Cancer
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Cancer is a word most people dread, but it only affects less than half of us. LeanMachine wants to be in the other half, and correct nutrition is the way to get there. Billions of dollars are spent on treatment drugs, but almost nothing is spent on prevention!
Appendix cancer explodes 400% in Gen X and millennials, doctors can’t explain why
Reproduced from original article:
https://www.naturalhealth365.com/appendix-cancer-explodes-400-in-gen-x-and-millennials-doctors-cant-explain-why.html
by: July 3, 2025
(NaturalHealth365)
A devastating new study has uncovered a cancer crisis that’s quietly ravaging younger generations while leaving medical experts scrambling for answers. Appendix cancer rates have exploded by 400% among millennials and Gen X, representing one of the most dramatic cancer increases ever documented
The research, published in the Annals of Internal Medicine, analyzed data from nearly 5,000 appendix cancer patients over 45 years and revealed a pattern that should alarm every young adult in America. People born between 1976-1984 showed cancer rates more than three times higher than those born in the 1940s. Those born between 1981-1989 had four times the cancer risk.
Cancer rates skyrocket while doctors stay silent
Dr. Andreana Holowatyj from Vanderbilt University Medical Center put it bluntly: “The rates and trends which we observed were alarming and worrisome.”
Appendix cancer remains relatively rare, affecting only 1-2 people per million annually. But the explosive increase among younger generations signals something deeply wrong. Unlike other cancers with screening protocols, there’s no way to detect appendix cancer until it’s often too late.
Most people discover they have appendix cancer by accident, usually during emergency appendix removal surgery. By then, it’s frequently spread throughout the abdomen.
Symptoms that fool everyone
Appendix cancer symptoms masquerade as everyday digestive problems:
- Abdominal pain that feels like appendicitis
- Bloating that won’t go away
- Nausea and vomiting
- General stomach discomfort
These vague symptoms are often dismissed as stress or poor diet. Most cases aren’t found until the appendix ruptures, spreading cancer cells everywhere. Half of all patients are diagnosed after the cancer has already spread.
The appendix was once considered useless. Scientists now know it plays a role in immune function, making this cancer surge even more troubling.
Nobody knows what’s causing this
What’s driving this cancer explosion? Researchers suspect environmental exposures during childhood are now showing up as cancer decades later.
Dr. Andrea Cercek from Memorial Sloan Kettering admits: “It’s probably some type of combination, something multifactorial, but we have not yet identified it.”
The prime suspects include:
Ultra-processed foods that became standard in Gen X and millennial diets during childhood. These foods potentially altered gut bacteria in ways that increase cancer risk years later.
Chemical exposure from pesticides, plastics, and industrial pollutants that have built up over decades. Younger generations faced higher chemical loads than any previous generation.
Chronic stress from economic instability, social media pressure, and lifestyle factors that suppress immune systems meant to catch cancer early.
Antibiotic overuse during childhood can permanently damage gut bacteria communities responsible for immune function.
This cancer surge isn’t happening alone
Dr. Holowatyj noted similar patterns across multiple cancer types: “We’re seeing some of these generational effects for cancers of the colon, the rectum, the stomach.”
Something is affecting entire generations, not just appendix cancer. Multiple digestive cancers are spiking in younger adults, suggesting a common cause that’s damaging the entire gastrointestinal system.
Whatever is driving appendix cancer rates higher is also compromising the body’s ability to prevent other cancers. This points to fundamental changes in our environment, food supply, or lifestyle that previous generations never experienced.
Fighting back when Western medicine has no answers
Younger adults can’t wait for researchers to figure this out. The cancer prevention strategies that worked for previous generations may not cut it anymore.
Your body has natural cancer surveillance systems, but they need support in today’s toxic environment.
Reduce inflammation through a balanced diet of real, organic food, effective stress management, and avoidance of toxic exposures. Chronic inflammation facilitates the growth and spread of cancer.
Support detox pathways so your body can eliminate the chemicals that may be fueling this cancer epidemic. Your liver, kidneys, and gut require extra support in handling the modern toxic loads.
Strengthen immune function through proper nutrition, sleep, and lifestyle choices. Your immune system is designed to find and kill cancer cells before they become problems.
Avoid processed foods that may be contributing to the generational cancer surge. Fresh, whole, organic foods don’t carry the same risks as heavily processed products.
The clock is ticking
The 400% increase in appendix cancer among younger generations is proof that something fundamental has changed in our world that’s making cancer more common than ever.
Since there’s no screening for appendix cancer, prevention becomes your only protection against this silent killer.
If you are ready to learn how to protect yourself from the environmental factors driving cancer rates through the roof, consider Jonathan Landsman’s Stop Cancer Docu-Class, featuring 22 leading cancer experts sharing breakthrough strategies for cancer prevention and immune system support. Discover which foods, nutrients, and lifestyle changes can help your body detect and eliminate cancer cells before they become life-threatening. Learn about the environmental toxins to avoid, early warning signs to watch for, and proven protocols for reducing cancer risk.
Sources for this article include:
Ultraviolet Blood Irradiation Revolutionized Medicine — Why Did It Disappear?
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/06/13/uvbi-revolutionized-medicine.aspx
Analysis by A Midwestern Doctor June 13, 2025
Story at-a-glance
- Natural light is an essential nutrient many of us lack within our bodies. When ultraviolet light is introduced into the bloodstream, remarkable health benefits emerge
- The dermatology industry created hysteria about benign sun-induced cancers while ignoring that deadly melanoma actually results from sunlight deficiency, not excess exposure
- Once ultraviolet blood irradiation (UVBI) was discovered in the 1930s, it produced miraculous results for patients on the verge of death and was quickly adopted by hospitals throughout America, demonstrating remarkable efficacy for a wide range of diseases
- To neutralize this competition, the American Medical Association published a doctored study that “debunked” UVBI, and it became a forgotten therapy. Russians and Germans recognized its value and have produced decades of research showing UVBI’s remarkable utility
- This article explores UVBI’s remarkable history, systematic suppression, and scientific foundation, demonstrating why this therapy represents one of medicine’s lost opportunities
I have attempted to make the case that we are routinely denied vital knowledge, treatment, and care to protect the interests of the medical industrial complex. For example:
- I’ve highlighted how unsafe pharmaceuticals make it to market because approval panels were stacked with people taking money from manufacturers (which was a tactic Anthony Fauci weaponized against America).
- I’ve discussed1 how the American Medical Association was taken over by unscrupulous businessmen who funded the association by promoting anything they were paid to (which is why there were so many AMA advertisements of doctors promoting smoking)2 while using the government to outlaw competing therapies.
- I’ve shown how American society has been separated from fundamental health requirements (e.g., sleep or sunlight), how damaging losing these is, and how far the marketing industry goes to ensure we never reclaim these basic health requirements.
This suggests that remarkable medical innovations exist that have been overlooked or forgotten. I will discuss one — ultraviolet blood irradiation (UVBI) — because there’s vast evidence for its use and unlike many other lost medical technologies, it’s still relatively accessible.
The Importance of Sunlight
A widely held view exists that sunlight (particularly its ultraviolet component) is dangerous and must be avoided. Remarkably, much of that came from a 1980s public relations campaign that the struggling dermatology profession used to rebrand themselves as cancer fighters by creating a hysteria about benign sunlight-induced cancers while downplaying that the deadly skin cancer, melanoma, actually results from a lack of sunlight.
Treating skin cancer is both straightforward and highly lucrative, making dermatology one of the most sought-after medical specialties.
Note: A 20 year prospective study of 29,518 Swedish women found that those who avoided sunlight were 130% more likely to die than women who had regular sunlight exposure.3 They were much more likely to develop various medical conditions (e.g., they were twice as likely to get cancer).
As such, I’ve attempted to shine light on the critical benefits we receive from sunlight, how many illnesses result from artificial lighting and a lack of sunlight, and that the same changes observed in plants and animals due to unhealthy lighting are also observed in humans (all of which is discussed here). Key points I covered there included:
- Unhealthy light causes and exacerbates cancers and significantly increases infection risk (particularly in livestock).
- Unhealthy light contributes to behavioral disorders (e.g., ADHD).
- Healthy lighting significantly increases the health, fertility, and productivity of domesticated animals.
- The circadian rhythm (which regulates sleep and healing) is heavily disrupted by unnatural lighting.
- Many biological structures are highly sensitive to specific light wavelengths, which is problematic because artificial lighting has narrow bands rather than a complete spectrum.
- Light plays a critical role in generating circulation and protecting blood vessels.
- Ultraviolet light is particularly critical for health. The most dramatic benefits of light therapies occur when appropriate UV light is administered to the body.
- Glass blocks essential UV light, so modern life prevents access to that light, creating widespread UV deficiency.
- Since skin has difficulty absorbing UV light, we receive much light through the eyes. When individuals wear glasses blocking sunlight from entering their eyes, health problems can ensue that resolve once addressed.
The major challenge with light therapies is getting light inside the body. Fortunately, methods have been developed to do this, producing remarkable results for over a century.
The History of Ultraviolet Blood Irradiation
One of the oldest “proven” therapies was having people bathe in sunlight. It was one of the few things that actually succeeded in treating the 1918 influenza.4 Prior to antibiotics, it was one of the most effective treatments for tuberculosis5 and was widely used for other diseases (e.g., erysipelas and mumps).6 One UVBI pioneer noted that low doses of externally applied UV light stimulated general resistance to infection in animals and humans.7
The medical field concluded that part of sunlight’s value was that ultraviolet within it was a sterilizing agent, and UV devices were developed to sterilize things. For example, one of the most effective ways to prevent COVID-19 indoors was exposing air to UV light, and one promising approach explored for treating COVID-19 was safely putting UV light inside the respiratory tract to sterilize viral particles (which is what Trump was actually describing during his infamous disinfectant remark).8
Since blood-borne infections (septicemia) were a major problem, in 1927, Emmett K. Knott (who was not a doctor) decided to try sterilizing blood by extracting it, exposing it to UV light, and returning it to the body. Initially, when testing this by infecting dogs with lethal bacteria, he found that while treated dogs didn’t have bacteria in their blood at death, they still died after about a week.
Eventually, in 1928 an accident happened and Knott dramatically under-dosed a septic dog, after which the dog had a dramatic recovery — leading Knott to realize only a small amount of blood should be irradiated. Shortly after, Knott received a request from a doctor friend whose sister was dying from septicemia for blood irradiation. The UVBI treatment worked, and the woman made a complete recovery.
For five years, Knott refined his method without testing it on humans, likely due to the difficulty in finding willing doctors and the Great Depression. Eventually, in 1933, another Seattle doctor with a septic patient on the verge of death reached out to Knott, and again UVBI resulted in dramatic recovery.
Knott began traveling the country with his massive machine, and beginning in 1937, successfully convinced skeptical hospital doctors to use UVBI. As the therapy proved itself, more people adopted it, and by the 1940s, pioneering physicians who tested it on hundreds of patients found that UVBI consistently treated conditions such as sepsis, pneumonia (including viral pneumonias), kidney disorders, asthma, polio, botulism, rheumatic fever, and viral hepatitis.
UVBI almost always worked if administered early in the infection, often yielding miraculous results even when patients were on the verge of death, and significantly shortened hospital stays.
Note: Dr. George Miley, who had done the most UVBI work, commented on Knott’s work in 1940: “I think personally that this is one of the greatest contributions to medicine ever made by a citizen of the United States.”
By the early 1950s, UVBI was being used in approximately 50 American hospitals, with doctors reporting they had used it on thousands of patients and consistently seen immediate and miraculous results alongside a complete absence of side effects.
These doctors documented their work in a significant body of literature: 50 papers by 20 different authors (published in 18 different medical journals) covering over 3,000 patients with 36 different diseases — all finding remarkable UVBI benefits. UVBI was promoted in mainstream media (e.g., The New York Times9 and Time Magazine10).
Here’s one case from a physician who between 1938 to 1943 successfully treated over 400 patients with 35 different diseases using UVBI:11
“A patient had thrombosis of the cerebellar artery (brain blood clot), pneumonia, bacterial blood infection, lung emboli, leg blood clot, and paralysis of his left side and vocal cords — a hopeless and terminal case. When seen by Dr. Barrett, the patient was delirious and irrational, had eaten nothing except Coca-Cola for 11 days, and had lost 45 pounds.
He was immediately treated with UVBI and had an almost instant response. After a second treatment in three days, there was further dramatic improvement. Although it took several months, he recovered completely, regaining the 45 pounds he had lost and adding another ten. This patient would almost certainly have died within days without UVBI therapy.”
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Market Monopolization
At this point, the American Medical Association (AMA) became involved and attempted to extort Knott by offering to conduct a study validating UVBI for $100,000 (approximately $1 million today) and to purchase the rights to Knott’s device in return for a small sales cut.
After Knott refused (as did physicians across America advocating for UVBI), the AMA decided to do its study anyway. It was overseen by a friend of the AMA director (who was designing a competing device) and curiously, prior to being done, JAMA announced it was likely to fail.
The study had various issues (e.g., no one could inspect the machine, when returned they discovered a film had blocked UV light from reaching blood, it only had 68 test subjects, many cases were conditions UVBI wasn’t used for).12 Nonetheless, no adverse events occurred, no one died (despite many having dangerous conditions), and many patients experienced significant improvement. Despite this, the 1952 study concluded:13
“We have concluded that none of our patients derived benefit from the irradiation of blood with the Knott hemo-irradiator.”
Because of this “definitive study,” hospitals across America quickly abandoned UVBI and became fully committed to emerging antibiotics. Knott stopped producing his machine and died in 1961. The Salk vaccine also eliminated interest in finding polio treatments.
Note: Fortunately, UVBI revived in Russia, the former Soviet states, and Germany. Unlike America, these countries couldn’t afford extravagant medical spending and lacked routine censorship of scientific ideas that threatened the medical industrial complex. Operating on shoestring budgets, they were motivated to find economical disease solutions.
The most noteworthy aspect was that the exact same thing has been done to many other promising therapies. For example, around this time, the AMA approached the inventors of alternative cancer therapies (such as the Krebiozen, Hoxey and the Koch Catalyst) and pressured them to sign away almost all of the rights for the treatment to the AMA or be blacklisted.14
In each case, the inventor refused because they wanted it to remain affordable to everyday people, after which the AMA launched a blitz against the therapy,15 and then with the help of the FDA, buried it (which was later corroborated by a 1953 Congressional investigation).16 In short, because of the power the AMA wielded, a single fraudulent negative study could immediately erase large bodies of independent research showing otherwise.
As Pierre Kory details in “The War on Ivermectin,” this happened throughout the pandemic with unpatentable COVID-19 treatments.17 With hydroxychloroquine, the Lancet published a trial arising from overtly false data (later retracted) showing HCQ was killing people, leading to worldwide trial terminations.18
In contrast, numerous independent studies found HCQ was one of the safest and most effective COVID-19 treatments if used early, and prior to COVID-19, the “incredibly dangerous” HCQ was considered one of the safest and most essential medications in existence.
Note: Similar absurdities occurred with ivermectin and vitamin D (which for decades has proven more effective at preventing flu than annual flu shots).19
Paul Marik (widely considered the world’s top critical care expert)20 repeatedly demonstrated that IV vitamin C is transformative for sepsis when administered early, dramatically reducing death rates (e.g., his hospital’s sepsis death rate dropped from 22% to 6%,21 and in a study, from 40.4% to 8.5%).22 Yet this therapy was “debunked” because studies only gave IV vitamin C late in hospitalization (where it no longer works), making it nearly impossible to get IV vitamin C at American hospitals.
Note: During the early days of AIDS, Anthony Fauci suppressed lifesaving AIDS treatments while pushing a dangerous failed cancer drug that became standard AIDS treatment based on fraudulent studies.23
The costs of each of these are huge. Sepsis for example, is the third leading cause of death in hospitals and kills 350,000 Americans each year.24 Similarly, the primary cause of death from cancers is metastases, and many of the extreme approaches used to treat cancer are justified under the possibility that they might prevent a metastasis.
Likewise, COVID-19 being “incurable” cost our nation trillions of dollars and killed hundreds of thousands of Americans. Conversely, whenever an industry supported drug comes to market, it doesn’t matter how dangerous or ineffective its data shows it to be (e.g., the data for both the COVID-19 vaccines and remdesivir showed they had significant dangers and provided minimal benefit), a method will always be found to argue they are in fact extremely “safe and effective.”
Sadly, while awareness of UVBI’s miraculous properties has now largely disappeared thanks to the AMA’s control of the media, reports of it still emerge. For example, last year Joe Rogan and Jimmy Dore discussed how Trump discussing placing UV light inside the body to treat COVID was misconstrued as “injecting bleach” and how the AMA erased this revolutionary therapy.
Types of Blood Irradiation
Various methods exist for getting light inside the body. In the classic approach, blood is removed, typically diluted, and then infused back, allowing it to pass through light (requiring IV parts made of quartz glass, through which UV light can pass).
German and Russian researchers developed alternative approaches — directly applying a laser onto surface blood vessels (e.g., behind the knee or under the tongue) or threading fiber optic cables into vessels and illuminating from inside. These approaches (collectively known as laser blood irradiation or LBI) have been found relatively equivalent,25 with LBI requiring more treatments.
A leading researcher determined LBI had more rapid effects and was better for bronchodilation and allergen hyposensitization,26 while UBI had more substantial bactericidal and anti-inflammatory effects. Two weeks after treatment, UBI typically obtained better microcirculation results than LBI.
Numerous studies demonstrate that LBI is effective for a wide range of medical conditions, with varying effects depending on the light wavelengths used. To quote a recent review paper about LBI use in Russia:27
Additionally:
- Unlike UVBI, LBI is not easily obtainable in the United States.
- Unlike UVBI, LBI can only apply one wavelength at a time (due to laser coherence needs).
UVBI Research Foundation
UVBI researchers have identified over 200 journal articles on UVBI and LBI published between 1934 and 2020, with a third viewable online. These studies consistently found a complete absence of side effects from UVBI.28 Conditions with evidence of UVBI efficacy include:
- Bacterial infections (sepsis, septic abortions, osteomyelitis, meningitis, tuberculosis, typhoid fever)29
- Viral infections (pneumonia, shingles, hepatitis, severe COVID-19, long COVID, polio, AIDS)30
- Cardiovascular disorders (heart attacks, angina, peripheral arterial disease, intermittent claudication, Raynaud’s, thrombophlebitis, high blood pressure, pulmonary hypertension)31
- Autoimmune disorders (rheumatoid arthritis, asthma, eczema, multiple sclerosis, transplant rejections)32
- Abdominal conditions (liver, biliary and gallbladder diseases, pancreatitis, disseminated peritonitis, kidney diseases)33
- Surgery (preventing post-operative complications, reducing death rates, accelerating recovery, treating postoperative ileus or burns)34
- Obstetrics and gynecology (male and female fertility, preventing miscarriages, preeclampsia, healthy babies, polycystic ovarian syndrome, pelvic inflammatory diseases)35
- Neurologic and psychiatric disorders (depression, schizophrenia, migraine headaches, poor cerebral blood flow creating tinnitus, foggy head or insomnia)36
Note: All of the studies for the above conditions are discussed and summarized in this article.
Vasogen — The Patent Solution
One major UVBI barrier is that it’s not patentable and cannot justify the immense costs of clinical trials and lobbying for FDA approval. In the 1990s, the Canadian company Vasogen attempted to solve this problem by creating a device that mixed ozone, UVBI, and heat within its proprietary device, then injected it into the gluteal muscle.
This proprietary approach (deemed “irrational” by a leading ozone researcher)37 performed significantly worse than other methods but still produced remarkable results, resulting in Vasogen raising 225 million dollars, conducting over 60 studies over 8 years, demonstrating safety, securing over 24 patents, and publishing a successful Phase II trial for chronic heart failure and peripheral vascular disease.38
Unfortunately, due to a poorly designed Phase III trial (which had benefits but failed to achieve statistical significance), Vasogen went bankrupt.39 Few now know the company existed or that costly required Phase I and Phase II studies for UVBI have already been done.
Additionally, in 2015, AVIcure Bioscience published a Phase II safety study for UVBI,40 and in 2019, it published a successful Phase III clinical trial.41 Both trials showed safety for all patients and efficacy for the majority. Unfortunately, these studies on hepatitis C were conducted, and simultaneously, effective pharmaceutical treatments for hepatitis C hit the market, eliminating interest in alternative approaches.42
Remarkably, despite all this evidence and widespread usage for nearly a century, UVBI is still called “fringe” or “pseudoscientific” therapy with “no evidence,” illustrating why those terms are meaningless.
Note: The key requirement of the 2018 Right to Try Act is that Phase I safety studies have been completed.43
Conclusion
The UVBI story represents a forgotten side of medicine — a safe, effective, affordable therapy that could have saved millions of lives was systematically buried to protect pharmaceutical profits. Despite overwhelming evidence from hundreds of studies and thousands of successfully treated patients over nearly a century, UVBI remains marginalized in American medicine.
The pattern — initial enthusiasm, remarkable results, systematic suppression through fraudulent studies, eventual marginalization — has been repeated with countless promising therapies. From hydroxychloroquine and ivermectin during COVID-19 to IV vitamin C for sepsis, the medical establishment consistently employs the same playbook to eliminate competition to expensive pharmaceutical interventions.
Yet UVBI persists, quietly helping patients in integrative medicine practices across America and openly studied in countries like Russia and Germany. The therapy Dr. George Miley called “one of the greatest contributions to medicine ever made by a citizen of the United States” continues demonstrating remarkable potential for those fortunate enough to access it.
Understanding this history reveals fundamental corruption within our medical system — a system that prioritizes profits over patients and consistently suppresses safe, effective treatments that threaten pharmaceutical revenues. Only by recognizing these patterns can we begin to reclaim the remarkable healing potential that has been stolen from us.
Author’s Note: This is an abridged version of a longer article about UVBI which goes into greater detail on the mechanisms behind UVBI, summarizes its vast body of published literature, and provides resources for those interested in accessing the most effective forms of this therapy (something many have now reported benefitting from). That article and its additional references can be read here.
A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD’s exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD’s work, be sure to check out The Forgotten Side of Medicine on Substack.
- 1, 2 A Midwestern Doctor, April 21, 2024
- 3 J Intern Med. 2016 Oct;280(4):375-87
- 4 Am J Public Health. 2009 Oct;99(Suppl 2):S236–S242
- 5 J R Coll Physicians Edinb. 2017 Sep;47(3):276-280
- 6 Finsen, Niels Ryberg. Phototherapy. Arnold, 1901
- 7 Anesthesiology. Vol. 3. No. 4. LWW, 1942
- 8 Adv Ther 38, 4556–4568 (2021)
- 9 The New York Times, June 10, 1940
- 10 Time Magazine, June 13, 1949
- 11, 34, 35 Amazon, Into the Light: Tomorrow’s Medicine Today
- 12, 13 J Am Med Assoc,1952 Jul 26;149(13):1180-3
- 14, 15 Amazon, Politics in Healing: The Suppression and Manipulation of American Medicine
- 16 99 Cong. Rec. A5350 1953 (Archived)
- 17 Amazon, War on Ivermectin: The Medicine that Saved Millions and Could Have Ended the Pandemic
- 18 The Lancet, Volume 0, Issue 0
- 19 Amazon, Miller’s Review of Critical Vaccine Studies: 400 Important Scientific Papers Summarized for Parents and Researchers
- 20, 21 Justus R. Hope, January 14, 2024
- 22 Chest. 2017 Jun;151(6):1229-1238
- 23 A Midwestern Doctor, June 8, 2024
- 24 NIH, Sepsis
- 25 The Internet Journal of Laserneedle Medicine. 2013 Volume 3 Number 1
- 26 Amazon, Healing Photons: The Science & Art of Blood Irradiation Therapy
- 27 Journal of Lasers in Medical Sciences 8(2):56-65
- 28 Invisible Cure, List of UBI Studies
- 29 The American Journal of Surgery, Volume 57, Issue 3, 493-507
- 30 Russian Journal of Infection and Immunity. 2021, Vol. 11, N. 6, P1152-1158
- 31, 33 The Foundation for Blood Irradiation, Inc. (1933-1997) (Archived)
- 32 Medical Clinics of North America, Volume 24, Issue 3, 1940, Pages 723-732
- 36 Laser Blood Illumination. The Main Therapeutic Techniques. – M.–Tver: Triada, 2018. – 64 p
- 37 December 2008 International Journal of Cardiology 139(3):304-5
- 38 Journal of the American College of Cardiology, Volume 44, Issue 6, 2004, Pages 1181-1186
- 39 Journal of Cardiac Failure, Volume 12, Issue 9, 763
- 40 Int J Infect Dis. 2015 Aug:37:58-63
- 41 Cogent Medicine, 6(1)
- 42 Healthline.com, April 15, 2019
- 43 S.204 – Trickett Wendler, Frank Mongiello, Jordan McLinn, and Matthew Bellina Right to Try Act of 2017
High-Fat Diets Increase Breast Cancer Risk and Metastasis
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/05/27/high-fat-diets-breast-cancer-risk-metastasis.aspx
Analysis by Dr. Joseph Mercola May 27, 2025
Story at-a-glance
- Eating a high-fat diet (defined as 60% of daily calories) significantly increases your risk of developing breast cancer and accelerates the disease’s spread throughout your body
- High-fat foods activate your platelets, making them overly sticky, which helps cancer cells attach and grow rapidly in vital organs like your lungs
- Unhealthy fats, commonly found in processed foods and fast food, trigger harmful inflammation and hormonal imbalances that directly fuel breast cancer
- Making simple dietary shifts, such as cutting down on processed foods and vegetable oils, dramatically reduces your breast cancer risk and supports healthier cell function
- Regularly choosing whole, nutrient-dense foods and healthy carbohydrates helps your body lower inflammation, balance hormones, and create an environment less conducive to cancer growth
Breast cancer, characterized by lumps in the breast, unexplained swelling, skin changes, and sometimes persistent pain, remains the second most common cancer among women worldwide. In the U.S. alone, the American Cancer Society estimates that 316,950 women will be diagnosed with this disease in 2025.1
While it’s commonly believed that breast cancer occurs due to factors such as gene mutations or inherited genes, research shows that there’s one alarming factor that dramatically influences risk — your diet. Specifically, eating a diet excessively high in fat.
A High-Fat Diet Makes Cancer Spread Faster
A study published in Nature Communications2 explored how a high-fat diet speeds up the spread of breast cancer, particularly focusing on the role played by platelets, which are blood cells involved in clotting. Specifically, the researchers set out to determine the link between 60% of calories as fat and faster cancer metastasis (the spreading of cancer cells) into the lungs.
• A high-fat diet had a significant effect on platelet activation — Platelets in mice fed a diet consisting of 60% fat did not behave normally. They became excessively sticky and aggressive, and began forming clumps, especially in the lung tissues.
• Aggressive platelets didn’t just randomly cluster — These cells specifically released a protein called fibronectin, which significantly enhances the cancer cells’ ability to stick to blood vessels. Fibronectin acts like glue, providing cancer cells with a firm grip onto blood vessel walls.
Without fibronectin, cancer cells would struggle to latch onto the blood vessels in the lungs, severely limiting their potential to invade and spread. But when fibronectin levels are elevated, as it happens with high-fat diets, cancer cells easily attach, survive, and rapidly proliferate in new areas.
• Fibronectin damages cellular health — To confirm how pivotal fibronectin was, the researchers conducted an additional test — they blocked fibronectin’s action. In doing so, they dramatically slowed cancer spread, emphasizing how damaging a high-fat diet can be by ramping up fibronectin production.
• Reversing the harmful effects is doable — When the researchers switched the test mice from a high-fat diet back to a normal one, they noticed a significant reduction in platelet activation and cancer spread.
The change didn’t take long, showing that dietary adjustments provide rapid and powerful protection against metastasis. It’s a convincing reason to take immediate action, especially if you’re constantly consuming high-fat meals.
• Blood coagulation provides a clue to cancer risk — Another observation was related to blood coagulation times. Blood from the animals on high-fat diets coagulated faster — a change that accurately predicted worse outcomes. Essentially, faster blood-clotting indicates platelet hyperactivity, making your bloodstream a more hospitable environment for cancer cells.
By monitoring blood clotting times, health care providers can identify individuals at greater risk of aggressive cancer spread due to dietary factors, enabling earlier and more targeted interventions.
• The mechanism of platelet hyperactivation is closely linked to dietary fats — As noted earlier, activated platelets secrete high amounts of fibronectin, setting the stage for cancer metastasis by enhancing cancer cell adhesion to the blood vessels and lung tissues. But there’s another mechanism at play — they also shield cancer cells from your immune system.
Normally, your immune cells patrol your bloodstream, identifying and eliminating rogue cancer cells. However, these clumped platelets form a protective barrier around cancer cells, making them practically invisible to immune surveillance. As a result, cancer cells survive longer, multiply rapidly, and spread more efficiently throughout your body.
• Obesity compounds the risks of a high-fat diet — According to the researchers, having excess weight worsens the metastasis:
“As well as affecting primary BC [breast cancer] tumor growth, obesity enhances the metastasis of these cells to the lungs in a manner that is dependent on neutrophils, involving vascular dysfunction and increased endothelial transmigration of the tumor cells.
Moreover, obesity also induces chronic inflammation, while enhancing pro-thrombotic signaling in both platelets and endothelial cells, and promoting a state of hypercoagulability in cancer patients.”
Other Research Supports the Link Between Fat Intake and Higher Breast Cancer Risk
In a similar study published in Cureus,3 researchers conducted a meta-analysis to determine whether diets high in fat directly influence the risk of breast cancer in women. They chose eight studies from various countries, that involved large and diverse sample sizes, ranging from groups as small as 172 up to 91,779 people.
Each of the selected studies measured dietary fat intake among participants using food questionnaires and tracked breast cancer diagnoses through medical records confirmed by histology or radiological methods. Just like the Nature Communications study, the findings were clear for this one — high dietary fat significantly increased the risk of developing breast cancer.
• High polyunsaturated fat (PUF) intake is harmful — The study identified PUFs, particularly omega-6, as particularly detrimental. As noted by the researchers:
“[O]verall caloric intake has a larger impact on the development of obesity, which is linked to redox and hormonal abnormalities that promote tumor proliferation …
[E]xcess oxidative stresses may activate many transcription factors, including those that control the expression of genes implicated in pro-inflammatory pathways. The effect of polyunsaturated fatty acids (PUFAs) on cancer risk has been shown to depend on the ratio of -6 to -3 PUFAs. In vivo findings demonstrated that -6 PUFAs stimulate tumor development, while -3 PUFAs are protective.”
• Timing and duration of fat consumption influence cancer risk — Researchers noted that consistent consumption of high-fat foods over several years markedly amplified the risk. In other words, prolonged exposure to these dietary fats created cumulative damage, increasing the likelihood of breast cancer diagnosis later in life.
• The underlying biological mechanisms of fat intake on cancer — Excess fat consumption elevates your body’s levels of harmful substances called reactive oxygen species (ROS). These are unstable molecules that cause oxidative stress in cells, leading directly to DNA damage and cancerous changes.
Chronic oxidative stress doesn’t just damage individual cells — it sets off a chain reaction of inflammatory reactions, activating genes known to drive breast cancer growth.
• High intake of unhealthy fats disrupts hormone levels — The researchers noted that excess body fat tissue actively produces estrogen, and elevated estrogen levels strongly correlate with breast cancer development, especially in postmenopausal women. The estrogenic activity accelerates breast cell growth. Thus, consuming high-fat diets also indirectly amplifies the body’s own hormonal environment.
Just like the previous study, this research makes it clear that the amount of fat you put on your plate each day influences your risk of breast cancer. Reducing dietary fats, particularly those that trigger chronic inflammation and hormone imbalances, like omega-6 fats will improve your risk of developing breast cancer.
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Reduce Your Breast Cancer Risk by Changing Your Diet
To reduce your risk of breast cancer, addressing the root cause — your diet — is necessary. As shown in the studies, eating a high-fat diet sets the stage for inflammation, hormone imbalances, and aggressive cancer growth.
I recommend you take immediate action today to reverse the risks mentioned and build a healthier future. Here are my five strategies that will set you on the right path:
1. Cut back on linoleic acid — Linoleic acid (LA) is a harmful type of fat commonly found in vegetable oils and processed foods, as it promotes inflammation that fuels cancer growth. Start checking labels carefully and avoid foods containing soybean oil, corn oil, sunflower oil, safflower oil, and ultraprocessed foods.
Choose healthier fats like grass fed butter, ghee, or tallow instead, as these fats do not contribute to inflammation and help protect your cellular health. For more information on how LA causes cellular damage, read my article “Linoleic Acid — The Most Destructive Ingredient in Your Diet.”
2. Moderate your fat intake — As the earlier research noted, high levels of fat are strongly linked to breast cancer, but completely eliminating fat is neither realistic nor healthy — the key is moderation. Aim for dietary balance, because your body still needs fat to function properly.
For metabolic efficiency, aim for a daily fat intake of about 30% of daily calories, and ensure they come from healthy sources, including full-fat raw dairy, which is a primary source of the essential odd-chained fat C15:0. Glucose is the preferred fuel for your cells, so those should make up the bulk (45% to 55%) of your calories.
3. Switch to whole, nutrient-dense foods — If you’re regularly eating processed or fried foods, now’s the right time to make a change. Swap out processed meals and snacks for natural, nutrient-dense whole foods.
Good choices include fresh vegetables, fruits, pasture-raised meats, wild-caught seafood, pastured eggs, and raw, grass fed dairy. These foods provide essential nutrients that support your immune system and promote optimal health.
4. Optimize your carb intake for healthy cells — Your cells rely heavily on carbohydrates for energy, so severely restricting carbs is not a good idea. Instead, choose healthy carbohydrates to fuel cellular energy without triggering inflammation.
Whole fruits (with pulp), cooked root vegetables, and easily digestible sources like white rice will provide stable, beneficial carbohydrates. These carbs support balanced hormone levels and reduce the oxidative stress that feeds cancer growth.
5. Get regular exercise — Supporting your healthy diet by adding regular exercise is an effective way to protect your health against cancer. Research shows that higher muscle strength and cardiovascular fitness reduced all-cause mortality by 31% to 46% across different cancer types and stages.4
Now, what kind of exercises are good for you? The best, and easiest one, you can do right away is go for a walk outside — aim for 10,000 steps a day. If you’re doing strength training, the sweet spot is around 40 to 60 minutes per week.
Any longer than that, your longevity becomes the same as if you weren’t exercising at all. For a more detailed explanation on this topic, read my article “Physical Fitness Strongly Linked to Improved Cancer Survival, Study Shows.”
Frequently Asked Questions About the Link Between High-Fat Diets and Breast Cancer
Q: How does a high-fat diet influence the spread of breast cancer?
A: A high-fat diet dramatically accelerates metastasis of breast cancer cells by altering platelet behavior. Platelets become hyperactive and release fibronectin, a protein that helps cancer cells stick to blood vessel walls and invade other organs, especially the lungs. This dietary pattern also leads to faster blood clotting, which predicts more aggressive cancer progression.
Q: Can changing my diet reduce breast cancer risk?
A: Yes, dietary changes rapidly and significantly reduce cancer risk. Research shows that switching from a high-fat to a whole-food diet with an emphasis on carbohydrates as cellular fuel decreases platelet activation and fibronectin production, reducing the likelihood of cancer cells from spreading.
Q: What types of fats are most harmful when it comes to breast cancer?
A: Polyunsaturated fats (PUFs), especially omega-6 fatty acids found in vegetable oils (like corn, soybean, and sunflower oil), are particularly dangerous. They promote oxidative stress, hormonal imbalances, and chronic inflammation — all factors that contribute to tumor growth and metastasis. While omega-3 is beneficial for overall health, moderation is required because even too much healthy fats won’t be good for you.
Q: How does obesity interact with dietary fat to affect breast cancer?
A: Obesity exacerbates the harmful effects of a high-fat diet. It leads to chronic inflammation, vascular dysfunction, and increased blood clotting, all of which support cancer metastasis. Obese people also experience hormonal imbalances, particularly increased estrogen levels, which fuel breast cancer cell growth, especially after menopause.
Q: What are the recommended steps to reduce dietary risks for breast cancer?
A: To lower your risk, follow the recommendations below:
•Avoid vegetable oils — Take note of products containing soybean, corn, safflower, and canola oil.
•Keep fat intake below 30% of daily calories — Look for healthy, animal-based fats like ghee or grass fed butter. Coconut oil is also recommended.
•Eat whole, unprocessed foods — Examples include vegetables, fruits, and raw, grass fed dairy.
•Focus on healthy carbs — Dietary recommendations include root vegetables and white rice.
•Exercise regularly — Aiming for 10,000 steps per day and 40 to 60 minutes of weekly strength training.
The Immune System Is Your Body’s Defense Against Cancer
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/05/25/immune-system-bodys-defense-against-cancer.aspx
Analysis by Dr. Joseph Mercola May 25, 2025
Story at-a-glance
- Cancer is affecting younger individuals more than before. There’s even a case wherein a 13-year-old has developed metastatic pancreatic cancer
- Inflammation plays a central role in cancer development, with poor diet, environmental chemicals, and persistent viral infections contributing to immune system suppression
- The COVID-19 jab contributes to cancer risk through persistent inflammation from spike proteins
- Your immune system, particularly T-cells and natural killer cells, is crucial for fighting cancer
- Practical preventative measures include eating whole foods instead of processed foods, reducing chemical exposure, maintaining proper sleep, and avoiding mRNA shots
Cancer was once viewed as a disease that rarely surfaced in younger individuals, but today, that assumption no longer holds. So, what makes the current cancer trend so alarming? This, along with other topics, was discussed by Dr. Patrick Soon-Shiong, a surgeon and businessman, in an interview with Tucker Carlson, featured above.1
Most arguments about cancer center on genetic predisposition or external carcinogens like cigarettes. That conversation has merit, but it misses a key piece of the picture — your body’s own immune defenses. The bigger story involves strengthening the body’s protective mechanisms, and avoiding repeated hits to those defenses that allow cancer cells to take hold.
Investigating the Root Cause
Younger individuals once escaped the worst forms of cancer, but that has changed. Soon-Shiong tells the story of a case of a 13-year-old with metastatic pancreatic cancer, which in the past was basically unheard of. A growing body of clinical observation suggests that these cancers progress faster than older standards would predict, prompting doctors to label them “turbocharged” tumors.
• Inflammation is at the root of cancer — In Soon-Shiong’s words, your body “must inhibit the thing called P53 … and protect your body from … cancer. And if it persists and causes inflammation and inhibits P53, it begins to have the hallmarks of an oncogenic virus.”
• The rise of modern diets contribute to cancer — Soon-Shiong noted that ultraprocessed foods and other toxins keep a person’s gut in disarray. That scenario can worsen the immune system’s struggles. Excess linoleic acid from canola, soy, or similar oils triggers chronic inflammatory signals in many individuals.
These signals disrupt the cellular environment that NK cells and T-cells need for normal function. Meanwhile, diets that rely on refined sugar and cheap filler starches can further undermine metabolic health, though the problem runs deeper than sugar alone.
• Manmade chemicals in the environment also contribute to cancer — These include PFAS, red dyes, pesticide residues, and continuous exposure to microplastics and endocrine disruptors that hamper the body’s inherent defenses. Extra stress placed on immune cells can push them toward a suppressed state, giving malignant cells the opportunity to thrive.
Some interpret these trends as a perfect storm of poor nutrition, hidden toxins, and immunosuppression. Yet Soon-Shiong remains guardedly hopeful. He points to practical methods that hinge on T-cell function and a different approach to therapy. By focusing on the body’s innate ability to kill tumors, he believes more children and younger adults will be able to escape from this dreaded disease.
Is COVID-19 Altering Your Immune System in New Ways?
Soon-Shiong places part of the blame for rising cancer rates on persistent, chronic inflammation. His suspicion includes both COVID infections and the COVID jabs, wherein the virus’ spike protein lingers in tissues well after an active infection has ended. That prolonged presence maintains a continuous inflammatory response, fueling immune dysregulation.
• Standard antibody-based COVID shots have not cleared the virus from the body — Soon-Shiong wonders if repeated boosters further embed these spike protein fragments. He believes the shot keeps your immune system busy without resolving the underlying threat.
• COVID-19 gets into every cell of your body — Soon-Shiong also noted that spike protein, either from infection or the COVID shot, penetrates all of your cells, including the cells lining your blood vessels. As he explains in the interview:
“It goes wherever you have the thing called the ACE2 receptor, which is in the blood vessels. So, wherever we have a blood vessel in your body, it’s where it’s going to go and it has an ACE2 receptor on that blood vessel. That’s where it can go because that’s the purpose of the spike protein — to penetrate, to hijack that ACE2 receptor and get into their cells.”
• Spike protein results in different adverse health events down the line — Once spike protein enters your body, that’s when different complications arise, depending on the tissues affected. According to Soon-Shiong:
“That’s why it gets in the pancreas. That’s why you have brain fog. It disrupts the blood vessels of the brain and causes mitochondrial dysfunction. It’s why in the colon, which is high in the GI tract, is a high ACE2 receptor [organ].
That’s why pancreas has a high ACE2 receptor where — that’s why you people have in the heart — you have dysfunction, you, you’ve seen young people have sudden heart attacks.”
• Viruses have caused cancer in other contexts — Hepatitis leads to liver cancer, while HPV can spark cervical and throat cancers. A suppressed immune system cannot remove these intruders. That same risk appears in the post-COVID era.
Individuals with persistent inflammation are more likely to see T-cells go dormant, as Soon-Shiong described. The body basically loses its first responders against malignant transformation, whether the intruder is an outside virus or a mutated cell from within.
In the interview, Soon-Shiong goes deeper into the topic of cancers stemming from viruses due to inflammation, so I highly recommend listening to the whole thing. He concludes:
“What we know about virally induced cancers is well established. We know that if you get hepatitis, you get liver cancer. Hepatitis is a virus infection. We know if you get human papillomavirus, HPV, you get cervical cancer … If you get HIV, you get Kaposi sarcoma …
We call that oncogenic viruses in medical terms, meaning viruses that are … carcinogenic. And the fundamental basis for that are threefold. The hallmarks of our oncogenic virus is one; it must persist.
And why? Because it continues to create inflammation. And … with inflammation you get suppression because your body’s trying to suppress it. It must inhibit the thing called P53 that’s in your body to try and protect your body from … cancer. And if it persists and causes inflammation and, and [it] inhibits P53, it begins to have the hallmarks of an oncogenic virus.”
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Your Immune System Is the Foundational Pillar Against Cancer
A typical complete blood count (CBC) includes measurements of white blood cells. However, many oncologists rarely track T-lymphocyte or NK-cell counts unless something extreme surfaces. That omission frustrates Soon-Shiong.
• Your immune system is key to fighting cancer — Soon-Shiong notes that T-cells and NK cells handle the main job of seeking and destroying aberrant cells. If those protective warriors vanish, standard treatments may buy time, but fail in the end.
“It’s … job is to kill … anything that threatens the body, whether you, the body has infection, if you have TB, you have HIV, if you have hepatitis, you have COVID. These cells are there to recognize these infected cells and kill it.
As you and I are sitting here today, our stem cells are growing in order to replenish parts of your body, your heart, you, if you didn’t have that, you wouldn’t have a heart at the age of 14. You need those stem cells. But mathematically, there are some cells that are transformed and your body recognizes that through these natural killer cells and kills it,” he says.
• Immune system cells protect your body from tumor growth — In Soon-Shiong’s words, your immune system cells are “nature’s first responder.” He continues:
“That’s how we are all protected, and we are [in] the state of equilibrium or balance. On the other hand, the moment either the tumor finds a way to hide from these cells, or your body’s, or the tumor causes these cells to be suppressed.
And that’s why I call this the suppressor cells. And there are certain cells in your body called Treg cells or myeloid-derived suppressor cells … that, when they get upregulated, you’ve lost your protection.
And so, the question then is, how do we understand this balance? How do we increase the killers and how do we decrease the suppressors?”
• Traditional cancer treatments only provide short-term results — Chemotherapy and radiation, which often crush immune cells, produce a short remission in many. “But then, so often you watch it roaring back,” Soon-Shiong says.
That’s because the protective cells died along with the original tumor. The correct approach, he says, involves subtle stress on the tumor to expose it, followed by immunological activation to finish the job.
• Teach your own body to create a “bioshield” — Soon-Shiong references a product he’s currently developing called “BioShield.” While it is injected into your body, it’s not a vaccine, but rather a training mechanism for your immune system cells, which will help purge cancer cells from your body. He explains:
“A tumor has molecules that is foreign to the rest of your body. And if you educate your T-cell, you recognize as molecules that is foreign to the rest of your body that T-cell can remember. Now you have a memory T-cell … We now have bladder cancer patients who have lost their bladder in complete remission for nine years …”
While BioShield looks promising, it’s unlikely to be a magic bullet against cancer. That’s why Soon-Shiong stresses that cancer is all about your immune system. If your immune system is in top shape, your risk for cancer will be significantly reduced.
Practical Ways to Strengthen Your Body’s Defenses
To lower your cancer risk, start addressing what’s weakening your immune system in the first place. Inflammation, toxins, stress, poor food choices, and lack of sleep aren’t just small issues — they are the main reasons why your body fails to spot and destroy cancer cells. Here are my recommendations:
1. Clean up your diet and eat more whole foods — If you constantly rely on frozen dinners, fast food, or packaged snacks, it’s time to shift. Aside from being nutritionally lacking, these are loaded with dyes, additives, and inflammatory vegetable oils that confuse your immune system.
Swap them out with fresh produce, grass fed meats, and whole ingredients you recognize. Cook meals at home and store them in glass or stainless steel instead of plastic.
2. Cut your exposure to harmful chemicals — If you are a parent, office worker, or anyone constantly touching printed receipts, using fragranced cleaners, or microwaving in plastic, you are surrounded by chemicals that disrupt your immune cells. These chemicals don’t just sit on the surface — they enter your bloodstream and quietly weaken your immune defenses.
3. Spend enough time outdoors and get sufficient high-quality sleep — If your schedule has you staying up late, glued to screens, or skipping daylight, your immune system isn’t recharging.
Go outside each morning for natural light — it resets your body clock. Sleep at the same time each night in a cool, dark room for seven to nine hours at a consistent schedule. Even missing just an hour or two of deep sleep affects your immune system’s ability to function at its best.
4. Don’t get the COVID shot — If you already got the shot, don’t get any more boosters or mRNA gene therapy shots. Following this strategy immediately ends the assault on your body. But if you’ve already developed a shot-related injury, the next section contains more in-depth tips.
Other Strategies to Help Address COVID-Related Injuries
If you or a family member is suffering from long COVID or adverse effects from the shot, know that there is still hope for recovery.
• Protect your health with these protocols — I recommend you go over the I-RECOVER program by the Front Line COVID-19 Critical Care Alliance (FLCCC). It provides extensive information about how to treat long COVID2 and post-vaccine injuries.3
• Get rid of electromagnetic fields (EMFs) in your home — In addition to the measures discussed by the FLCCC, I recommend reducing your EMF exposure in your home. Research has shown that manmade sources, such as your Wi-Fi router and 5G towers “can disturb the homeostasis of free radicals leading to dysfunctions such as the ‘cellular stress response.'”4
• Minimize linoleic acid (LA) intake — Your fat intake matters because your mitochondria contain cardiolipin, which influences mitophagy and overall mitochondrial quality control.
To promote proper cardiolipin function, boosting omega-3 fat intake is important while simultaneously cutting back on omega-6 fat. However, don’t make the mistake of eating too much omega-3, as eventually it will cause the same damage as eating too much omega-6. For a more detailed explanation on this balance, read “Linoleic Acid — The Most Destructive Ingredient in Your Diet.”
• Optimize your vitamin D level — This nutrient plays an important role in supporting your immune system. Research shows that low vitamin D levels are linked to an increased risk of cancers.5 Vitamin D attaches to the vitamin D receptor in your cells, creating a cascade of signals that affect how cancer cells grow, develop, and survive.6 Studies have also confirmed that vitamin D helps prevent respiratory infections, including COVID-19.
I recommend raising your vitamin D level to a range between 60 ng/mL and 80 ng/mL. To know if you’re hitting that range, you need to get tested. For more information about the benefits of vitamin D for cancer, as well as tips on how to optimize it properly, read “More Evidence Showing Vitamin D Combats Cancer.”
Frequently Asked Questions About the Immune System and Cancer
Q: Why is cancer affecting younger people more than before?
A: According to Dr. Patrick Soon-Shiong, the increase in cancer cases among children and young adults is a result of immune system damage caused by chronic inflammation, poor diet, environmental toxins, and lingering effects from COVID-19 infections or shots. These cases often involve rapidly progressing “turbocharged” tumors that behave more aggressively than traditional cancers.
Q: What role does inflammation play in the development of cancer?
A: Inflammation is central to cancer’s progression. Chronic inflammation suppresses key tumor-suppressing proteins like P53 and compromises the immune system’s ability to eliminate cancerous cells. This persistent immune activation, sometimes from viral proteins like the COVID-19 spike protein, allows malignant cells to thrive by weakening the body’s natural defense mechanisms like T-cells and natural killer (NK) cells produced by your immune system.
Q: How do diet and environmental toxins increase cancer risk?
A: Modern diets high in ultraprocessed foods, refined sugars, and vegetable oils (like canola and soy) disrupt gut health and fuel systemic inflammation. Simultaneously, everyday exposure to manmade chemicals such as “forever chemicals,” food dyes, pesticides, and microplastics overwhelm the immune system. This perfect storm of poor nutrition and hidden toxins suppress immune cells, allowing tumors to escape detection and grow unchecked.
Q: How is COVID-19 linked to rising cancer risks?
A: Soon-Shiong theorizes that both COVID-19 infections and shots contribute to persistent inflammation and immune dysfunction. The virus (or spike protein from the vaccine) enters cells via ACE2 receptors found throughout the body — including the heart, brain, and pancreas — and disrupt mitochondrial function. Over time, this leads to increased risk of cancer.
Q: What strategies can strengthen the immune system and lower cancer risk?
A: Key strategies include:
• Eating whole, unprocessed foods to reduce inflammation
• Avoiding harmful chemicals in plastics, printed receipts, and fragranced products
• Improving sleep and natural light exposure to support immune regulation
• Reconsidering COVID-19 boosters, especially for those experiencing adverse effects
- 1 YouTube, The Tucker Carlson Show, March 27, 2025
- 2 FLCCC Alliance, Long COVID Treatment
- 3 FLCCC Alliance, Post-Vaccine Treatment Guide
- 4 Int J Mol Sci. 2020 Nov; 21(21): 8031, Role of CL in Mitochondrial Quality Control
- 5 The Journal of Steroid Biochemistry and Molecular Biology July 2023, Volume 231, 106308
- 6 Ageing Research Reviews June 2023, Volume 87, 101923, Introduction
Can Aspirin Prevent the Spread of Tumors? Researchers Say Yes
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/05/06/can-aspirin-prevent-the-spread-of-tumors.aspx
Analysis by Dr. Joseph Mercola May 06, 2025
STORY AT-A-GLANCE
- Aspirin helps prevent cancer metastasis by boosting your immune system’s T cells, which attack cancer cells that try to spread throughout your body
- Metastasis causes 90% of cancer deaths as cancer cells travel through blood or lymph systems to form new tumors in organs like lungs, liver or bones
- Aspirin blocks a substance in your body that normally slows down T cells, allowing them to move and attack cancer cells more effectively
- Low doses of aspirin (75 to 300 milligrams daily) appear effective, with benefits increasing after 5 to 7.5 years of regular use
- Willow bark is a natural alternative to aspirin; it contains a compound that your body turns into the same active ingredient as in aspirin
Did you know that a pill you likely already have in your medicine cabinet could help stop cancer from spreading? That’s right — aspirin, the little white tablet you pop for headaches or to keep your heart healthy, does more than you think. Scientists are discovering that aspirin could help your body fight cancer, especially when it tries to move to new places in your body.
This movement is called metastasis, and it’s what makes cancer so dangerous. In fact, metastasis is responsible for nine out of 10 cancer deaths.1 Finding a way to stop it could save lives — maybe even yours or someone you care about. It turns out aspirin boosts your immune system to fight cancer, leading researchers to suggest this familiar pill could become a cancer-fighting hero.
What’s the Sneaky Way Cancer Takes Over Your Body?
You might know cancer starts as a tumor, but what happens when it spreads? That’s metastasis, and it’s bad news.
• What’s metastasis? Metastasis is when cancer cells break away from the original tumor and travel through your blood or lymph system to form new tumors in places like your lungs, liver or bones. Picture dandelion seeds blowing in the wind — once they land, they grow anywhere. That’s how cancer spreads throughout your body.
• Why is metastasis so dangerous? Because it doesn’t just stay in one spot. It can attack multiple organs at once, making it much harder to treat. Worse, it often happens silently. You might not feel a thing until it’s spread too far, which is why stopping it early is so important. Cancer deaths are typically due to metastasis, not a solitary tumor.
• Your immune system tries to fight back — It has special cells called T cells that act like security guards, spotting and destroying those traveling cancer cells. But sometimes cancer outsmarts them. It’s like the guards get tied up, letting the intruders slip by. The good news is that aspirin helps untie those guards so they can win the fight.
How Can Aspirin Power Up Your Cancer Defenses?
You’ve probably taken aspirin for a headache or fever. Maybe your doctor even suggested it for heart health. But stopping cancer spread? That’s a twist many aren’t aware of.
• Aspirin does more than just ease pain — It calms inflammation, which is a hallmark of cancer.
• Here’s how aspirin works with your blood — Your blood has tiny cell fragments called platelets that help stop bleeding when you get a cut. But sometimes these platelets accidentally help cancer by surrounding cancer cells and hiding them from your immune system, like a disguise. Aspirin, especially in small doses, stops platelets from making a substance that interfere with your T cells.
• What’s this substance? Think of it as a roadblock holding up your T cells — those security guards we talked about. It slows them down, so they can’t chase cancer cells as well. When aspirin clears this roadblock, your T cells get moving again, ready to tackle cancer cells trying to spread.
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How Does Aspirin Boost Your Body’s Security Guards?
Let’s zoom in on your T cells. These are your body’s special forces, always patrolling to find and destroy cancer cells. They’re tough, but not invincible.
• Cancer’s sneaky move — Cancer releases a substance that dulls your T cells, like putting them to sleep so they can’t fight effectively.
• Aspirin fights back — Scientists found that aspirin stops this substance, waking up T cells to attack cancer cells more efficiently. In lab animals, this reduced cancer spread, with a 2025 Nature study showing fewer new growths.2 This suggests aspirin could keep your T cells sharp to prevent cancer spread.
Could Aspirin Be Your Cancer Shield?
So, what does this mean for you? Low-dose aspirin might help prevent cancer from spreading, especially if you’ve had early-stage cancer or it runs in your family.
• Aspirin keeps cancer spread at bay — Imagine adding aspirin to your health routine. It’s a simple step with big benefits.
• Aspirin works with vitamin C — Your body benefits even more when aspirin is combined with vitamin C, which also has antitumor effects. Studies have shown that this combination is more effective against cancer cells while remaining gentler on healthy cells compared to conventional chemotherapy drugs.3
• Aspirin dosage matters — Low doses of aspirin (75 to 300 milligrams (mg) per day) have been shown to be as effective as higher doses in reducing death from colorectal cancer, suggesting you don’t need large amounts to reap the benefits.4
• Consistency and long-term use seem to be key — Studies suggest the benefits of aspirin increase with long-term use. The most significant reductions in cancer risk occurred after five to 7.5 years of regular use.5
• How to select aspirin — Choose immediate-release aspirin formulations rather than coated extended-release versions to avoid unnecessary additives. Immediate-release aspirin is available on Amazon. Examine the inactive ingredients list carefully; ideally, corn starch should be the only additive listed.
Willow Bark Is a Natural Alternative
For those with aspirin sensitivity, salicylic acid or willow bark supplements are alternatives worth considering. When you take aspirin, your body changes it into a form called salicylic acid. This is what actually works to reduce pain and swelling, and to keep your blood from clotting too much. Willow bark is a natural source of this compound.
• Willow bark has been used for centuries — Across various cultures, willow bark has been relied upon for pain relief, fever reduction, inflammatory conditions, headaches and even wound healing. Ancient Egyptians, Hippocrates and Native American healers all recognized its medicinal properties, using it to treat ailments ranging from joint pain to skin rashes and digestive issues. Its long history of use suggests broad therapeutic potential.
• Willow bark is a natural alternative to aspirin — Willow bark stands out as the best natural alternative to aspirin because it provides similar pain-relieving and anti-inflammatory benefits while being gentler on the stomach.
Unlike synthetic aspirin, which isolates and modifies salicylic acid, willow bark contains a complex mix of compounds — including flavonoids and polyphenols — that work together to enhance its effectiveness and reduce potential side effects.
This natural synergy allows for a slower, more balanced release of salicin in the body, leading to fewer digestive issues compared to aspirin. For those looking to avoid synthetic drugs but still gain aspirin-like benefits, willow bark offers a time-tested, well-rounded alternative that works with your body rather than against it.
• Willow bark dosages — For those who are sensitive to aspirin or prefer a plant-based option, willow bark extract can offer a similar effect with the right dosage. While aspirin and willow bark share similarities, their metabolism differs, meaning the body processes them in unique ways. Common dosing guidelines for standardized willow bark extract (15% salicin) include:
◦ To approximate 81 mg of aspirin, take 400 mg to 800 mg of willow bark extract
◦ To approximate 111 mg of aspirin, take 500 mg to 1 gram of willow bark extract
The Bottom Line — Aspirin’s Role in Cancer Prevention
The idea that a simple, inexpensive pill could help prevent cancer from spreading is both promising and powerful. Research continues to highlight aspirin’s ability to support the immune system’s T cells, keeping them active against rogue cancer cells that try to take hold in new areas of the body.
For those looking to enhance their health strategy, low-dose aspirin appears to offer significant benefits — especially when used consistently over time. While aspirin isn’t a standalone cure, its ability to reduce inflammation, interfere with cancer’s sneaky tactics, and boost immune surveillance makes it a compelling option for those at risk.
If you’re considering adding aspirin to your routine, talk to your healthcare provider about the right dosage and any potential interactions. And for those who prefer a natural alternative, willow bark provides a plant-based way to tap into similar benefits.
Cancer prevention doesn’t always require cutting-edge treatments — sometimes, the solution might already be in your medicine cabinet.
FAQs About Aspirin and Cancer
Q: Can aspirin really prevent cancer from spreading?
A: Yes, research suggests that low-dose aspirin helps prevent metastasis, which is when cancer spreads to other parts of your body. It does this by helping your immune system’s T cells fight cancer cells more effectively.
Q: How does aspirin help the immune system fight cancer?
A: Aspirin stops a substance that slows down your T cells, letting them move and attack cancer cells better to keep cancer from spreading.
Q: What is the recommended dosage of aspirin for cancer prevention?
A: Low doses of aspirin, typically between 75 to 300 mg per day, have been shown to be effective.
Q: Are there any natural alternatives to aspirin?
A: Yes, willow bark is a natural option that gives your body something similar to what makes aspirin work. It’s useful if you’re sensitive to aspirin.
Q: How long does it take to see the cancer-fighting benefits of aspirin?
A: Studies suggest the most significant reductions in cancer risk occur after five to 7.5 years of regular aspirin use. Consistency and long-term use are key to maximizing the protective effects.
- 1, 2 Nature March 5, 2025
- 3, 4, 5 Cureus. 2024 Feb 21;16(2):e54658
Chemotherapy creates toxic chain reaction in healthy cells, new research reveals
Reproduced from original article:
https://www.naturalhealth365.com/chemotherapy-creates-toxic-chain-reaction-in-healthy-cells-new-research-reveals.html
by: April 25, 2025
(NaturalHealth365) When cancer patients receive chemotherapy, they’re rarely told about the biological “time bomb” being activated inside them – one that continues exploding long after treatment ends.
A new study published in BJC Reports has unmasked the hidden mechanism behind chemotherapy’s devastating long-term effects, revealing a truth far different from what oncologists have been telling patients.
The toxic cascade your doctor won’t discuss
When chemotherapy kills cells, it triggers something alarming: dying cells release dangerous fragments called “cell-free chromatin particles” (cfChPs) into the bloodstream. Unlike normal cell death, chemotherapy creates a tsunami of these toxic particles that overwhelm your body’s cleanup systems.
These particles don’t just disappear – they actively penetrate healthy cells throughout your body, damaging DNA and activating inflammatory pathways in organs far from the original tumor site. This explains why so many chemotherapy patients develop “secondary cancers,” cognitive impairment, heart damage, and immune dysfunction years after treatment.
Even more concerning, this damage accumulates with each treatment cycle. Every chemotherapy session creates a new flood of these toxic particles, which can remain active in the body for months, creating a compounding toxic burden that conventional medicine completely ignores.
The statistics they don’t share
The damage from chemotherapy’s toxic particles is extensive:
- Secondary leukemias appear in up to 6.8% of patients receiving certain chemotherapy agents
- Cardiac damage occurs in up to 26% of patients receiving anthracycline chemotherapy
- Permanent nerve damage affects 30-40% of patients receiving platinum-based chemotherapy
- Cognitive impairment (“chemo brain”) affects up to 75% of chemotherapy recipients
Until now, these side effects were attributed simply to direct drug toxicity. The discovery that many are caused by this secondary wave of cfChP damage – damage that continues long after treatment ends – should transform how we approach cancer care.
Yet this crucial information remains largely buried while patients suffer unnecessarily.
The solution Western medicine ignores
The most revolutionary aspect of this research is discovering that natural compounds can effectively neutralize these toxic particles, potentially preventing much of chemotherapy’s collateral damage.
Researchers identified a combination of resveratrol (found in grape skins) and copper that demonstrated a remarkable ability to bind to cfChPs and prevent them from entering healthy cells. Unlike pharmaceutical interventions, this natural approach works with the body’s own detoxification systems to neutralize the threat without causing additional side effects.
Other natural agents showing promise include:
- Quercetin: This flavonoid found in apples and onions helps stabilize cell membranes, making them more resistant to cfChP penetration.
- N-acetylcysteine: This powerful antioxidant helps replenish glutathione, your body’s primary defense against toxic compounds.
- Medicinal mushrooms: Compounds in reishi and turkey tail help modulate the immune response to cfChPs and support normal cell repair.
What makes these natural approaches especially valuable is that they don’t appear to interfere with chemotherapy’s anti-cancer effects – they specifically target the secondary damage while allowing the chemotherapy to still attack cancer cells.
What every cancer patient needs to know
If you or a loved one is facing chemotherapy, these findings highlight critical protective steps:
- Work with an integrative oncologist who understands both conventional treatments and evidence-based natural approaches.
- Time your protective agents properly – research suggests taking them in the days before and after treatment, not during chemotherapy itself.
- Support your cellular repair systems with compounds like sulforaphane (from broccoli sprouts) and ellagic acid (from pomegranates).
- Enhance elimination pathways through hydration, lymphatic drainage techniques, and targeted nutritional support.
- Monitor for delayed effects, particularly in vulnerable organs like the heart, brain, and bone marrow.
The bottom line: Knowing what to do can protect your health
The revelation that chemotherapy creates a cascade of damage through toxic cfChPs represents both a warning and an opportunity. The warning is clear: conventional cancer treatments may be causing far more extensive and long-lasting damage than patients realize.
The opportunity is equally significant: Much of this damage may be preventable with proper understanding and appropriate supportive strategies. Natural compounds represent a new frontier in protective oncology – one that focuses not just on killing cancer cells, but on preserving the health of the person fighting cancer.
Are you looking to protect your cells from cancer and the toxic effects of conventional treatments? Discover natural, science-backed strategies to support your body’s natural defenses against cellular damage.
Sources for this article include:
The hidden cost of CT scans: The cancer risk your doctor isn’t discussing
(NaturalHealth365) They seem harmless enough – quick, painless medical scans that let doctors see inside your body without surgery. But a new study just published in JAMA Internal Medicine has uncovered a staggering reality about CT scans that the medical establishment has been downplaying for years: the radiation from a single year’s worth of these common diagnostic tests could trigger over 100,000 future cancer cases.
While medical professionals often dismiss radiation concerns with vague reassurances, this groundbreaking research provides shocking numbers that should make every patient think twice before agreeing to that “routine” scan.
Consider the consequences: This is a RED ALERT about CT scans
The numbers are far worse than previously thought. In 2023 alone, Americans underwent more than 93 million CT scans – that’s 62 million patients being exposed to powerful ionizing radiation. Using state-of-the-art modeling, researchers from the University of California, San Francisco, now project that approximately 103,000 future cancer cases will develop over these patients’ lifetimes as a direct result.
Dr. Rebecca Smith-Bindman, who led this study across 143 U.S. hospitals and outpatient facilities in 20 states, found that the cancer burden from CT scans is now three to four times higher than previous estimates from 2009. The study analyzed detailed radiation dose data from more than 120,000 actual CT examinations, making it the most comprehensive analysis ever conducted.
The findings are particularly disturbing when broken down by cancer type and patient demographics:
- Lung cancer tops the list with 22,400 projected cases (21,400 in adults, 990 in children)
- Colon cancer follows with 8,700 cases
- Leukemia represents 7,900 cases
- Bladder cancer accounts for 7,100 cases
- Breast cancer in women contributes 5,700 cases
The risk is especially pronounced for children, with girls under one year of age developing cancer at a shocking rate of 20 per 1,000 CT scans – a risk magnitude that should give every parent serious pause.
The hidden culprits: Multiphase scans and unnecessary imaging
What many patients don’t realize is that “one CT scan” often isn’t just one exposure. Nearly 30% of scans are now “multiphase” procedures that deliver multiple rounds of radiation during a single exam, dramatically increasing cancer risk.
The UCSF researchers identified abdomen and pelvis CT scans as the greatest contributors to projected cancers, responsible for 37,500 cases (37% of all projected cancers) despite representing only 32% of all CT scans. These procedures often use multiple scan phases, resulting in substantially higher radiation doses.
Equally concerning is the 30% increase in CT usage since 2007, a growth the researchers attribute partly to the alarming rise in “low-value, potentially unnecessary imaging” – scans that provide little or no medical benefit but still deliver cancer-causing radiation.
The vulnerable: Children and women face greatest risk
While the per-scan cancer risk is highest in children, particularly infants, the vast majority of projected cancers (93,000 cases or 91%) will occur in adults simply because they receive more scans.
The study revealed striking sex differences as well. Women face significantly higher radiation-induced cancer risks than men, especially for lung and thyroid cancers. Even when researchers adjusted their models to be more conservative, lung cancer remained the most common radiation-induced cancer in women.
If current practices continue, the researchers warn that CT-associated cancers could eventually account for 5% of all new cancer diagnoses annually – putting CT scans on par with other major cancer risk factors like alcohol consumption (5.4%) and excess body weight (7.6%).
The medical establishment’s “acceptable risk” fallacy
For decades, medical professionals have downplayed radiation risks by invoking the “benefit outweighs the risk” mantra. But this study challenges that cavalier approach, especially considering that many CT scans are performed when safer alternatives work just as well or when no imaging is needed.
The researchers emphasize that their projections are actually conservative. They excluded CT-guided procedures like biopsies (which use higher doses), didn’t account for the potentially greater damage from CT’s low-energy x-rays compared to other radiation sources, and applied adjustments that assume lower radiation doses are less harmful per unit than higher doses – an assumption increasingly questioned by modern research.
Protecting your health: The Bottom Line
No doubt, CT scans have revolutionized Western medicine, but they are not without risk. If we continue down the current path, CT-induced cancers could soon rival other major, preventable causes of cancer.
We cannot afford to ignore this warning. As patients, we must advocate for thoughtful care. As clinicians, we must uphold the highest standards of safety. And as a society, we must embrace healthier lifestyles – not just to live better, but to reduce our dependence on tools that, when overused, can do more harm than good.
Bottom line: We, at NaturalHealth365, hope that this study will serve as a wake-up call to the value of living a healthy lifestyle.
Sources for this article include:
A Closer Look at the Anticancer Properties of Methylene Blue
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/04/19/anticancer-properties-of-methylene-blue.aspx
Analysis by Dr. Joseph Mercola April 19, 2025
STORY AT-A-GLANCE
- Methylene blue has been shown to shrink tumors and slow cancer growth by targeting cancer cell metabolism and energy production
- Photodynamic therapy with methylene blue uses light activation to destroy cancer cells while leaving healthy cells unharmed, making it a more precise treatment option
- Research on ovarian cancer found that methylene blue forces tumors to shift away from their preferred energy source, making them more vulnerable to treatment
- Unlike chemotherapy, methylene blue treatment does not cause significant side effects or toxicity, making it a promising option for patients with drug-resistant cancers
- Proper dosing is important. Just 5 milligrams of pharmaceutical-grade methylene blue per day is enough to reduce cellular stress and support mitochondrial health
Conventional cancer treatments often come with debilitating side effects. For example, chemotherapy and radiation therapy not only target tumors but also damage healthy cells, leaving patients weakened and vulnerable to infections. In an effort to find safer treatment options for patients, researchers are now testing the efficacy of methylene blue — a commonly used dye that enhances cellular energy production — in treating cancer.
Video Link
Methylene Blue Photodynamic Therapy Shrinks Tumors
A systematic review published in Frontiers in Pharmacology analyzed the effects of methylene blue in photodynamic therapy for cancer treatment. Researchers reviewed 10 preclinical studies from different countries assessing how methylene blue, when activated by light, impacts tumor growth.
• Methylene blue targets different cancers — The analysis covered different types of cancer, including colorectal tumors, melanoma and carcinoma, highlighting methylene blue’s ability to shrink tumors through a highly targeted mechanism that spares healthy tissue. A total of 133 mice were used, with 59 receiving methylene blue photodynamic therapy and 74 serving as untreated controls.1
• Antitumor properties of methylene blue — The researchers found that methylene blue significantly reduced tumor sizes in seven of the 10 studies, with reductions ranging from 12% to complete tumor elimination.
The largest effects were seen in colorectal cancer models, where tumors shrank by up to 99.9%, while some breast cancer models showed slower tumor progression rather than outright shrinkage. These results show methylene blue has strong anticancer effects, though its impact varies depending on tumor type and drug delivery method.2
• The use of light to fight cancer — Photodynamic therapy relies on methylene blue’s ability to absorb light in the 630 to 680 nanometer wavelength range. When exposed to this specific type of light, methylene blue generates reactive oxygen species (ROS), highly reactive molecules that destroy cancer cells from within.
This process selectively targets tumor cells because methylene blue accumulates in malignant tissue while sparing healthy cells. The review found that this light-activated destruction was particularly effective in skin and colorectal tumors, leading to significant tumor reduction within weeks of treatment.3
New Technology Improves Bioavailability of Methylene Blue
One of the most promising findings involved the use of nanotechnology to enhance methylene blue’s anticancer effects. Five studies included in the review used nanoformulations — tiny carriers designed to improve the drug’s stability and absorption.4
• Increased bioavailability — According to the researchers, the nano-based versions of methylene blue led to even greater tumor reduction than traditional injections. For instance, a breast cancer study using methylene blue-loaded nanoparticles resulted in complete tumor eradication.5
• Experiments in dosages — Tumor response also depended on the number of methylene blue treatments administered. While some studies used a single injection, others administered up to seven doses over time. More frequent treatments generally resulted in greater tumor shrinkage. For example, one carcinoma model that received seven doses showed significantly slower tumor growth compared to models that received only one or two doses.6
• Results are positive, but sometimes inconsistent — While methylene blue photodynamic therapy was effective in most studies, the review noted some inconsistencies. In a few cases, tumors did not shrink but instead grew more slowly than untreated tumors. This was observed in some breast cancer models, where tumor reduction was not as dramatic as in other cancers.
Researchers theorize that this variation is due to differences in how well methylene blue is absorbed in different tissue types. Some cancers may require modifications in dosing, delivery methods or additional combination therapies to enhance treatment effects.7
• Improved antitumor response — Beyond its ability to destroy cancer cells, methylene blue also helps enhance the immune system’s response to tumors. The meta-analysis shows that ROS generated during photodynamic therapy triggers immune activation, helping the body recognize and attack remaining cancer cells.
This immune-boosting effect likely explains why some tumors continued to shrink even after photodynamic therapy sessions ended. However, more research is needed to confirm this mechanism to help improve long-term treatment outcomes.8
• Safe to use — Methylene blue’s safety profile is another advantage noted in the review. Unlike chemotherapy and radiation, which cause widespread damage to healthy cells, photodynamic therapy with methylene blue resulted in minimal side effects in animal models.
The treatment selectively targeted cancerous tissue without causing significant harm to surrounding healthy cells, making it a promising option for patients who cannot tolerate conventional treatments. Additionally, methylene blue is relatively inexpensive, meaning it offers a more affordable alternative to expensive targeted cancer therapies.9
These findings reinforce methylene blue’s growing reputation as a powerful tool in cancer treatment. By leveraging light-activated therapy, this compound offers a way to precisely target tumors while minimizing damage to healthy cells.10
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Methylene Blue Disrupts Cancer Cell Metabolism
In an animal study published in Cancers, a team of Canadian researchers explored how methylene blue affects ovarian cancer growth at the metabolic level. The findings revealed that methylene blue significantly slowed tumor growth, and more importantly, targets cancer cell metabolism, altering how tumors generate energy and making them more vulnerable to destruction.11
• Methylene blue works as a chemotherapy adjunct — The researchers used an ovarian cancer model where human tumor cells were implanted into immunodeficient mice. These particular cells were resistant to carboplatin, a chemotherapy drug commonly used to treat ovarian cancer. This resistance is a major problem in real-world treatment, as many patients eventually stop responding to standard chemotherapy.
The study compared multiple treatment groups — mice receiving methylene blue alone, methylene blue combined with carboplatin, carboplatin alone and an untreated control group. Tumors in the methylene blue group grew significantly slower than those in the control and carboplatin-only groups, demonstrating its effectiveness even against drug-resistant cancer.12
• Cancer cell energy production is affected — Cancer cells thrive on a dysfunctional metabolism known as the Warburg effect, which prioritizes glucose fermentation over normal oxygen-based energy production. This metabolic switch allows tumors to grow rapidly and resist many treatments.
With this in mind, the study found that methylene blue disrupted this process, forcing cancer cells to rely on oxygen-based energy production again. This shift puts immense stress on the tumor cells, making it harder for them to survive and multiply.13
• Mitochondrial genes are targeted — Cancer cells treated with methylene blue had lower expression of key respiratory chain genes, particularly those involved in complex IV, which is responsible for oxygen reduction.
In other words, methylene blue interfered with the tumor’s ability to efficiently process oxygen, further disrupting its energy supply. This effect was much more pronounced in cancer cells than in normal cells, reinforcing methylene blue’s selective action against tumors.14
• Virtually nontoxic — Methylene blue did not cause noticeable toxicity in the test mice. Unlike chemotherapy, which often leads to severe side effects like weight loss and immune suppression, mice receiving methylene blue maintained stable body weight and showed no signs of distress.
This is a critical advantage, as one of the biggest challenges in cancer treatment is balancing effectiveness with patient quality of life. The ability to target tumors without causing widespread damage makes methylene blue an attractive option for future therapies.15
These findings provide strong evidence that methylene blue is not just a photodynamic agent but also a metabolic disruptor in cancer therapy. By forcing tumors to shift away from their preferred energy source, methylene blue makes them more vulnerable to treatment.16
Safety and Dosage Recommendations for Methylene Blue
Based on these findings, it’s easy to fall into the idea that “more is better” when it comes to taking methylene blue for your health. However, don’t fall into this trap. As mentioned in my interview with metabolic health expert Georgi Dinkov, getting the proper dose is important to avoid severe adverse effects. One example is serotonin syndrome — a fatal condition caused by excessive serotonin levels in the brain.
• Contraindications of methylene blue — It is a potent monoamine oxidase type A (MAO-A) inhibitor. This means that when it is combined with a selective serotonin reuptake inhibitor (SSRI) or other serotonergic drugs, your serotonin levels can increase to dangerous levels.
Methylene blue can interact with other medications, too, including other antidepressants and antimalarials, altering their efficacy or causing adverse reactions. In addition, methylene blue is contraindicated for people diagnosed with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to the risk of hemolytic anemia (a blood disorder wherein your red blood cells break down faster than your body can replace them).
• Your urine will turn blue — Be aware that methylene blue can stain your urine and occasionally, your tongue. While these effects are harmless, it will most likely surprise you when it happens.
• False pulse oximeter readings — High doses can also interfere with pulse oximeter readings, due to its light absorption properties, resulting in falsely low oxygen saturation readings.
• A note for those with kidney damage — If you have severe renal insufficiency, it would be wise to use methylene blue with caution and under close medical supervision as impaired kidney function influences how fast drugs clear from your system.
• Other side effects of methylene blue — Examples include mild and transient gastrointestinal discomfort, such as nausea and diarrhea. While rare, a wide range of allergic reactions, from skin rashes to life-threatening anaphylaxis, can also occur. Headaches and confusion have also been reported. Though less common, cardiovascular effects, such as increased blood pressure and palpitations, could also occur.
• Low doses are better — Methylene blue is better taken at small, daily doses, ranging from 5 to 15 milligrams (mg), according to Dinkov, especially for long-term use. This is the sweet spot for the diverse benefits of methylene blue without increasing your serotonin levels. High doses of methylene blue are generally reserved for therapeutic applications, and even then, it must be done under the supervision of a medical practitioner.
If you’re considering adding methylene blue to your health routine, consult with a knowledgeable medical professional first. Together, you’ll be able to work out the dosage specific to your needs, as well as warn you of potential harmful interactions with any medications you’re currently taking.
My Personal Way of Taking Methylene Blue
When it comes to buying methylene blue, you’ll find three types for sale — industrial-grade, chemical-grade (laboratory-grade) and pharmaceutical-grade.
• Buy pharmaceutical-grade methylene blue — Out of the three, the only one you should ever use is the pharmaceutical-grade variety, ideally in solid, capsule or tablet forms. Avoid liquid solutions of methylene blue as dissolving it in water significantly decreases its effectiveness after 48 to 72 hours.
• Don’t use methylene blue for aquariums — You’ve probably seen methylene blue used in maintaining aquariums. That’s because it contains antifungal, antiparasitic and oxygen-transporting properties. While those benefits also sound enticing for therapeutic usage, this type of methylene blue often contains additional harmful contaminants, even posing serious health risks to your aquatic pets.
Never use methylene blue designed for aquariums or other animal-related applications. To protect your health, always choose pharmaceutical-grade, as it undergoes rigorous testing to confirm it is free from impurities.
• Methylene blue will help with reductive stress — Remember not to over-rely on methylene blue to achieve optimal health. In my own case, I have eliminated my regular intake of methylene blue. I find that my daily walks by the ocean are incredibly helpful in managing reductive stress naturally.
However, during times when I’m unable to take a walk by the beach, I would consider taking 5 mg of methylene blue daily, adjusting to 3 mg if I were 75 pounds lighter in weight, and doing so six days a week.
If you’re considering taking methylene blue for its anticancer (or other metabolic) benefits, visit your doctor first to check if it’s suitable for your case. The reason for this is because the appropriate way to use methylene blue is through a prescription, and misuse will put your health at risk.
Frequently Asked Questions About the Anticancer Potential of Methylene Blue
Q: How does methylene blue help fight cancer?
A: Methylene blue works in two ways — photodynamic therapy and metabolic disruption. In photodynamic therapy, it accumulates in cancer cells and, when exposed to specific wavelengths of light, produces reactive oxygen species that destroy tumors while sparing healthy tissue. It also disrupts the altered metabolism of cancer cells, forcing them to rely on normal oxygen-based energy production, weakening and slowing their growth.
Q: What types of cancer have methylene blue been shown to affect?
A: Studies have demonstrated that methylene blue significantly shrinks tumors in colorectal cancer, melanoma and carcinoma. Research also shows that it slows the growth of chemotherapy-resistant ovarian cancer, making it a promising option for hard-to-treat cases.
Q: Is methylene blue safe to use as a cancer treatment?
A: Unlike traditional chemotherapy and radiation, methylene blue does not damage healthy cells. Animal studies have shown minimal toxicity, no severe side effects and a strong safety profile. However, pharmaceutical-grade methylene blue should always be used, and improper dosages or interactions with certain medications, like SSRIs, should be avoided.
Q: How is methylene blue taken for cancer therapy?
A: The most effective and safest method is pharmaceutical-grade methylene blue in capsule or tablet form, with a standard dosage of 5 mg once daily for mitochondrial support.
Q: Can methylene blue be combined with other cancer treatments?
A: Yes, research shows that methylene blue enhances the effects of chemotherapy drugs like carboplatin. It also strengthens the immune system’s response to tumors, which will help improve long-term outcomes. More studies are needed to determine the best combinations and dosing strategies for different cancer types.
- 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 Frontiers in Pharmacology, 14:1264961
- 11, 12, 13, 14, 15, 16 Cancers, 2024, 16(2), 355
How DMSO Naturally Eliminates Cancers
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/04/18/how-dmso-naturally-eliminates-cancers.aspx
Analysis by A Midwestern Doctor April 18, 2025
STORY AT-A-GLANCE
- Dimethyl sulfoxide (DMSO) effectively treats many ailments, including strokes, tissue injuries, autoimmunity, and a myriad of skin diseases and challenging infections
- DMSO’s unique properties also make it highly suited for both eliminating cancers and protecting the normal cells from cancer therapies
- Hundreds of studies have shown DMSO can transform a wide range of cancerous cells back into normal cells — something very few other agents are capable of
- DMSO strengthens the immune response to cancer and allows the immune system to recognize and permanently eliminate many different cancers that otherwise evade the immune system
- DMSO is directly toxic to cancerous cells and greatly increases the potency of a wide range of natural and conventional anticancer agents. This both increases cure rates and allows lower chemotherapy doses, significantly reducing their toxicity
DMSO is a naturally occurring substance that, when used correctly,1 safely, and rapidly improves a variety of conditions medicine struggles with — particularly chronic pain. For example, thousands of studies show DMSO treats a wide range of:
• Injuries such as sprains, concussions, burns, surgical incisions, and spinal cord injuries (discussed here).
• Strokes, paralysis, many neurological disorders (e.g., Down syndrome and dementia), and numerous circulatory disorders (e.g., Raynaud’s, varicose veins, or hemorrhoids), which were discussed here.
• Chronic pain (e.g., from a bad disc, bursitis, arthritis, or complex regional pain syndrome), which was discussed here.
• Many autoimmune, protein, and contractile disorders such as scleroderma, amyloidosis, and interstitial cystitis (discussed here).
• Head conditions including tinnitus, vision loss, dental problems, and sinusitis (discussed here).
• Internal organ diseases such as pancreatitis, infertility, liver cirrhosis, and endometriosis (discussed here).
• A wide range of skin conditions such as burns, varicose veins, acne, hair loss, ulcers, skin cancer, and many autoimmune dermatologic diseases (discussed here).
• Many challenging infections such as shingles, herpes, chronic ear or dental infections, and osteomyelitis (discussed here).
Sadly, once the FDA realized the extent to which DMSO would transform medicine, the agency made the decision to erase it from history. As a result, millions of patients who it helped and the thousands of studies on its therapeutic potential have been largely forgotten. Consider for example this 1980 60 Minutes program:
Fortunately, because DMSO is effective for a wide range of conditions, it’s caught on like wildfire over the last six months (e.g., I’ve already received over 2000 reports of remarkable responses to DMSO, many for a variety of “incurable conditions”2).
DMSO and Cancer
Because of the controversy surrounding DMSO, once its pioneers realized it also treated cancer, a decision was made to downplay this facet of DMSO as “unproven” cancer cures are always attacked by the medical system. As a result, DMSO’s anticancer properties still remain relatively unknown.
In the first part of this series, I presented dozens of studies that show DMSO effectively treats cancer pain (which is often very challenging to address) and dramatically reduces many of the complications experienced from radiation therapy and chemotherapy (as it selectively protects healthy cells from those agents).
Given how debilitating each of those can be for a cancer patient, it is remarkable DMSO has not been adopted for any of those applications, particularly since addressing those does not take business from the cancer industry (and if anything would make more patients want to undergo conventional cancer care).
Note: 65% of oncologists’ revenue comes from chemotherapy drugs3 (which coincidentally are by far the most profitable drug market4).
In this article, I will focus on how DMSO eliminates cancer.
Cancer Differentiation
At the start of life, the first cell can become anything, and as it divides, it becomes more specialized through a process called differentiation. This process is vital in medicine, especially with stem cells, which can replace damaged cells. Cancer, however, is a disease of dedifferentiation,5 in which normal cells lose their structure and begin dividing uncontrollably.6
As such, something that could differentiate cancer cells into normal cells would be immensely helpful in treating cancer. Unfortunately, conventional medicine only has one agent like that (all-trans retinoic acid which is only used for a fairly rare blood cancer7).
All of this began in 1971, when a virologist discovered that DMSO could induce differentiation in erythroleukemia cells at a 2% concentration, making most of them revert to normal cells.8 At higher concentrations, DMSO stopped growth and even killed cancerous cells (and was much less likely to kill mice than those injected with untreated cancer cells).
Following this, she published a variety of studies that mapped out how this process occurred, which agents suppressed or enhanced it. She showed that the differentiating effect persisted long after DMSO was no longer present.9,10,11,12 Her work in erythroleukemia was then repeatedly replicated (e.g., I’ve reviewed 62 corroborating studies,13 along with 95 more for the related cancer acute myelogenous leukemia14).
Note: DMSO’s ability to differentiate leukemic cells was so well recognized that in 1992, it was selected for a microgravity experiment on the International Space Station.15
By 1983, it was recognized DMSO could differentiate 12 different cancer types,16 and now this differentiating capacity has been repeatedly shown for each of the following cancers:
• Blood cancers — Acute promyelocytic leukemia,17 chronic myeloid leukemia,18 cutaneous erythromyeloleukemia,19 hairy cell leukemia,20 histiocytic lymphoma,21 Non-Hodgkin lymphoma,22 T-cell leukemia,23 T-cell lymphoma24
• Organ cancers — Bladder,25 brain,26 breast,27 colon,28 esophageal,29 intestinal,30 kidney,31 liver,32 lung,33 prostate,34 rectal,35 ovarian,36 stomach,37 thyroid38,39
• Other cancers — Embryonic carcinoma (into heart cells),40 fibrosarcoma,41 melanoma,42 nasopharyngeal,43 rhabdomyosarcomas44
Collectively, these studies showed:
• DMSO normally differentiated the cancer (it was rare for me to find studies where it did not) and did so in a dose-dependent fashion (e.g., 0.5% to 2% was often used45). At higher concentrations (e.g., 1.5%), those changes were often permanent.46
• Cancer growth, proliferation, and survival in tandem frequently decreased. In parallel, key tumor suppressing genes increased (e.g., P21,47 PTEN,48 and RB49), many cancer genes were suppressed,50 and the cancer cells were weakened (e.g., with transient DNA strand breaks) or induced into programmed cell death.51,52
As such, I believe it quite likely that if more cancer cell lines or specific cancer proteins and genes were tested, DMSO would demonstrate anticancer properties in those areas too.
Note: DMSO has also been repeatedly shown to prevent potent carcinogens from causing cancer.53,54,55
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Mechanisms of Differentiation
In addition to DMSO positively changing many factors associated with cancer (e.g., reducing cancer genes, increasing anticancer proteins and altering cancerous DNA) a few other mechanisms have also been identified by researchers.
First, tumor cells typically grow chaotically, but adding 1% to 2% DMSO led to a more organized structure resembling normal cells.56 Over four days DMSO caused melanoma cells to reorganize their cytoskeleton, halting their growth.57 Likewise, in another study, 1% DMSO significantly altered the cellular skeleton of melanoma cells but not regular cells:58
DMSO also affects other structural aspects of cancer cells:
• It shifts the cell membrane’s transition temperature making it more gel-like59 (a trait shared with other cancer differentiating agents60).
• DMSO caused disordered and tightly packed cancer cells to rearrange them themselves into an ordered parallel orientation like that seen in non-cancerous tissues.61
Note: Polar solvents besides DMSO can also both cause these changes and induce cancer cell differentiation, suggesting this is a fundamental component of the differentiation process.62
• DMSO shrank the cytoplasm of cancerous cells by 23% over nine hours.63
• DMSO increased the negatively charged phospholipid content in cancer cell membranes,64 enhancing fluidity and improving the cell’s zeta potential (a measure of its electrical charge that determines the tendency for things to clump together).
Collectively, many of these studies touch upon a longstanding observation that the transition to cancer is in part due to the electrical charges and the state of the water within the cells (e.g., it should be in an energy generating liquid crystalline state65 — something raising the membrane transition temperature promotes), which is a topic I have written more about here.
Additionally, DMSO also dissolves a barrier around cancer cells that prevented chemotherapy drugs from entering them66,67 and was found to make cytoskeleton target chemotherapies 30 to 1000 times more potent.68
Note: DMSO also allows chemotherapy to pass through the blood-brain barrier so that otherwise unreachable brain cancers can be exposed to chemotherapy.69
Pleomorphism
One of the forgotten schools of medicine is that microorganisms can assume different shapes (morphologies) and that particular morphologies can be highly detrimental to health. For example, previous pioneers of forgotten alternative cancer therapies (e.g., Rife70 and Naessens71) believed these hard to detect organisms caused types of cancers, and as I showed here, they are also linked to many autoimmune conditions.72
A 1967 Russian study tested cancer patients for pleomorphic bacteria, isolating them from blood samples of patients and those around people who had died from cancer.73 They took 59 samples from 53 patients and 17 tumor samples, with most yielding pleomorphic bacteria, which due to their small size, were highly susceptible to DMSO.
Given that these microorganisms may induce cancerous changes, DMSO’s ability to eliminate them could also potentially explain its differentiating properties. Likewise, its ability to eliminate them74 may explain why DMSO effectively treats so many autoimmune disorders (as pleomorphic bacteria has been repeatedly detected in the reactive tissues).
Cancer Growth Inhibition
When DMSO differentiated cancer cells, it also frequently slowed their growth in cultures or implanted animals in a dose dependent fashion75,76 (which was often permanent at higher concentrations that were far below the toxic dose to normal cells77). For example, consider this 2014 study, where breast cancer cells were implanted into mice who were then injected with DMSO or saline:78
In turn, this phenomenon has been observed in various cancers, including AML,79 breast cancer80 (doing so more effectively than thalidomide), lymphomas,81 colon cancer,82 erythroleukemia,83 intestinal cancer,84 liver,85 lung cancer,86 melanoma,87 nasopharyngeal,88 rectal cancer,89 ovarian cancer,90 prostate cancer,91 sarcomas.92
Note: Very low concentrations of DMSO can affect cancer cells (e.g., a 2021 study found 0.0008% DMSO had significant effects on the biochemical activity of cancer cells93).
Additionally, when DMSO differentiates cancer cells, it can also induce programmed cell death (apoptosis) in them (e.g., in AML,94 and lymphomas95,96,97).
Immune Activation
While DMSO is highly effective at reducing autoimmunity and inflammation within the body, it does not impair the immune system’s response to cancer, and if anything enhances it.
A key reason for this is that DMSO achieves what many conventional immunotherapies aim to do — prevent cancer from evading the immune system, thereby allowing the cancer to be targeted and eliminated.
This was first shown by a renowned cancer researcher, who found DMSO caused the immune system to eliminate large rectal HPV warts that were otherwise quite challenging to treat (e.g., in a 1978 JAMA paper he reported successfully treating 22 of 23 patients98).
Note: Topical DMSO can be effective for a variety of skin lesions, including warts and cancer.
Much later, a pivotal 2016 study proved it was possible to use DMSO to make a simple “vaccine against cancer.”99 It exposed liver cancer cells to 2% DMSO, which temporarily slowed their growth and permanently changed their gene expression.
These treated cells were then injected into mice and, unlike untreated cancer cells, did not form tumors. Crucially, the DMSO-treated cells induced an antitumor immunity that allowed the mice to completely eliminate untreated liver cancer cells.
This treatment also conferred a partial immunity to the mice against certain other cancers, specifically B16-F10 melanoma cells. The study found that DMSO treatment increased the activation of cancer-eliminating immune cells (CD4+, CD8+ T cells, and NK cells). Mice lacking a functional immune system did not respond to this therapy, confirming the importance of the immune response.
DMSO’s ability to increase immune recognition of cancers may be due to its changing the exposed antigens or receptors on the cell membrane surface.100 For example:
• DMSO increased the surface expression of lung cancer H-2K and H-2D antigens at least 100-fold101 (hence making DMSO aid the immune system in being able to target the cancer102,103,104). In a follow-up study, the authors showed this H-2 change greatly increased their susceptibility to being eliminated by the immune system (via H-2-restricted immune lysis).105 Likewise, DMSO induced surface antigen expression in melanoma106 and T-cell lymphoma.107
• DMSO increased the ability of the spleen (likely its macrophages) to identify and eliminate cancerous cells,108 and increased the presence of antitumor macrophages while decreasing pro-tumor macrophages.109
Note: Leukemic cells DMSO differentiates into immune cells have an increased ability to mount an immune response to cancers.110,111,112
Cancer Treatment Studies
These cancer fighting properties have also been demonstrated in living organisms. For example:
• A 1967 study induced breast cancers in mice and found that drinking DMSO caused a small reduction in their rate of occurrence and prevented some of weight loss caused by the cancers.113
• A 1989 study of rats with aggressive (implanted) prostate cancers found that 2.5% oral DMSO significantly slowed the cancer’s growth.114
•A 2008 MRI study evaluated the microvasculature of mice with implanted tumors before and after a week course of DMSO.115 It found DMSO greatly reduced cancer vascular permeability, which is potentially significant for cancer management as leaky blood vessels can support rapid irregular growth or metastasis and can compress surrounding tissues or cause inflammation and sometimes interfere with the delivery of chemotherapy to those cells.
Note: Many holistic schools of medicine have concluded cancers arise from poor blood flow to a tissue or poor lymphatic drainage from it. Given DMSO’s remarkable ability to improve circulation, it is highly possible that this contributes to its ability to prevent cancer.116
• A 2011 study found that in mice with experimentally induced Dalton’s lymphoma, injected DMSO was shown to regress their tumors and upregulate TNFα and p53 in lymphoma cells, which impaired their metabolic pathways and triggered an apoptotic pathway (whereas normal white blood cells were unaffected).117
Likewise in humans:
• A 1992 study118 conducted by an Iraqi researcher (who’d found DMSO cured a variety of challenging gastrointestinal conditions119) conducted a controlled trial of 198 patients who’d had surgery for colon cancer (in the sigmoid) that had spread into the local lymph nodes, and found that the long term administration of oral DMSO after the electrosurgery significantly improved their 5 year survival.120
• That researcher also conducted a 1992 controlled trial of 228 patients who’d just had an uneventful surgery to remove two-thirds of their stomachs (due to stomach cancer).121 Daily oral DMSO significantly increased their survival rates in the 160 patients who could be evaluated at 5 years.
• A 1999 trial of 25 patients found intravesical DMSO treated bladder cancer.122
Additionally, one cancer (multiple myeloma) is characterized by the uncontrolled growth of malignant plasma cells in the bone marrow, which produce abnormal proteins (such as amyloids) that can overwhelm the body. While amyloidosis is challenging to treat, there are over 40 studies demonstrating that DMSO prevents amyloid proteins from clumping together and instead eliminates their deposits from the body (often leading to a clinical improvement123).
In turn, case reports have found DMSO effectively treated multiple myeloma amyloidosis in a variety of soft tissues and organs,124,125,126,127 and in one instance in combination with chemotherapy to treat the cancer as well.128
Conclusion
While history is full of effective medical therapies being largely erased from human memory, I have always found the DMSO story particularly unbelievable as there was so much published evidence it worked for a variety of challenging conditions and many (e.g., including respected congressmen, doctors and academics) fought for decades for the FDA to permit its use.
This erasure is particularly remarkable in the cancer field as there are hundreds of studies (including some very recent ones) showing DMSO can effectively achieve many of key goals in modern cancer treatment research.
Yet for some reason, DMSO exists in a bubble where it’s acknowledged it can create those anticancer effects as needed in cancer research, but it’s almost never then viewed as a cancer therapeutic. For example to quote a 2023 review paper on DMSO’s cancer treating properties:129
“Recently, DMSO has been included in biological cancer treatment and several FDA approved cancer immune therapeutic modalities such as CarT cell therapy130 and melanoma drug Mekinist (trametinib DMSO).131
However, besides its recognized biological role as a pharmaceutical solvent and cryoprotectant, there was no mention of DMSO’s possible ability to potentiate therapeutic activity as a component of these cancer treatments.”
Fortunately, because of its ease of availability (made possible by the 1994 DSHEA Act132) and frequency with which it produces rapid results, drawing attention to DMSO has allowed it to make a rapid resurgence, and I am hopeful we can make that eventually allow its benefits to be widely available to cancer patients — particularly since DMSO’s ability to potentiate natural and conventional cancer treatments completely transforms the treatment of cancer.
Author’s Note: This is an abridged version of a longer article that reviews the point mentioned here in more detail and reviews how DMSO reduces cancer pain, the complications of radiation therapy and chemotherapy and how it greatly enhances the effectiveness of both conventional and natural cancer therapies. That article (along with guidance for using DMSO) can be read here.
A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD’s exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD’s work, be sure to check out The Forgotten Side of Medicine on Substack.
How DMSO Eases Cancer’s Hidden Burdens — Chemo, Pain, and Radiation Relief
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/04/04/how-dmso-eases-cancers-hidden-burdens.aspx
Analysis by A Midwestern Doctor April 04, 2025
STORY AT-A-GLANCE
- Dimethyl sulfoxide (DMSO), a forgotten gem from the 1960s, effectively treats a broad spectrum of conditions, including strokes, tissue injuries, autoimmune inflammation, a myriad of skin diseases, and many challenging infections
- One of the least-known benefits of DMSO is that it also eliminates cancers (especially when combined with another therapy) and protects the body from damage created by conventional cancer therapies
- In dozens of experiments, DMSO has been shown to prevent the damage radiation does to cells, animals, and humans and to heal existing radiation injuries — something relevant not only to cancer patients but also to those receiving CT scans
- DMSO effectively prevents many of the illnesses and complications that follow chemotherapy. Likewise, it also protects patients from accidental chemotherapy injuries where the medication leaks into the tissue
- DMSO heals surgical wounds (which prevents many complications from cancer surgeries) and significantly extends the survival of patients whose tumors were surgically removed
DMSO is a remarkable naturally occurring substance that (provided it’s used correctly1) safely and rapidly improves a variety of conditions medicine struggles with — particularly chronic pain. For example, thousands of studies show DMSO treats a wide range of:
• Injuries such as sprains, concussions, burns, surgical incisions, and spinal cord injuries (discussed here).
• Strokes, paralysis, many neurological disorders (e.g., Down syndrome and dementia), and numerous circulatory disorders (e.g., Raynaud’s, varicose veins or hemorrhoids), which were discussed here.
• Chronic pain (e.g., from a bad disc, bursitis, arthritis, or complex regional pain syndrome), which was discussed here.
• Many autoimmune, protein, and contractile disorders such as scleroderma, amyloidosis, and interstitial cystitis (discussed here).
• Head conditions, such as tinnitus, vision loss, dental problems, and sinusitis (discussed here).
• Internal organ diseases such as pancreatitis, infertility, liver cirrhosis, and endometriosis (discussed here).
• A wide range of skin conditions such as burns, varicose veins, acne, hair loss, ulcers, skin cancer, and many autoimmune dermatologic diseases (discussed here).
Many challenging infections such as shingles, herpes, chronic ear or dental infections, and osteomyelitis (discussed here). In turn, since I started this series, it struck a cord, and I have received over 2000 reports of remarkable responses to DMSO, and many readers have had for a variety of “incurable conditions.”
This begs an obvious question — if a substance capable of doing all of that exists, why does almost no one know about it? Simply put, like many other promising therapies, it fell victim to a pernicious campaign by the FDA, which kept it away from America despite decades of scientific research, congressional protest, and thousands of people pleading for the FDA to reconsider its actions. Consider for example, this 60 minutes program about DMSO that aired on March 23, 1980:
DMSO and Cancer
Since there is a longstanding tendency for any “unproven cancer therapy” to be targeted by the medical industry, once the pioneers of DMSO realized early research showed DMSO was also remarkable for cancer, a decision was made not to focus on that research as a justifiable fear existed that doing so would bury DMSO (particularly since DMSO was already in a precarious position with the FDA). As a result, there is very little knowledge of how DMSO changes the cancer paradigm. For example:
• There are hundreds of studies showing DMSO routinely transforms cancerous cells into noncancerous ones.
• DMSO directly inhibits the growth of a wide range of cancers.
• DMSO allows the immune system to regain the ability to target cancerous cells that have evaded the immune system,2 which not only eliminates cancer but also can create permanent immunity to cancers.
• DMSO makes many conventional cancer therapies much more potent, both making a cure more likely and a far lower (and thus less toxic dose) dose needed to achieve it.
• Many natural therapies become dramatically more potent when combined with DMSO (e.g., one DMSO combination ranks amongst the most effective cancer treatments I’ve ever encountered).
Furthermore, in addition to directly eliminating cancers, DMSO’s remarkable ability to heal and protect the body can also make challenging cancers far more manageable. In my eyes, the suppression of DMSO’s uses as an adjunctive cancer therapy represents the most egregious aspect of this story as in those instances, it’s not even competing with cancer treatments — it’s just reducing the suffering they cause (which if anything should be good for the cancer business).
DMSO and Radiation Therapy
Many of DMSO’s remarkable properties result from it effectively protecting cells from a variety of otherwise lethal stressors (e.g., burns,3 freezing,4 blood loss,5 asphyxiation,6 UV light,7 and soundwaves8) and it significantly accelerates healing from injuries (e.g., sprains9 or burns10).
In addition to protecting cells from other sources of injury, as early as 1961,11 DMSO was also recognized to protect cells and tissues from radiation exposure, and by 1967,12 to protect the skin. This is because DMSO prevents radiation from:
• Breaking apart chromosomes,13 DNA, RNA, proteins,14 and the mitochondria.15
• Creating damaging oxygen species16 and free radicals.17
• Triggering an immune response (e.g., by reducing IL-1, IL-6, TNF-α, and TGF-β18), chronic inflammation, fibrosis, and adhesions.
• Putting cells into senescence19 (a state of permanent growth arrest).
• Causing normal cells in the vicinity of the affected ones to die as well (e.g., when only 1% of cells are exposed to radiation, approximately 30% of non-irradiated cells will exhibit similar toxic effects too20), a fascinating phenomenon I believe is mediated through mitogenic radiation emissions.
Since cancer radiation therapy frequently creates a variety of acute and chronic injuries such as burns, fibrosis, and internal tissue adhesions (all of which DMSO treats), DMSO is incredibly valuable for cancer patients undergoing radiation therapy — particularly since DMSO not only prevents radiation damage but also rapidly heals the injuries radiation creates.21,22
Most importantly, DMSO’s protective effects are specific to normal cells. In contrast, many studies show it increases cancer cells’ susceptibility to radiation.23
Note: I believe our focus on radiation therapy ultimately resulted from mining magnate James Douglas devising a way to produce cheap radium and then giving a large donation (along with subsequent donations) to America’s premier cancer institute to create a program for developing cancer radiation therapy that then spread across the world.24,25
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Radiation Exposure Studies
Studies have repeatedly shown that DMSO protects cells26 (particularly when given prophylactically27) from being damaged by (often otherwise fatal28) radiation. For example, DMSO was shown to protect skin cells from dying after exposure to gamma radiation29 and make hamster cells four times as resistant to radiation.30
These same protective properties have also been found in plants31,32,33 and many animals (e.g., mice,34,35,36,37,38,39,40,41,42,43 rats,44,45,46,47,48,49 rabbits,50 newts,51 and fruit flies52).
In animals, DMSO was repeatedly found to protect them from otherwise lethal radiation exposures53,54,55 and protect their skin,56 tails,57 oral mucosa,58 eyes,59 kidneys,60 intestines61 (which are particularly vulnerable to radiation damage), and testicles62 from radiation damage, along with protecting sperm from mutations63 and to accelerate tissue cellular regeneration following an injury.64
Finally, DMSO was shown to prevent the psychological trauma and behavioral changes rats typically experienced from radiation injuries (presumably by preventing radiation from causing injury65).
DMSO also has a remarkable ability to protect and heal the skin from injury,66 and since 1966,67 numerous Russian, German, and Japanese studies have demonstrated DMSO’s impressive ability to protect human skin (along with its collagen and mucopolysaccharides) from radiation.68,69,70,71,72,73,74,75,76,77,78,79,80
For example, DMSO has been shown to treat radiation fibrosis,81,82 radiation dermatitis,83 radiation injuries84 and other local radiation complications.85
Note: While DMSO can treat radiation injuries, it is the most effective if given immediately beforehand to prevent radiation injuries.86
DMSO has also been shown to protect tissues besides the skin. For example:
• In 80 patients who’d developed late local radiation complications (induration, ulcers) from the treatment of breast or genital cancer (or a non-cancerous disease) DMSO resulted in both a high efficacy of treatment with no side effects.87
• In 22 patients with cervical cancer topical found DMSO prior to internal gamma-ray radiation therapy prevented the normally expected radiation burns and other toxic reactions to the treatment (e.g., in the bladder and rectum) seen in 59 controls and that DMSO did not protect cancerous tissue.88
• In 807 patients with cervical uterine cancer, putting 10% DMSO into the bladders an hour before receiving weekly internal irradiation therapy, dropped the radiation damage to the rectum from 19.0% to 9.5% and to the bladder from 8.8% to 7.1% (both of which dropped to 1.7% if metronidazole was also used).89
• In another study, DMSO had a 50% success rate in treating patients which chronic radiation cystitis (e.g., from prostate cancer therapy).90 Likewise, a 1979 study also used DMSO to treat radiation cystitis.91
• In 22 breast and cervical cancer patients, DMSO protected them against radiation dermatitis (e.g., erosion, blistering, itching, and pain) while also enhancing cancer sensitivity to radiation (as the DMSO treated areas showed skin reddening and exfoliation earlier) and accelerating the regrowth of normal tissues.
Additionally, when DMSO was only applied to one side, the non-applied side did worse, the hyperpigmentation that follows radiation therapy was greater in DMSO treated patients, and that only one of the 22 patients had to stop DMSO (due to having a skin eruption which may have been linked to DMSO).92
• This author detailed a case of a patient with lung cancer that was treated with three months of radiation therapy but severely damaged her lungs (making her require oxygen and leaving her unsure if she’d survive) — but after topical and oral DMSO, she had a rapid recovery.
Likewise, he also shared a case of another woman with lung cancer who was expected to have significant lung complications from the treatment (as she required a borderline lethal dose), but took topical DMSO prior to each treatment and instead had no complications and was fully healthy three years later.93
It is thus quite remarkable that all of this remains unknown. To quote the author of a 2022 study94 which found DMSO prevented testicular damage (and loss of hormonal function or fertility) following radiation therapy:
“Currently, there is no approved agent for the prevention or treatment of radiation-induced testicular injury … In summary, our findings demonstrate the radioprotective efficacy of DMSO on the male reproductive system, which warrants further studies for future application in the preservation of male fertility during conventional radiotherapy and nuclear accidents.”
Similarly, in addition to the higher doses experienced from radiation therapy, diagnostic radiation, specifically CT scans (which expose the body to much higher radiation doses than X-rays) also pose a cancer risk — particularly since the dose of radiation with CT scans can have over a 10-fold variation.95
In turn, a CT scan was found to make you 17% to 24% more likely to develop cancer,96 with the risk increasing97 the younger you were at the time of the scan and is much higher for certain types of cancers.98,99,100,101,102 A 2009 study estimated 29,000 cancers were caused by the CT scans performed in America in 2007.103
As such, I avoid CT scans, which I do not feel are essential (particularly since a detailed physical exam frequently provides more actionable information). It is my sincere hope at some point in the future, DMSO will be given in conjunction with CT scans (but unfortunately their use keeps going up, and they are viewed as a highly lucrative growth market104).
Tumor Surgery
Since DMSO rapidly accelerates the healing of tissue and addresses the neurological components of pain, many studies have found that DMSO greatly facilitates surgical recovery (e.g., by accelerating healing, improving the strength of the final scar, reducing surgical site pain and eliminating fibrosis, enlarged scars, or tissue adhesions).
As cancers are frequently treated with surgical removal, DMSO can also greatly aid the recovery from these surgeries (e.g., in dogs that required a unilateral mastectomy, giving IV DMSO 15 minutes before the surgery’s conclusion significantly reduced post-surgical inflammation105).
Likewise, studies such as a 1992 trial106 of 198 patients with Stage III colon cancer, and a 1992 trial107 of 228 patients with stomach cancer found DMSO significantly reduced the chance that those cancers would relapse.
Extravasation Injuries
Since the medical field has been extremely reluctant to consider any alternative cancer treatment that could threaten its bottom line (regardless of how much data is behind it), DMSO has essentially not been utilized in the treatment of cancer. However, there is one exception to this rule, as DMSO is able to address a challenging issue encountered with chemotherapy without threatening the existing market.
Since many chemotherapy drugs are quite toxic, they have to be administered in a tightly controlled manner. Unfortunately, in many cases however, the drug gets through the injected vein (extravasates) and leaks into the surrounding tissue.
Note: Since extravasations are often not reported, estimates widely vary on how common they are (e.g., according to one study, in 0.1% to 6% of adults who receive chemotherapy108 while another made a compelling case extravasations occur in 39% of patients109).
Due to how toxic some of the chemotherapy drugs are (particularly the anthracyclines), when that leakage occurs and the drugs concentrate in one area, it can often cause significant damage to the surrounding tissues and lead to ulceration or necrosis (tissue death).
Since the existing treatments don’t always give satisfactory results and DMSO is extremely effective at healing a wide range of tissue injuries, it eventually got used as a treatment for these injuries and quickly caught on. For example:
• A 1981 rat study of doxorubicin extravasations showed that daily topical applications of 1 ml 90% DMSO with 10% α-tocopherol significantly reduced ulcer diameter.110
• A 1982111 and 1986112 study tested numerous agents on ulcers created by applying intradermal doxorubicin to pigs and rats and found DMSO was the only agent that prevented or healed those ulcers.
• A 1984,113 1987,114 and 1994115 pig study along with a 2007 rat study116 also found DMSO treated or prevented extravasation injuries.
Likewise, in humans:
• A 1983117 case report, another 1983 case report,118 a 1989 series119 of 4 patients, a 1991 series120 of two patients, a 1994 series of two patients121 and a 2001 case report122 reported that DMSO prevented extravasations from causing ulcerations of tissue death or healed existing injuries (e.g., with “striking” improvement).
• A 1988 study gave topical DMSO for anthracycline extravasations every 6 hours for 14 days to 20 patients, which prevented all of them from developing ulcerations. In the 14 who were evaluated at 3 months, there was no sign of residual damage in six patients, while a pigmented indurated area remained in ten.123
• A 1995 study gave topical DMSO (for 8 hours a day over 7 days) alongside 3 days of intermittent cooling to every patient who experienced an extravasation over a 3.5 year period (which was either from doxorubicin, epirubicin, mitomycin, mitoxantrone, cisplatin, carboplatin, ifosfamide or fluorouracil).
Of those 144 patients, 127 could be evaluated, of whom only 1 ultimately developed an ulceration from the extravasation, and none experienced side effects from DMSO (beyond temporary skin irritation and a breath odor).124
• A 1996 study of ten successive patients who experienced extravasation from chemotherapy were given DMSO and alpha-tocopherol, all of whom avoided ulceration or tissue death.125
• A 2004 study of 147 patients with extravasations of anthracyclines (which typically leads to 28% developing ulcerations), found 99% DMSO caused only 1% to 2% of them to develop ulcers.126
• A 2007 study explored applying DMSO and α-tocopherol as a gel rather than a liquid solution to treat extravasation injuries (which appeared to hold promise).127
Chemotherapy Injuries
In addition to addressing extravasation injuries, DMSO has also:
• Been found to prevent doxorubicin cardiac toxicity.128
• Successfully treated palmar-plantar erythrodysesthesia resulting from doxorubicin treatment.129
• Prevent the skin death that is often associated with injecting doxorubicin into the eyelid (which is done to treat eye spasms).130
• Protect against birth defects caused by hydroxyurea.131
• Reduce the carcinogenicity of chlorambucil (which often causes a secondary tumor to form after the initial treatment).132
• Potentially decrease the lung injuries (e.g., pulmonary fibrosis) and weight loss caused by bleomycin.133,134,135
DMSO has also been found to improve many other symptoms associated with chemotherapy (e.g., DMSO is frequently used to treat hair loss from a variety of causes, including chemotherapy) since it saves normal cells on the verge of dying following chemotherapy.
Note: We find Ultraviolet Blood Irradiation following chemotherapy to be the most effective option for protecting a patient’s healthy cells from dying.
Cancer Pain
Cancer (and its treatments) are often accompanied by many other debilitating symptoms, including pain — which is so severe that opioids, rather than being restricted, are routinely used to treat it (e.g., fentanyl is often used to treat advanced cancer pain — but in 10% to 20% of patients the pain is severe enough that even the strongest opioids can’t address it136).
Since DMSO has a rather unique mechanism of treating pain, it is often able to treat a wide range of challenging pain conditions nothing else works on (e.g., I’ve now had hundreds of readers share life-changing pain improvements from topical DMSO nothing else they’d tried had ever worked on). As such, many over the years have found it provided incredible relief for metastatic cancer pain.
One of the most well-known examples was Otis Bowen MD (a popular second-term Indiana governor), who “illegally” used topical DMSO to treat his wife’s pain from terminal multiple myeloma and then publicly denounced the FDA’s absurd embargo on it at the AMA’s 1981 national meeting.137
Remarkably, a few years later, Bowen became Reagan’s Secretary of Health and Human Services. Still, even then, with this highly ethical doctor at the helm of the HSS, DMSO was unable to overcome the FDA’s prohibition of it — which helps to highlight the incredible challenge RFK Jr. is now facing (but gradually surmounting). Likewise, a few studies have shown that DMSO can treat cancer pain:
• A 1967 study included two older patients with cancer pain, one of whom had an excellent response to DMSO and one who had a good response.138
• A 1967 study found that of 7 patients with metastatic cancer pain, DMSO gave 2 full and 2 partial remission.139
• A 2011 trial gave DMSO and sodium bicarbonate to 26 patients with advanced cancers who were experiencing significant pain (even with all the available treatment options).140 This greatly improved their pain, their quality of life (e.g., chemotherapy symptoms), their blood counts, and their organ function:
Note: A 2010 paper further discusses DMSO’s ability to treat intractable cancer pain.141 It highlights that this may be due to DMSO’s ability to address membrane hyper-excitability (e.g., through suppressing NMDA and AMPA induced ion fluxes — which are linked to central pain sensitization142,143 and may explain why DMSO also effectively treats complex regional pain syndrome144).
Conclusion
DMSO’s ability to heal the body and restore its normal function transformed the practice of medicine, and had the FDA not buried DMSO sixty years ago; our medical science would be leaps beyond where it is now. In this article, I’ve tried to show how DMSO helps to address one of the most challenging decisions many will face in their lifetimes — is it worth tolerating the immense damage conventional cancer therapies will cause in return for them potentially saving one’s life?
As such, it’s unconscionable that DMSO was never incorporated as an adjunctive therapy for conventional cancer care, particularly in the case of radiation therapy, since a vast body of literature shows simply applying it shortly beforehand can prevent most of the complications from radiation therapy and significantly increase its ability to treat cancer.
However, while it has been immensely painful to watch the unnecessary suffering created by our outdated and pathological medical practices, for the first time in my life, I am simultaneously immensely hopeful. That is because Make America Healthy Again has created the window to spark the momentum to begin revisiting many of our long accepted medical practices and have our society ask if there is actually a better (or more affordable) way to do things.
Author’s Note: This is an abridged version of a longer article that reviews how DMSO also directly treats cancer (e.g., by turning cancer cells back into normal cells or mobilizing the immune system to eliminate them) and how it greatly enhances the effectiveness of both conventional and natural cancer therapies (along with guidance for using DMSO to treat cancer and many other related conditions). That article can be read here.
A Note from Dr. Mercola About the Author
A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD’s exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD’s work, be sure to check out The Forgotten Side of Medicine on Substack.
1. The Forgotten Side of Medicine, September 29, 2024
2. The Forgotten Side of Medicine, March 15, 2025
3. The Forgotten Side of Medicine, September 15, 2024
4. The Forgotten Side of Medicine, September 15, 2024
5. The Forgotten Side of Medicine, September 15, 2024
6. The Forgotten Side of Medicine, September 15, 2024
7. Radiatsionnaia Biologiia, Radioecologiia, 01 Mar 2014, 54(2):169-173
8. Ann N Y Acad Sci. 1975 Jan 27:243:358-61
9. The Forgotten Side of Medicine, September 29, 2024
10. The Forgotten Side of Medicine, December 1, 2024
11. Int J Radiat Biol Relat Stud Phys Chem Med. 1961 Jan:3:41-8
12. Annals of the New York Academy of Sciences, 141(1), Pages 45-62
13. Cytogenet Genome Res. 2004;104(1-4):168-72
14. Curr. Issues Mol. Biol. 2024, 46(11), 12718-12732
15. Curr. Issues Mol. Biol. 2024, 46(11), 12718-12732
16. Curr. Issues Mol. Biol. 2024, 46(11), 12718-12732
17. The Forgotten Side of Medicine, March 15, 2025
18. Radiat Oncol J. 2014 Sep 30;32(3):103–115
19. Semin Radiat Oncol. 2017 Oct;27(4):316–324
20. Journal of Radiation Research, Volume 64, Issue 6, November 2023, Pages 870–879
21. The Forgotten Side of Medicine, September 29, 2024
22. The Forgotten Side of Medicine, December 1, 2024
23. The Forgotten Side of Medicine, March 15, 2025
24. Wikipedia, James Walter Douglas
25. National Academy of Sciences, 1951
26. The Forgotten Side of Medicine, March 15, 2025
27. Radiat Environ Biophys. 1985;24(3):175-84
28. Radiat Environ Biophys. 1985;24(3):175-84
29. Department of Dental Radiology, Kyungpook National University, 2002
30. Radiat Res. 1981 Apr;86(1):52-66
31. Radiation Botany, Volume 9, Issue 2, 1969, Pages 111-114
32. Radiation Botany, Volume 10, Issue 1, 1970, Pages 69-78
33. University of Nottingham, (2021)
34. Annals of the New York Academy of Sciences, 141(1), Pages 63-64
35. Health Physics 13(6):p 601-606, June 1967
36. Int J Radiat Biol Relat Stud Phys Chem Med. 1970;18(4):301-9
37. Radiat Res. 1970 Nov;44(2):368-78
38. International Journal of Radiation Oncology*Biology*Physics, Volume 102, Issue 5, 1 December
2018, Pages 1577-1589
39. Radiat Res (1996) 145 (6): 740–745
40. Oxidative Medicine and Cellular Longevity, 2022(1), 9137812
41. Clin Orthop Relat Res. 2021 Mar 1;479(3):468-474
42. Experientia. 1967 Nov 15;23(11):923
43. J Invest Dermatol. 1969 Mar;52(3):277-9
44. Ann N Y Acad Sci. 1967 Mar 15;141(1):45-62
45. Br J Radiol. 1968 Dec;41(492):950
46. Journal of BUON 17: 160-167, 2012
47. Br J Radiol. 1968 Dec;41(492):950
48. Radiobiology (USSR), 01 January 1977
49. Pharmacologica, 01 February 1970, Volume 26, Pages 164–165, (1970)
50. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, 9(3), 266-272
51. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and
Medicine, 18(3), Pages 217–233
52. Radiat Res. 1972 Jul;51(1):134-41
53. Annals of the New York Academy of Sciences, 141(1), Pages 63-64
54. Ann N Y Acad Sci. 1967 Mar 15;141(1):45-62
55. Radiat Res. 1972 Jul;51(1):134-41
56. Br J Radiol. 1968 Dec;41(492):950
57. Radiation Botany, Volume 10, Issue 1, 1970, Pages 69-78
58. International Journal of Radiation Oncology*Biology*Physics, Volume 102, Issue 5, 1 December
2018, Pages 1577-1589
59. Radiat Res. 1970 Nov;44(2):368-78
60. Journal of BUON 17: 160-167, 2012
61. Radiat Res (1996) 145 (6): 740–745
62. Oxidative Medicine and Cellular Longevity, 2022(1), 9137812
63. Radiat Res. 1972 Jul;51(1):134-41
64. Radiobiology (USSR), 01 January 1977
65. Experientia 26, Pages 164–165 (1970)
66. The Forgotten Side of Medicine, December 1, 2024
67. Klinische Wochenschrift, 01 Oct 1966, 44(19):1151-1152
68. Klinische Wochenschrift, 01 Oct 1966, 44(19):1151-1152
69. Ger. Med. Mon., 12: 443-4(Sept. 1967)
70. J. Invest. Dermatol., 52: 277-9(Mar. 1969)
71. Med Radiol (Mosk). 1974 Nov;19(11):66-8
72. Med. Radiol.; (USSR); Journal Volume: 23:6
73. Ger. Med. Mon., 12: 443-4(Sept. 1967)
74. J. Invest. Dermatol., 52: 277-9(Mar. 1969)
75. Med. Radiol.; (USSR); Journal Volume: 23:6
76. Med Radiol (Mosk). 1974 Nov;19(11):66-8
77. Klinische Wochenschrift, 01 Oct 1966, 44(19):1151-1152
78. Radiobiol.-Radiother. 11: No. 4, 399-404(1970)
79. Radiobiologia, Radiotherapia, 01 Jan 1973, 14(5):471-479
80. IAEA, Published 1988 | Version v1
81. Zentralblatt fur Gynakologie, 01 Jul 1972, 94(27):854-858
82. Radiobiol.-Radiother. 11: No. 4, 399-404(1970)
83. Nippon Igaku Hoshasen Gakkai Zasshi, 26: 210-14(May 1966)
84. IAEA, Published 1988 | Version v1
85. Med Radiol (Mosk). 1977 May;22(5):17-23
86. Med. Radiol.; (USSR); Journal Volume: 23:6
87. eLIBRARY, 1977 (Archived)
88. Med Radiol (Mosk). 1985 Mar;30(3):16-8
89. Vestn Rentgenol Radiol. 2006 May-Jun:(3):47-51
90. Urology. 1978 Mar;11(3):215-20
91. IAEA, Published 1979 | Version v1
92. The Forgotten Side of Medicine, March 15, 2025
93. Amazon, The DMSO Handbook for Doctors
94. Oxidative Medicine and Cellular Longevity, 2022(1), 9137812
95. FDA, December 5, 2017
96. BMJ 2013;346:f2360
97. DailyMail.co.uk, March 10, 2025
98. DailyMail.co.uk, March 10, 2025
99. BMJ 2013;346:f2360
100. BMC Cancer. 2022 Nov 30;22:1238
101. Arch Intern Med. 2009;169(22):2071-2077
102. JNCI Cancer Spectr. 2019 Nov 14;4(1):pkz072
103. Arch Intern Med. 2009;169(22):2071-2077
104. Collective Minds, November 2, 2024
105. cabidigitallibrary.org, (2020): 20203508209
106. Chemotherapy. 1992;38(2):127-34
107. Chemotherapy. 1992;38(2):135-44
108. ISRN Dermatol. 2013 May 8;2013:856541
109. ISRN Dermatol. 2013 May 8;2013:856541
110. Cancer Res (1981) 41 (9_Part_1): 3395–3399
111. Cancer Treat Rep. 1982 Jun;66(6):1371-4
112. Journal of Clinical Oncology, Volume 4, Number 9, September 1, 1986
113. Diss. Catholic University of America, 1984
114. Oncol Nurs Forum. 1987 Jan-Feb;14(1):39-44
115. Annals of Surgical Oncology 1, Pages 411–414 (1994)
116. Journal of Southern Medical University, 01 Sep 2007, 27(9):1444-1446
117. Annals of Internal Medicine, Volume 98, Number 6, 1 June 1983
118. Cancer Treat Rep. 1983 Apr;67(4):407-8
119. Cancer Chemother. Pharmacol. 23, 316–318 (1989)
120. Oncol Nurs Forum. 1991 May-Jun;18(4):693-5
121. Journal of Intravenous Nursing 17(5):p 261-266, September 1994
122. Acta Oncologica, 40:4, 541-542
123. J Clin Oncol. 1988 Nov;6(11):1732-5
124. J Clin Oncol. 1995 Nov;13(11):2851-5
125. Annales de Dermatologie et de Venereologie, 01 Jan 1996, 123(10):640-643
126. Journal of Oncology Pharmacy Practice, December 2004
127. Arch Dermatol Res 299, 201–207 (2007)
128. Clinical Research 1983 Jan 1 (Vol. 31, No. 2, pp. A406-A406)
129. Cancer Chemother Pharmacol 44, 303–306 (1999)
130. kiss.kstudy.com, March 2002
131. Toxicology Letters, Volume 211, Supplement, 17 June 2012, Page S183
132. Medical Hypotheses, Volume 6, Issue 10, October 1980, Pages 1035-1041
133. Biochemical Pharmacology, Volume 34, Issue 13, 1 July 1985, Pages 2386-2389
134. Toxicology. 1989 Feb;54(2):197-205
135. Seoul University Journal of Veterinary Science, 1994-08-15, Volume 12 Issue 2
136. Pain Ther. 2023 Apr 13;12(3):645–654
137. NYtimes.com, November 8, 1985
138. Ann N Y Acad Sci. 1967 Mar 15;141(1):572-85
139. Annals of the New York Academy of Sciences, 141(1), 506-516
140. J Pain Palliat Care Pharmacother. 2011;25(1):19-24
141. Inflammation & Allergy-Drug Targets, Volume 9, Issue 4, Sep 2010, Pages 306-312
142. Exp Neurol. 2001 Jul;170(1):180-5
143. Anesth Analg. 2003 Oct;97(4):1108-1116
144. The Forgotten Side of Medicine, September 29, 2024