web of life where genetic information flows freely between species. Ginseng, with its remarkable ability to modulate human physiology through miRNAs, serves as a powerful example of this cross-kingdom collaboration, hinting at the untapped potential of nature to support and enhance human health.

Posted in Antioxidant, Cardiovascular, Energy, Immunity | No Comments »

Posted by: | Posted on: May 28, 2024

Glutathione: Meet the master antioxidant for optimal health

Reproduced from original article:
https://www.naturalhealth365.com/glutathione-meet-the-master-antioxidant-for-optimal-health.html
by: | May 25, 2024boost-glutathione-levels(NaturalHealth365)  Researchers and scientists have dubbed it “the master antioxidant,” “the body’s premier antioxidant,” and even “the mother of all antioxidants.”  And, no matter how complimentary the labels, glutathione richly deserves any of them.

This indispensable antioxidant helps to neutralize toxins in the body, eliminate dangerous free radicals, detoxify the liver, and support the overall functioning of the entire immune system.  Today, we’ll take a closer look at this powerful substance and, more importantly, how to boost glutathione levels within the body.

Glutathione is produced naturally by the body – but levels fall with age

Researchers have known of glutathione since 1889, but it is only over the last thirty years that they have begun to understand and explore its functions.

A small protein molecule, glutathione, is synthesized in the body from three different amino acids: L-cysteine, L-glutamic acid, and glycine.  Although it exists in every cell, the vast majority of glutathione is in the liver.

Glutathione regulates cell growth, fights the oxidation of circulating fats in the bloodstream, synthesizes and repairs DNA, helps to transport amino acids in and out of cells and has a whole arsenal of detoxifying and immune-boosting effects.

Unfortunately, glutathione levels begin to fall at midlife and can plummet as low as only 50 percent of what the body needs for optimal health.  In addition to aging, low glutathione can also result from overconsumption of heavily processed foods, environmental toxins, drugs, illness, infections, and stress.

Low glutathione levels are linked with chronic health problems

Low glutathione levels inhibit cellular function, allowing dangerous free radicals to cause oxidative damage.  Oxidative damage caused by free radicals is at the root of many chronic health issues.

Now, researchers are finding that low levels of glutathione can cause free radical-induced degenerative conditions such as heart disease and cancer – respectively, the number one and number two killers in the United States.  Of course, other countries in the Western world show similar grim statistics.

In a study published in the New England Journal of Medicine, researchers found that heart disease patients with low blood levels of glutathione were 30 percent more likely to suffer a heart attack than those with optimal levels.

Other conditions linked to glutathione deficiency include autoimmune diseases, chronic fatigue syndrome, diabetes, Alzheimer’s disease, Parkinson’s disease, autism, arthritis, kidney failure, and liver disease – to name just a few.

Glutathione has major immune system-boosting and detoxifying effects

Glutathione plays such a major role in detoxification and immune system function that it is not altogether far-fetched to picture it as a dragon-slaying hero, rushing to battle and defeat toxins and pathogens wherever these threats may be found.

Glutathione must be balanced in lymphoid cells for the immune system to function properly.  Its cysteine molecule makes the reproduction of T-cells possible.  Glutathione also actively helps macrophages in the bloodstream fight off pathogens and bacterial invasions and detoxifies reactive oxygen radicals created by ultraviolet light radiation.

In addition, glutathione helps regenerate and recycle other important antioxidants, including vitamin C and vitamin E.

As the major detoxifying agent in the body, glutathione chemically transforms carcinogens, toxins, and drugs into unreactive, harmless compounds that can be eliminated without damaging cell DNA.  In the case of heavy metals such as mercury and lead, glutathione neutralizes them by binding with them.

How do I raise my glutathione levels?

Grapefruit, melons, peaches, spinach, and asparagus are good sources of glutathione.  These foods should be eaten raw and organic whenever possible.  Heating them will deplete their glutathione content.

However, as a protein, glutathione is quickly digested and broken down into individual amino acids.  In fact, several studies have shown that dietary intake alone may not be sufficient to increase circulating glutathione levels.

Experts say the best way to increase levels is to supplement with glutathione precursors – the amino acids your body uses as building blocks to produce glutathione.

Foods rich in cysteine – such as cage-free (pasture raised) organic eggs, unsweetened non-GMO whey protein made from non-denatured proteins, garlic, and onions – are excellent choices.  Foods that contain sulforaphane – organic cruciferous vegetables like cabbage, Brussels sprouts, and broccoli – can also raise glutathione levels.

As for supplementation, both N-acetyl-cysteine and alpha lipoic acid have been shown to improve glutathione levels in cases of deficiency.  Other substances that may help boost glutathione levels include curcumin, melatonin from dark cherries, milk thistle, and the mineral selenium.

Considering all the vital functions glutathione performs, it can be wise to boost glutathione levels to ensure that you have enough of this irreplaceable molecule.  Your body will thank you for it.

Sources for this article include:

NIH.gov
NIH.gov
ImmuneHealthScience.com
ImmuneHealthScience.com

Posted in Antioxidant, Food, Glutathione, Health, Liver, Supplements | One Comment »

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