Glyphosate
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US Autism Rate Is Now 1 in 44
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2021/12/23/autism-rate-1-in-44.aspx
The original Mercola article may not remain on the original site, but I will endeavor to keep it on this site as long as I deem it to be appropriate, and will not be bullied into removing it.
Analysis by Dr. Joseph Mercola Fact Checked December 23, 2021

STORY AT-A-GLANCE
- In the mid-1960s, the autism rate was 1 in 10,000. By 2012, it had shot up to 1 in 88. In 2016, it was 1 in 68, and now it’s 1 in 44 8-year-olds
- Rates vary widely from state to state. In California, where incidence is the highest, 1 in 26 8-year-olds has a diagnosis of autism. Missouri, which has the lowest incidence, has a rate of 1 in 60
- Improved diagnosis alone cannot explain this trend. Genetics play only a minor role, and even then, primarily only when combined with toxic exposures
- Glyphosate appears to be a leading contributor to autism
- Other contributing factors include maternal antibodies associated with autoimmune diseases, maternal immune system overactivation and mitochondrial dysfunction (typically involving electron transport chain overactivity). Mitochondrial abnormalities are suspected of being involved in as many as 80% of cases
In the mid-1960s, the autism rate was 1 in 10,000.1 By 2012, it had risen to 1 in 88,2 then 1 in 68 as of 2016,3 and now, we’re looking at an autism rate of 1 in 44 8-year-olds, although rates vary widely from state to state.4
In California, where incidence is the highest, 1 in 26 8-year-olds has a diagnosis of autism. Missouri, which has the lowest incidence, has a rate of 1 in 60. According to the U.S. Centers for Disease Control and Prevention, the dramatic uptick is in part due to improved and more comprehensive identification and diagnosis.
However, improved diagnosis alone cannot explain this trend. One in 44 children were not autistic in the 1980s, with or without diagnosis. No, something is going on. One or more environmental factors are clearly having a devastating impact on our children.
Mitochondrial Dysfunction in Autism
According to an October 2020 scientific review5 in the journal Seminars in Pediatric Neurology, “Several lines of evidence implicate mitochondria in the pathophysiology of autism spectrum disorder (ASD).” For years, autism was believed to be due to genetics, but empirical studies have proven genetic predispositions play a very small role.
The authors point to “novel abnormalities” in mitochondrial function that have been found in autistic children, and the fact that treatments targeting mitochondrial dysfunction, such as L-carnitine supplementation and a ketogenic diet, have been fruitful.
In 2007, approximately 4% of autistic children could be diagnosed with a definite mitochondrial disease. More recent investigations looking at mitochondrial biomarkers and electron transport chain activity suggest mitochondrial abnormalities may be involved in as many as 80% of cases. Biomarkers of mitochondrial dysfunction include elevated levels of:
| Lactate | Pyruvate |
| Alanine | Creatine kinase |
| Ubiquinone | Acyl-carnitines |
| Carnitine (low levels being an indication of dysfunction) |
As noted by the authors, this is “remarkably interesting” because mitochondria are “very vulnerable to environmental factors.” In other words, something in our environment is triggering mitochondrial dysfunction in an ever-growing percentage of children. The question is what?
Children whose autism is rooted in mitochondrial dysfunction will typically have a key set of symptoms that include:
- Fatigability
- Gastrointestinal disorders
- Seizures and/or epilepsy
- Motor delay and/or ataxia and/or muscle weakness
- Unusual neurodevelopmental regression, including multiple regressions or regression later than commonly associated with ASD
Mitochondrial Overactivity
While classic mitochondrial disease is defined, at least in part, by severe deficits in electron transport chain activity, in children with ASD, mitochondrial dysfunction tends to involve overactivity. According to the authors:6
“… we have shown that about one-third of LCLs [lymphoblastoid cell lines] derived from children with ASD repeatedly show elevated respiratoryiou rates, approximately 200% of controls, for respiratory parameters associated with adenosine triphosphate production.
We have also demonstrated the consequences of elevated respiratory rates; specifically, this subset of ASD LCLs are more sensitive to acute exposure to reactive oxygen species (ROS) such that respiratory rates drop precipitously with acute increases in ROS.
We hypothesized these changes represent an adaptive response to previous environmental exposures, a phenomenon known as mitoplasticity.
To support this hypothesis, we demonstrated that elevated respiratory rates can be induced in LCLs with prolonged exposure (96 hours) to mild ROS, a microenvironment that simulates the effect of environmental toxicants on mitochondria.
Additionally, we have demonstrated that this subset of LCLs respond differently to environmental agents associated with ASD, including trichloroacetaldehyde hydrate and ethylmercury, and enteric short chain fatty acids propionate and butyrate, as compared to ASD LCLs which do not demonstrate these high respiratory rates at baseline.”
Important Nutritional Supplements
Two helpful treatments have already been mentioned: L-carnitine supplementation and ketogenic diets. Studies evaluating ketogenic diets and ASD have found them to be well-tolerated by a majority of children.
A review of four studies found 18% of children saw significant improvement on a ketogenic diet, 40% reported moderate improvement and 32% had mild improvement. Only 8% experienced a worsening of their symptoms.7
In cases where the ASD is caused by mitochondrial dysfunction, however, supplementing specific cofactors become important. The good news is this kind of supplementation is very safe and well tolerated. There’s virtually no risk involved, in terms of adverse side effects. Among the most important nutritional cofactors are:8
| B vitamins, including niacin (B3), riboflavin (B2), biotin (B7), thiamine (B1), pyridoxine (B6), pantothenic acid (B5), methylcobalamin (B12), reduced folate (B9) | Coenzyme Q10 or the reduced form, ubiquinol |
| L-carnitine or acetyl-L-carnitine | Creatine monohydrate |
| Alpha-lipoic acid | Vitamin E |
| Vitamin C | N-acetyl-L-cysteine (NAC) |
| Zinc |
Benefits of L-Carnitine and CoQ10
Of these, L-carnitine has been most widely studied. As explained in this paper:9
“Two medium sized (n = 30, 30) double-blind placebo-controlled studies using L-carnitine treatment (50 mg/kg/d for 3 months and 100 mg/kg/d for 6 months) found that scores on the Childhood Autism Rating Scale (CARS) improved with L-carnitine as compared to placebo with one study finding that greater symptomatic improvement was correlated with a greater increase in blood carnitine levels.
A small (n = 10) 8-week open-label trial of L-carnitine used particularly high doses (up to 400 mg/kg/d in 3 divided doses, maximum of 6000 mg/d) …
Several parental rated measures showed improvements in behavior and hyperactivity before correction for multiple comparisons and improvements in language correlated with post-treatment blood carnitine levels. Children with ASD and genetic mutations in the carnitine pathway also appear to response to L-carnitine.”
CoQ10 has also been evaluated in clinical trials. In one, 50 mg of ubiquinol was given twice a day for three months. Children who attained a CoQ10 blood level above 2.5 umol/L saw improvements in communication, interactions, sleep and food rejection.10
A three-month-long regimen of L-carnitine, CoQ10 and alpha-lipoic acid also produced encouraging results, improving mitochondrial function and ASD-related behavior. When the children discontinued the cocktail, their behavior worsened again.
Autism and Autoimmunity
Previous research also suggests ASD may have an autoimmunity component. As explained in a 2009 paper titled “Autoimmunity in Autism”:11
“Increasing evidence of autoimmune phenomena in individuals with autism could represent the presence of altered or inappropriate immune responses in this disorder, and this immune system dysfunction may represent novel targets for treatment.
Furthermore, in recent studies, antibodies directed against the fetal brain have been detected in some mothers of children with autism; these antibodies have the ability to alter behavioral outcomes in the offspring of animal models.”
Research12,13 published in 2013 found that more than 1 in 10 mothers of autistic children had antibodies associated with autoimmunity that adversely reacted with proteins in the brain of the baby, resulting in ASD. The authors point out that any activation of the mother’s immune system “might lead to an increased risk of a child with ASD.”
In light of the COVID injection campaign, the possibility of autoantibodies playing a role in ASD is extremely troublesome, as autoimmune diseases are a potential side effect. We don’t yet really know the extent of which the SARS-CoV-2 spike protein interacts with the human brain, but it’s clearly not beneficial.
Women, in particular, are suffering neurological dysfunction as a result of the COVID shot. How might the spike protein affect offspring? That’s still too early to say, but I suspect we’ll come to find that the effect can be devastating.
Toxic Chemicals Implicated in Autism
Not surprisingly, exposure to toxic chemicals in utero has also been identified as a potentially causative factor. According to the National Academy of Sciences, an estimated 3% of all neurobehavioral disorders in children are caused by toxic exposures.
Another 25%, the interaction of toxic exposures and genetic factors is thought to be causative.14,15 In 2012, scientists identified 10 chemicals suspected of causing learning disabilities and ASD:16
| Lead | Methylmercury |
| Polychlorinated biphenyls (PCBs) | Organophosphate pesticides, including glyphosate |
| Organochlorine pesticides | Endocrine-disrupting chemicals |
| Automotive exhaust | Polycyclic aromatic hydrocarbons (PAHs) |
| Brominated flame retardants | Perfluorinated compounds |
Of these, glyphosate is a top suspect17,18 for the simple reason that exposure to it is so widespread. Research19 published in 2019 found women exposed to 11 commonly used pesticides — including glyphosate — during pregnancy have a higher risk of having a child diagnosed with autism.
Pregnant women who lived within a 2,000-meter (1.24 miles) radius of a highly-sprayed area were 10% to 16% more likely to have children diagnosed with autism than those who lived farther away. As reported by Time:20
“When they looked at diagnoses of autism spectrum disorder that also came with intellectual disabilities, they found on average 30% higher rates among children who were exposed to the pesticides while in utero. Exposure in the first year of life increased the risk of autism by up to 50% compared to those not exposed to certain pesticides.”
Glyphosate Is Likely a Key Culprit
Stephanie Seneff, Ph.D., who has spent a large portion of her career studying glyphosate, believes it is a significant cause or contributor to autism. She’s shown glyphosate:
- Disrupts your gut microbiome
- Impairs peristalsis — a feature that is exceedingly common in children with autism21
- Inhibits bile acid release by impairing gallbladder contraction — Many autistic children have very pale stool, suggestive of low bile acid levels
- Impairs digestive enzymes — Many autistic children also have undigested particles in their stool, which suggests a lack of digestive enzymes. And, indeed, glyphosate affects your digestive enzymes, particularly trypsin, pepsin and lipase
The Roles of GI Inflammation and Maternal Gut Bacteria
Another potential trigger is maternal gut inflammation. Research22 published in early December 2021 found that when pregnant mice were challenged with immune activation, it changed their gut microbiota. This altered microbiota in turn primed the offspring for intestinal inflammation that resulted in neurodevelopmental disorders. MIT News reported the findings, noting:23
“Infection during pregnancy with elevated levels of the cytokine IL-17a may yield microbiome alterations that prime offspring for aberrant immune responses …
When a mother experiences an infection during pregnancy and her immune system produces elevated levels of the molecule Interleukin-17a (IL-17a), this can not only alter brain development in her fetus, but also alter her microbiome such that after birth the newborn’s immune system can become primed for future inflammatory attacks.
In four studies beginning in 2016,24 study co-senior authors Gloria Choi of MIT and Jun Huhof Harvard University traced how elevated IL-17a during pregnancy acts on neural receptors in a specific region of the fetal brain to alter circuit development, leading to autism-like behavioral symptoms in mouse models.
Their new research … shows how IL-17a can act to also alter the trajectory of immune system development. ‘We’ve shown that IL-17a acting on the fetal brain can induce autism-like behavioral phenotypes such as social deficits,’ says Choi …
‘Now we are showing that the same IL-17a in mothers, through changes in the microbiome community, produces co-morbid symptoms such as a primed immune system.’
The researchers caution that the study findings are yet to be confirmed in humans, but that they do offer a hint that central nervous and immune system problems in individuals with autism-spectrum disorders share an environmental driver: maternal infection during pregnancy.”
Here, the COVID-19 pandemic may end up worsening an already terrible trend, as the infection is associated with elevated IL-17a. IL-17a is a key molecule in both the innate and adaptive immunity that helps mobilize your immune system response during early infection. It’s been singled out as being involved in the thrombotic and vascular mechanisms of COVID-19 specifically.25
One October 2021 study26 suggested IL-17a acts as a silent amplifier of the COVID-19 immune response, resulting in some of the worst side effects associated with the infection. While pregnant women are universally instructed to get the COVID shot to protect themselves from the infection, there’s every reason to suspect the injection may cause far more harm than the infection itself.
If you get COVID while pregnant, you may or may not have a serious case of it, but if you take the shot, you have a 100% chance of suffering the effects of it, which for many include dramatically elevated levels of inflammation.
From my perspective, getting the COVID jab because you fear what COVID-19 might do to you and/or your baby is actually irrational, as your risk of adverse effects from the shot is exponentially higher than your risk of severe COVID-19 infection.
Autism Is a Multifactorial Condition
A number of other culprits could also be named, such as retroviruses (which the COVID shots can reactivate) and electromagnetic field (EMF) exposure. According to Judy Mikovits, Ph.D., a retrovirus family known as xenotropic murine leukemia virus-related viruses (XMRV) may play a causal role in autism.27
Disturbingly, one source for XMRVs is contaminated childhood vaccines. Mikovits details the history of this in her book, “Plague: One Scientist’s Intrepid Search for the Truth About Human Retroviruses and Chronic Fatigue Syndrome (ME/CFS), Autism and Other Disease.”
In previous interviews with me, Mikovits has also expressed concern that the COVID shots may activate latent XMRV infection. If it does, we could expect the autism rate to explode at an even more exponential rate than we’re seeing already.
I predict the COVID shots will be found to contribute to autism in a number of different ways. But even in the absence of these injections, it’s clear that environmental toxicities are wreaking havoc with our children’s health.
There’s no single answer to this problem. Since many different toxins can contribute, preventing autism must include the elimination of most toxic exposures.
Top suspects include childhood vaccines, the 10 chemicals listed earlier (glyphosate in particular), autoimmune antibodies, gut inflammation, retroviruses and EMF exposure. To this list, I would also add the COVID gene transfer injections, as they can be a source of severe inflammation and autoimmunity, and have been shown to have a direct adverse impact on neurology.
- 1, 3 Autism Society
- 2 National Autism Association
- 4 Yahoo News! December 7, 2021
- 5, 6, 8, 9, 10 Seminars in Pediatric Neurology October 2020; 35: 100829
- 7 Seminars in Pediatric Neurology October 2020; 35: 100829, Table 2
- 11 Curr Opin Investig Drugs May 2009; 10(5): 463-473
- 12 Molecular Psychiatry August 20, 2013; 18: 1171-1177
- 13 Science Daily August 29, 2021
- 14 Environmental Health Perspectives July 1, 2012; 120(7)
- 15, 16 Science Daily April 25, 2012
- 17 Journal of Molecular and Genetic Medicine, 2015;9:187
- 18 Medical Sciences, 2018;6(2):29
- 19 BMJ 2019;364:l962
- 20 Time March 20, 2019
- 21 Scientific Reports 9, Article number: 5987 (2019)
- 22 Immunity December 7, 2021 DOI: 10.1016/j.immuni.2021.11.005
- 23 MIT News December 9, 2021
- 24 The Picower Institute
- 25 Autoimmun Rev July 2020; 19(7): 102572
- 26 Biomedicine & Pharmacotherapy October 2021; 142: 111980
- 27 Plague: One Scientist’s Intrepid Search for the Truth About Human Retroviruses and Chronic Fatigue Syndrome (ME/CFS), Autism […], by Judy Mikovits
The Troubling Role of Glyphosate in COVID-19
Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2021/10/16/stephanie-seneff-glyphosate.aspx
Analysis by Dr. Joseph Mercola Fact Checked October 16, 2021
STORY AT-A-GLANCE
- Your body substitutes glyphosate for glycine, and in so doing, poisons your body’s machinery for creating proteins
- In normal physiology, processes in your mitochondria ensure deuterium depletion. If your mitochondria are damaged by glyphosate, they’re not going to be able to eliminate the deuterium properly and the buildup of deuterium may contribute to chronic disease
- Glyphosate may play an important role in cases of severe COVID-19. If you’ve accumulated a lot of glyphosate in your tissues, your immune cells will be impaired, making it difficult to clear the virus
- To avoid glyphosate exposure, the most important strategy is to eat certified organic foods whenever possible, and eat/drink more sulfur-containing foods, organic grass fed milk and butter, glacier water, animal fats and probiotic foods
- To help mitigate the toxic effects of glyphosate, you can take an inexpensive glycine supplement
This article was previously published February 28, 2021, and has been updated with new information.
In this interview, Stephanie Seneff, Ph.D., a senior research scientist at MIT, reviews the health impacts of glyphosate. She has just finished writing a book about glyphosate called “Toxic Legacy: How the Weedkiller Glyphosate is Destroying Our Health and the Environment,” which is expected to be published in June 2021.
For years, glyphosate was assumed safe and claims of toxicity were vehemently denied. But in recent years, studies on glyphosate have been demonstrating toxicity even at very low levels. Seneff also believes glyphosate exposure may be a key player in cases of severe COVID-19, which we’ll unravel in this interview.
Glyphosate’s Mechanism of Action
The “gly” in glyphosate actually stands for the amino acid glycine. The glycine amino acid in glyphosate has a methylphosphonate group attached to its nitrogen atom, which is responsible for its effects and toxicity.
After studying the research literature on glyphosate, Seneff has reached the conclusion that your body sometimes substitutes glyphosate for the amino acid glycine when it is constructing proteins, and this can have devastating consequences in some cases. The proteins created with glyphosate instead of glycine simply don’t work because glyphosate is much larger than glycine and also negatively charged, and as a result this alters important physical characteristics.
Monsanto’s own research, dating back to the late 1980s, shows that glyphosate accumulates in various tissues, even though they claim it doesn’t.1 The Monsanto researchers proposed that it was “incorporated into” the proteins in the tissues. This is not widely appreciated, even in the natural health community.
Now, if you have a distorted analog of glycine (in the form of glyphosate), the protein constructed from it is not going to work like it’s supposed to. In her book, Seneff details the amino acids in proteins that are most susceptible to damage because of what she calls a “glyphosate susceptible motif.”
“It’s really fascinating biology and so terrifying when you think of the potential consequences, if I’m right,” she says. “It matches so well with all the diseases that are going up dramatically in our society that I really think I’m onto something huge here.”
An aromatic amino acid called EPSP synthase is a critical enzyme that almost surely gets disrupted by glyphosate through this mechanism of substituting for glycine. This gets a bit technical, but it is important. The plant version of EPSP synthase binds a phosphate group in its substrate phosphoenolpyruvate at a site where there is a highly-conserved glycine residue (highly conserved usually means that it is critical for proper function).
It has been shown experimentally that, if you change the DNA code so that the glycine is substituted by an amino acid called alanine (one extra methyl group), the enzyme becomes completely insensitive to glyphosate at any concentration. It also takes a hit on phosphate binding because of the extra methyl group, but you can tweak another amino acid nearby to fix this problem, while still keeping its insensitivity to glyphosate.
Researchers from Dow-Dupont did exactly this to a maize version of EPSP synthase using CRISPR technology and were able to create synthetically a version of the maize’s own EPSP synthase that was completely resistant to glyphosate. The title of this paper is: “Desensitizing Plant EPSP Synthase to Glyphosate: Optimized Global Sequence Context Accommodates a Glycine-to-Alanine Change in the Active Site.”2
The shikimate pathway is the pathway that produces aromatic amino acids, which are essential to humans as we cannot create these amino acids in our body. The argument is we’re not susceptible to glyphosate because our cells don’t have EPSP synthase — in fact, they don’t have the entire shikimate pathway.
However, our gut microbes do have that pathway, and they use it to make essential amino acids for the host. So, our gut microbes are indeed affected by glyphosate, and when they’re damaged, our health can suffer in any number of ways.
But what might be an even more devastating problem with glyphosate is the way it probably messes up a large number of proteins that bind phosphate at a site where there is at least one, and often three, highly conserved glycine residues. Glyphosate slips its methylphosphonate group into the spot that is supposed to be where phosphate from the substrate fits snugly. Phosphate can’t bind because glyphosate is in the way.
The arguments for why glyphosate specifically disrupts proteins that depend on glycine for phosphate binding are described more fully in a paper Seneff published together with colleagues arguing that glyphosate is a major factor in kidney failure among young agricultural workers in Central America.3
The Importance of Deuterium
Laszlo Boros is a professor of pediatrics at UCLA and an expert on deutenomics, “the science of autonomic deuterium discrimination in nature.”4 After reading one of Seneff’s papers, he contacted her, suggesting she look into deuterium.
“I was blown away, and I immediately saw the connection to glyphosate,” she says. “This was a year ago in December, and I’ve just been reading everything I can on deuterium since then and hooking it to glyphosate. It’s just astonishing what I found, even, ultimately, [linking it] to COVID-19.
It’s been quite a year for me in terms of major breakthroughs in my understanding of how metabolism works and how it’s getting messed up by glyphosate, and then how that’s causing us to not be able to effectively deal with COVID-19.”
In normal physiology, your cells, specifically the mitochondria, function to help deplete your body of deuterium. Deuterium is a naturally occurring isotope of hydrogen. If you didn’t already know, deuterium is also known as heavy hydrogen, because it has a neutron in addition to the proton and electron in the hydrogen atom.
Provided your cell is healthy, it has deuterium-depleting enzymes and organelles that help remove deuterium from your cells. If your mitochondria are damaged by glyphosate, they’re not going to be able to eliminate the deuterium properly.
Deuterium is like iron in the way that it’s both essential in the right amounts and toxic in excess. Hydrogen is the smallest atom and by far the most common atom in your body. Deuterium, being a heavy hydrogen, has one extra neutron, in addition to the normal proton and electron that regular hydrogen has.
Now, your cells are surrounded by structured water, which is negatively charged and contributes to your body’s energy production by supplying deuterium-depleted hydrogen to lysosomes and mitochondria. The structured water is maintained by sulfates, which makes sulfate extremely important for health. Sulfate is made dysfunctional by glyphosate, which in turn destroys structured water, resulting in impaired energy production in the cell.5
“The mitochondria have [a] membrane, which has a part inside the membrane that’s really, really important,” Seneff says. “That’s where you have those protons, and you really don’t want it to be deuterons. This is what Laszlo brought home to me.”
How Your Body Creates Deuterium-Depleted Water
Endothelial NOS (eNOS) makes nitric oxide (NO), and for every molecule of NO that it makes, it produces two molecules of water, which are deuterium depleted. Stephanie believes the NO created by eNOS may act as a signal that deuterium-depleted water has been created. Interestingly enough, deuterium-depleted water is also created during the inflammatory process.
“The inflammation is there for a good reason, and the reason is to produce deuterium-depleted water,” Seneff says. “It’s all because the mitochondria are failing in their task of producing their own deuterium-depleted water, which they get in part through the structured water from the sulfate [and] through enzymes that are highly skilled at choosing hydrogen over deuterium …
NADH and NADPH are also fascinating. I’ve been chasing them through all the proteins. They are interesting because they are the carriers of that wonderful hydrogen that’s not deuterium. When you trace what’s doing what, where, you realize that the cytoplasm is producing NADH and handing it over to the mitochondria.
The mitochondria then take that H [hydrogen atom] off and throw it into the intermembrane space. So, the whole process ends up with the intermembrane space being assured that this is H [hydrogen] and not D [deuterium].
This is crucial because then those protons, once they build up, come back through the ATPase [ATP synthase] pump. If they are deuterons, they are going to wreck the pump … You release reactive oxygen species [that] break it, and of course, then you can’t make ATP.”
For clarification, the ATP synthase pump works like a mini-motor. When a hydrogen atom with one proton goes through it, it works flawlessly and generates ATP. If deuterium enters it, which has one neutron and one proton, making it twice the weight of hydrogen, it breaks that motor.
Interestingly, deuterium is everywhere, naturally, but your body has developed an intricate way to make it harmless by trapping it in the structured water, where it’s beneficial, as it actually supports the creation of structured water.
Problems arise when you cannot make enough structured water to sequester it all. Then, the deuterium gets loose, causing mitochondrial dysfunction, impairing energy production and contributing to chronic disease.
Glyphosate Damages Health in Many Ways
As noted by Seneff, glyphosate harms your health in a number of ways. For example, she cites a recent paper showing it causes endocrine disruption, which can lead to breast cancer, reproductive issues, obesity and thyroid problems.6
Another paper shows glyphosate sensitizes cells to be more receptive to cancer after exposure to other chemicals.7 “Glyphosate makes everything else more toxic than it would otherwise be,” Seneff says. “It disrupts your defense system against toxic chemicals.” Other research shows epigenetic and generational effects, even when no apparent problems can be found in the first generation exposed.8
Glyphosate also impairs flavoproteins — proteins that bind flavins. Many of these proteins play a crucial role in transferring hydrogen from NADH or NADPH to other molecules, essentially supporting the delivery of pure hydrogen to the mitochondria. Flavoproteins have a characteristic GxGxxG motif at the site where they bind phosphate in the flavins. The ‘G’ stands for glycine and the ‘x’ is a wildcard — any amino acid, including glycine.
This means they have at least three susceptible glycines at this critical region of the protein. Flavoproteins are molecules that facilitate the transfer of protons and electrons, and know how to avoid deuterium, by exploiting a special feature of hydrogen called proton tunneling.
All of them can be expected to be disrupted by glyphosate. A critical flavoprotein is succinate dehydrogenase, and several papers have shown it is adversely affected by glyphosate, Seneff says. It is the only enzyme that plays a role in both oxidative phosphorylation and the citric acid cycle in the mitochondria.
In addition to aromatic amino acids, the shikimate pathway is essential for riboflavin synthesis, and riboflavin, a B vitamin, is the main precursor to flavins. This means that riboflavin deficiency can be triggered from glyphosate exposure as well. Glyphosate also causes damage by:
- Increasing calcium uptake in cells, which causes toxicity to neurons
- Interfering with the ability to take glutamate out of your synapses
- Making manganese unavailable — This in turn disrupts and prevents glutamate from being turned into nontoxic glutamine after it’s removed from your synapses. The enzyme responsible for the conversion is also highly dependent on glycine, which could be replaced by glyphosate
Deuterium-Depleted Water May Be Central to Metabolism
According to Seneff, it appears deuterium-depleted water plays a central, hitherto unappreciated role in metabolism, as your body has so many ways to create it. For example, deuterium-depleted water is created through:
•Fatty acid synthesis and metabolism — The enzymes that synthesize fatty acids incorporate hydrogen that is carried by NADPH. This hydrogen atom has been carefully selected to be assured not to be deuterium. Interestingly, lipoxygenase is a protein expressed during conditions of stress, and according to Seneff, it has the greatest ability to select protons over deuterons of any protein.
It is highly upregulated in severe COVID-19 infection. It appears the virus triggers an increase in lipoxygenase because the virus captures linoleic acid (LA) in pockets in the viral membrane. However, lipoxygenase is not a flavoprotein, and it also doesn’t bind heme — this makes it resistant to damage from glyphosate. So, its activation becomes an alternative pathway to fix the mitochondrial deuterium problem.
SARS-CoV-2 picks up the omega-6 LA as it crosses the cellular membrane, and the LA then triggers the production of lipoxygenase that modifies the LA into leukotrienes — signaling molecules that bring in damaging macrophages.
But deuterium-depleted water is also produced in this process, by yanking two hydrogen atoms out of the fat and combining them with oxygen to make water. Note that this is just yet another way that excess LA damages your body, but with an ulterior motive that we often fail to appreciate.
•Sterol synthesis and metabolism — including cholesterol, vitamin D, cortisol, and sex hormones.
•Aromatic amino acid derivatives — including melatonin and neurotransmitters such as dopamine and serotonin, as well as thyroid hormone.
“All these molecules that go through these complicated steps are all focused on delivering deuterium-depleted water to the mitochondria,” Seneff says. “I mean, it’s an absolute obsession that the cell has.” She goes on to review how processes that may appear to have nothing but harmful effects are actually an effort to heal the body. This, for example, seems to be the case in COVID-19:
“I believe that whatever biology is doing, it’s doing it for a good reason. There may be damage, but there’s a good reason why you need that damage in order to survive long term. It’s trying to fix a problem that’s very serious, and that’s what I think is happening with [SARS-CoV-2].
Not only does it induce this lipoxygenase, which produces deuterium-depleted water, it then creates this inflammatory environment, which brings in the platelets and the macrophages, the immune cells and the stem cells. All these are having a big party in there in all this fluid that’s building up inside the lungs.
Meanwhile, it also increases the production of hyaluronic acid. Hyaluronic acid is able to trap deuterium-depleted water. It makes structured water. So, you get structured water inside the alveoli of the lungs, and then you get fluid water in the interstitial spaces.
The blood vessels are leaky, the capillaries are leaky. Everything’s coming out of the capillaries into this interstitial space where there’s this fluid water, and you’ve got this lipoxygenase making deuterium-depleted water.
So, you’re producing this environment of deuterium-depleted water, inviting the macrophages to come in, and the platelets release their mitochondria … the stem cells also come in and release their mitochondria, and then macrophages sweep up the mitochondria — and all this is happening in the interstitial space in the lungs where the fluid is. This is why you cannot breathe. You’re drowning.
Maybe one of the most important things platelets do is hang on to mitochondria that they can deliver to the macrophages under conditions of stress. So, what happens is all these mitochondria get released in that interstitial space, and the macrophages induce this macropinocytosis, where they actually sweep up the water and everything that’s in it and bring it inside the macrophage, including the mitochondria.
It’s actually been shown that platelets can release mitochondria into the environment, and macrophages can take them up and use them as perfectly functioning mitochondria. It’s astonishing. So, what they’re doing is restoring the mitochondrial health to the immune cells.”
Glyphosate Damage May Be a Factor in Severe COVID-19
As explained by Seneff, your immune cells are impaired by glyphosate, so the older you are, the more likely you’ve been exposed to glyphosate for decades and therefore have poorly functioning immune cells. Interestingly, Seneff points out that the comorbidities of COVID-19 — obesity, diabetes and high blood pressure — are also diseases whose prevalence is going up dramatically over time, exactly in step with glyphosate usage on core crops.
“So, I think it’s mostly about glyphosate,” she says. “If you’ve accumulated a lot of glyphosate in your tissues, you’re not going to do well with COVID-19, and that’s because [your body] is trying to repair the mitochondria in the immune cells so that the immune cells can actually clear the virus. If they can’t make ATP, they can’t do their job, and the virus flourishes.”
The key take-home message here is that this is yet another reason to clean up your diet to make sure you’re not exposed to glyphosate. It basically wrecks your immune cells, and the cascading damage that takes place in severe cases of COVID-19 appears to be your body’s response to salvage or repair those poorly functioning immune cells.
Dietary Recommendations
The answer to this problem is, first of all, to eat certified organic foods whenever possible. “We won’t buy it if we can’t find certified organic, and we’ve really seen health improvements since we’ve started doing that,” Seneff says. “I really swear by it, and I try to get all my friends to do the same. I think if you can eliminate glyphosate, you can really see great improvements in your health no matter what your problems are.” Other dietary recommendations include eating/drinking more:
| Sulfur-containing foods such as organic eggs and seafood | Organic grass fed milk and butter. Butter is one of the lowest deuterium foods available |
| Glacier water, which is naturally low in deuterium | Animal fats, which are also low in deuterium |
| Molecular hydrogen | Probiotics foods such as sauerkraut and apple cider vinegar |
To help “push” glyphosate out of your body and mitigate its toxicity, you can take an inexpensive glycine supplement. I take between 5 and 10 grams a day. It has a light, sweet taste, so you can actually use it as a sweetener.
“It makes sense because it’s basically going to outnumber the glyphosate molecules,” Seneff says. “Remember, glyphosate’s going to compete with glycine in building the protein. If there’s a lot of glycine around, then it’s much less likely that glyphosate will get in there.”
- 1 Uptake, depuration and bioconcentration of C-14 glyphosate to bluegill sunfish (Lepomis machrochirus) Part II
- 2 Journal of Biological Chemistry Volume 294, Issue 2, 11 January 2019, Pages 716-725
- 3 Journal of Environmental Research and Public Health 2019, 16, 2734
- 4 Lazlogboros.com
- 5 S Seneff and G Nigh. Sulfate’s Critical Role for Maintaining Exclusion Zone Water: Dietary Factors Leading to Deficiencies. Water 2019; 11: 22-42
- 6 Chemosphere 2020: 128619. [Epub ahead of print]
- 7 Front. Genet., 27 September 2019
- 8 Scientific Reports 2019: 9, Article number 6372
POWERFUL VIDEO: The “unspoken” COVID threat due to a poisoned food supply
Reproduced from original article:
https://www.naturalhealth365.com/glyphosate-and-covid-link-3957.html
by: Edit Lang, staff writer | August 31, 2021
(NaturalHealth365) Thanks to the tireless effort put forth by the mainstream media to brainwash the masses, millions now believe that the only way to protect against the invisible virus is by masking up, getting jabbed, and avoiding our fellow human beings. It doesn’t seem to matter that none of these measures are grounded in sound science, that the virus has never been isolated, or that (conventionally speaking) the disease in question has a 99.9x percent survival rate for the vast majority of the global population.
What appears to matter most is to keep the fear going and scare people into submission to taking a virus-based experimental gene therapy.
But, anyone awake realizes that there is something sinister about how governments, Big Tech, and Big Media colluded to silence words of wisdom and common sense questioning the official narrative. For example, no one can talk about the immune system and its critical role to serve as our line of defense against possible invaders – including those far more deadly than the virus causing COVID-19.
In addition, no health agency stresses the importance of living a healthy lifestyle to reduce our risk of mortality during the pandemic, nor are we warned against the dangers of toxic chemicals present in our food supply.
Powerful VIDEO: MIT Scientist reveals the hidden dangers of glyphosate toxicity and its detrimental impact on our health
In this video, Jonathan Landsman of NaturalHealth365.com talks to Stephanie Seneff, PhD, Senior Research Scientist at Massachusetts Institute of Technology (MIT), to uncover the many ways that glyphosate (RoundUp) destroy human health – including its potential adverse effect on our ability to fight off infections, such as the coronavirus.
According to Dr. Seneff, one of the key aspects of glyphosate toxicity is the destruction of innate immunity. Glyphosate weakens our innate immune system’s ability to ward off viruses – including the one thought to cause COVID-19. According to her explanation, in lieu of optimally functioning innate immunity, our “adaptive immune system has to kick in in a big way,” which can lead to the infamous cytokine storm and subsequent organ damage.
Stunning statistical correlations confirm link between increased use of glyphosate and rise in chronic diseases
Dr. Seneff points out that while correlation does not necessarily equal causation, it is difficult to deny that many chronic diseases have risen over time precisely in step with the dramatic increase in the use of glyphosate. Tragically, this correlation is particularly strong between the massive use of glyphosate on crops and cardiovascular disease, Alzheimer’s disease, autism, diabetes, and even certain types of cancers (thyroid and pancreatic).
Glyphosate adversely affects our cardiovascular system
If you think our immunity is the only system impacted by all the glyphosate-soaked foods we consume every day, think again! Our cardiovascular system suffers greatly too, yet, government health officials do not warn us about the dangers.
Watch this video and pay careful attention to the fascinating explanation for how glyphosate destroys the health of our vascular system.
Exposure to toxic glyphosate disrupts gut microbiome, causes digestive disorders, and undermines the immune system
In another segment of this captivating interview, Dr. Seneff explains how this seemingly innocent chemical sprayed widely on a multitude of conventionally grown crops harms our gut health, leading to multiple chronic conditions. Studies have confirmed that many chronic diseases start in the gut, including autism, Parkinson’s disease, and rheumatoid arthritis.
It is critical for anyone suffering from these diseases to eliminate foods contaminated or grown with glyphosate to restore the microbiome’s diversity.
Here is how GMOs inflict damage on our health
Soy, corn and sugar beets are some of the most common crops that are grown as GMO. Glyphosate-resistant crops are all over the food supply, and the government imposes little to no restriction on their use. Processed foods are usually loaded with GMO ingredients, and unfortunately, most people have no idea how harmful they are.
While it is important to eliminate processed foods to reduce your glyphosate exposure, you can still get exposed through other food sources. For example, while non-GMO wheat, chickpeas, oats, and lentils are generally healthy foods, they are likely sprayed with glyphosate right before harvesting – unless organically grown.
Don’t miss watching this video to learn the many other ways our glyphosate-tainted food supply causes unimaginable health damage – nutritional deficiencies, depression, anxiety, and even cancer.
Here are some simple tips to reduce your glyphosate exposure:
- Eat organic foods
- Go to local farmers markets and get to know the farmers
- Spend time in the kitchen
- Make cooking fun
We hope that bringing this interview to you helps put things into perspective and encourages you to view your health more holistically. So let’s share this interview far and wide and empower others to take simple steps to start living a healthier life – especially during the so-called pandemic.
Sources used for this article: