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Unlocking DMSO — The Forgotten Molecule That Makes Drugs Work Better, Safer, and Faster


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/07/04/unlocking-dmso.aspx


Analysis by A Midwestern Doctor     
July 04, 2025

unlocking dmso

Story at-a-glance

  • DMSO is an “umbrella remedy” capable of treating a wide range of challenging ailments due to its combination of therapeutic properties (e.g., reducing inflammation, improving circulation, and reviving dying cells)
  • One of DMSO’s unique properties is its ability to enter through the skin and carry anything it dissolves with it as it rapidly travels throughout the body, greatly enhancing the potency and viability of many pharmaceutical drugs
  • Because of this, numerous preparations over the years have combined DMSO with a commonly used medication, and in many cases, demonstrated safety and efficacy of the combination to drug regulators
  • Some of these DMSO combination therapies are able to treat challenging illnesses, such as significant musculoskeletal injuries, antibiotic resistant infections, persistent fungal and viral infections, chemotherapy resistant cancers, and chronic pain
  • More creative DMSO combinations (which can be produced at home) have been frequently used to successfully treat many challenging conditions (e.g., tinnitus, a wide range of eye issues, cancers, and uncomfortable scars)

DMSO is a remarkable naturally occurring substance that (provided it’s used correctly1) safely and rapidly improves a variety of conditions medicine struggles with — particularly chronic pain. For example, thousands of studies show DMSO treats a wide range of:

Injuries such as sprains, concussions, burns, surgical incisions, and spinal cord injuries (discussed here).

Strokes, paralysis, many neurological disorders (e.g., Down syndrome and dementia), and numerous circulatory disorders (e.g., Raynaud’s, varicose veins, or hemorrhoids), which were discussed here.

Chronic pain (e.g., from a bad disc, bursitis, arthritis, or complex regional pain syndrome), which was discussed here.

Many autoimmune, protein, and contractile disorders, such as scleroderma, amyloidosis, and interstitial cystitis (discussed here).

Head conditions, such as tinnitus, vision loss, dental problems, and sinusitis (discussed here).

Internal organ diseases such as pancreatitis, infertility, liver cirrhosis, and endometriosis (discussed here).

A wide range of skin conditions, such as burns, varicose veins, acne, hair loss, ulcers, skin cancer, and many autoimmune dermatologic diseases (discussed here).

Many challenging infections, such as shingles, herpes, chronic ear or dental infections, and osteomyelitis (discussed here).

Cancers and many complications from the illness and its treatments (discussed here).

In turn, since I started this series, it struck a chord, and I have received over 2,000 reports of remarkable responses to DMSO, and many readers have had for a variety of “incurable conditions.”

This begs an obvious question — if a substance capable of doing all of that exists, why does almost no one know about it? Simply put, like many other promising therapies, it fell victim to a pernicious campaign by the FDA, which kept it away from America despite decades of scientific research, congressional protest, and thousands of people pleading for the FDA to reconsider its actions. Consider for example, this 60 minutes program about DMSO that aired on March 23, 1980:

Understanding DMSO’s Combination Potential

DMSO’s effectiveness in treating a wide range of illnesses stems from its unique and diverse properties, many of which appear to target the root causes of disease — such as enhancing parasympathetic activity, improving circulation, regenerating senescent cells, providing potent anti-inflammatory effects, and blocking pain conduction. Sadly, despite hundreds of studies demonstrating these promising characteristics, the FDA has refused to recognize all but one property of DMSO.

In pharmacology, DMSO is often referred to as a “vehicle” that helps other drugs get into the body. Because of this, while DMSO only has one approved (intravesical) use in the United States, a variety of drugs are on the market that use DMSO as a “vehicle” to transport them in the body.

In short, when DMSO is given alone, it is “unsafe” and “unproven” but when combined with a patentable drug, it suddenly becomes “safe and effective.” Likewise, in package inserts, DMSO is typically described as a safe and inert ingredient (despite it often being the primary “active ingredient”).

DMSO’s ability to serve as a drug delivery system is due to its being a potent solvent with a variety of unique properties.

Membrane permeability — DMSO will pass through biological membranes without damaging them, which is extremely unusual.2 This property is believed to be due to its exchange and interchange with water in biological membranes.3 In addition to not harming the skin, when tested with other substances that could enter the brain, DMSO was not observed to alter the cells lining the blood-brain barrier or the brain tissue.4

Rapid distribution — Once it contacts the skin, DMSO rapidly spreads throughout the body. Within an hour of being applied to the skin, it can be found within the bones and teeth.5 Interestingly, DMSO does not penetrate tooth enamel or nails, which may explain why certain conditions affecting these structures require different approaches.6

Solvent properties — DMSO is a highly potent solvent that can dissolve a wide range of polar and non-polar substances (and hence is sometimes used to solubilize other drug products). If a substance is dissolved within DMSO, DMSO can typically bring it into the body. While a few other substances can also serve as vehicles, DMSO is the most potent in pharmacology (e.g., DMSO is more effective than propylene glycol at delivering topical steroids into the body7).

Enhanced circulation and cellular transport — Beyond simply transporting substances into the body, DMSO also greatly increases circulation. By taking the place of water (as it is small, can form hydrogen bonds, and is relatively polar) while being both fat and water soluble, it changes the permeability of the cell membrane, allowing new things to enter the cell and waste products to leave the cells.

As a result, DMSO is able to both spread what it transports throughout the body and significantly enhance the body’s innate ability to circulate what has already been absorbed (including to previously inaccessible areas).

This combination of properties enables the topical administration of drugs that would normally require injection, and in many cases, can significantly increase their potency because it penetrates deep regions of the body that pharmaceuticals typically have difficulty entering, or because it bypasses the cellular barriers that normally exclude foreign substances.

In turn, lower doses of drugs can frequently be used (reducing their toxicity) because they become more potent, and because DMSO combinations can be locally applied to bring a drug to a target region, rather than taking a standard oral dose that raises the entire body’s target concentration.

Specialized DMSO pharmaceuticals — These properties allow well established drugs to be combined with DMSO. For example, NSAIDs (which are also used to treat pain and musculoskeletal injuries) have a variety of side effects when consumed orally (e.g., fatal NSAIDs gastric bleeds killed over 16,000 Americans in 19998). However, when combined with DMSO, NSAIDs can be applied topically to the site of injury, thereby avoiding the risks of oral NSAID consumption.

One FDA-approved drug (Pennsaid) does just that, and in clinical trials, it was found to have minimal systemic toxicity. DMSO significantly enhances the efficacy of diclofenac (Pennsaid’s NSAID) while exhibiting much lower toxicity compared to oral diclofenac.9,10,11,12

Many other FDA approved pharmaceutical products utilizing DMSO further demonstrate its therapeutic versatility:

Mekinist, a targeted cancer therapy, uses DMSO to stabilize the drug and enhance its water solubility, possibly increasing tumor penetration.13

Prochymal, a stem cell product for preventing tissue rejection, uses 10% DMSO to preserve stem cells, as do many other stem cell products.14

Onyx, a liquid injected into blood vessels to seal leaks, uses DMSO to dissolve the polymer so it remains liquid until reaching problem areas. DMSO is chosen because it’s a uniquely safe substance capable of this function.15

Viadur is a non-degradable implant for prostate cancer containing Lupron dissolved in DMSO, designed to slowly release Lupron over a year.16 DMSO is essential because Lupron is otherwise difficult to dissolve, and DMSO preserves its stability while being nontoxic.

Note: Lupron is an incredibly toxic hormone eliminating drug used for prostate cancer which was adopted by urologists due to it being incredibly lucrative (which then led to it being repurposed for many other areas of medicine such as gynecology and blocking puberty in transgender children).

Critical Considerations

DMSO’s function as a vehicle and potentiator has enabled a variety of innovations for common medical therapies (e.g., pain-killers, antibiotics, and chemotherapy), which has inspired many others to experiment with these combinations. However, for anyone planning to do this, it is critical to understand the safety precautions that must accompany using DMSO in this manner.

Contamination risk — One of the major risks of DMSO is its potential to exacerbate the effects of a toxic substance already present in the skin, so it is crucial to clean the skin thoroughly before applying DMSO. The original investigator of DMSO learned this lesson the hard way when researching toxic pesticides.17

[Herschler] wanted to investigate whether certain highly toxic pesticides were soluble in DMSO. The researcher felt how soluble they were when he sprayed some of the solution onto his skin. DMSO transported the poison into the body within minutes. The poison worked: Herschler temporarily suffered from impaired consciousness and shortness of breath.

Remarkably, despite the immense potential harm, serious incidents are extremely rare, suggesting either that users are consistently careful about cleaning skin prior to DMSO applications or that the actual risk is limited to highly toxic substances.

Potentiation effects — Many agents become significantly more potent when mixed with DMSO, and in a few reports made rare side effects typically seen at higher doses manifest (something which has occasionally been reported with the more toxic antibiotics like fluoroquinolones or certain chemotherapy drugs).

With natural substances, this is generally not problematic (as their potency and toxicity are typically much less than pharmaceuticals). Still, it remains a real consideration (although I have not come across any reports of this injuring someone).

Size limitations — While DMSO can draw things inside the body, it can only do so for smaller molecules, with the size limit thought to be around 500 daltons (although there are numerous examples of larger drugs also being transported).

For this reason, DMSO tends to work well as a vehicle for individual drugs or chemicals but not larger proteins (e.g., peptides). Likewise, pathogenic organisms are far too big for DMSO to transport, so areas of application do not need to be disinfected prior to application.

Note: Below the skin, the transportation limit is much higher (e.g., evidence suggests DMSO can bring molecules larger than 70,000 Da through the blood-brain barrier, opening even wider possibilities for intravenous applications).18

Purity requirements — When making DMSO combinations, it’s essential to obtain pure ingredients, as many pharmaceutical and supplement preparations contain multiple ingredients beyond the primary active compound

Note: One of DMSO’s most promising combinations is with a common dye (hematoxylin) as this combination selectively targets tumors with no toxicity to normal tissue and has remarkable efficacy against a wide range of cancers. Unfortunately, hematoxylin is often mixed with heavy metals (to better stain tissues), illustrating the need to ensure pure substances with DMSO.

Leaching — As a solvent, DMSO can leach toxic chemicals (e.g., those added to the surfaces of plastics) and hence later bring them into the body. For this reason, it is advisable to avoid storing DMSO in plastic that is not DMSO resistant and to avoid mixing or preparing DMSO with plastic tools.

In most cases, DMSO only leaches plastic at concentrations about 20%, so if DMSO is diluted before putting it in contact with plastic many of these issues can be avoided. Likewise, many DMSO compatible materials exist for preparing DMSO combinations — all of which is discussed further here.

Note: Most implanted medical devices are not at risk of DMSO leaching them as it dilutes far below 20% by the time it reaches them and can contact their plastic components. The one exception are within dental implants, and for that reason, DMSO mouthwashes must always be sufficiently diluted.

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DMSO Drug Interactions

Given DMSO’s ability to potentiate pharmaceuticals, a critical question arises: is it safe to take alongside other drugs? The answer is nuanced:

What we know — Most pharmaceutical interactions, unfortunately, have not been studied. Fortunately (particularly since over 61% of Americans are on at least one medication19), significant reactions are rarely reported.

Generally speaking, the risk for potentiation is stronger the closer they are taken together (particularly when mixed together in an IV infusion) so it is generally advised to space DMSO and a pharmaceutical by at least two hours, and in the case of more toxic ones (e.g., fluoroquinolones and certain chemotherapies) by at least two days.

Note: DMSO can also mitigate many pharmaceutical toxicities, such as gentamicin’s kidney toxicity20 or many injuries caused by chemotherapy.

Most of the research into DMSO’s interactions was conducted during the initial trials in the 1960s, where it was discovered DMSO significantly potentiated alcohol and also potentiated barbiturates, corticosteroids, insulin, digitalis, nitroglycerin, quinidine sulfate, and chemotherapy21 (leading to lower doses sometimes being needed).

Since then, DMSO has also been observed to potentiate certain opioids (e.g., morphine patches), NSAIDs, anticonvulsants (e.g., gabapentin), and certain sedatives (e.g., trazodone). Users typically do not report potentiation of anticoagulants; however, as a serious risk might exist, it is advisable to monitor your coagulation parameters when using both concurrently.

Note: Insulin potentiation is hypothesized to result from DMSO’s protein refolding capacity restoring the functionality of insulin receptors.22

Conversely, DMSO has also been observed to reverse the effects of Botox, likely by neutralizing the toxin induced paralysis.

Therapeutic Synergies

Over the years, many remarkable pharmaceutical DMSO combinations have been developed for a wide range of medical applications. These include:

Antibiotics — Antibiotic resistance is a major problem in medicine. However, when combined with DMSO, many organisms that are chronic and debilitating or life threatening (e.g., tuberculosis) lose their resistance to antibiotics.

DMSO also makes it possible to reach infections such as those within the bones that are normally difficult to reach and otherwise require maintaining very high blood concentrations of the drugs to ensure this result. Finally, in many cases (both for cost and to protect the gut microbiome) being able to topically apply an oral or IV antibiotic can be immensely advantageous (e.g., for mastitis or Lyme disease).

Antifungals — Fungal infections are often located in areas that topical and oral antibiotics have difficulty penetrating. However, research shows combining an antifungal with topical DMSO can reach those infections and there are many reports of multiyear fungal infections quickly resolving from this combination.

Herpes and shingles — Some of the most potent antiviral medications have difficulty penetrating through a lesion to where the virus resides. However, once combined with DMSO they do, and many clinical trials have proven the efficacy of these antiviral combinations.

Corticosteroids — For issues within the body, steroids (which have significant systemic toxicity) must be injected or taken orally. When combined with DMSO, this is often no longer needed, and as DMSO potentiates steroids, much lower and far less toxic doses can be taken to address an autoimmune or musculoskeletal issue.

Chemotherapy — By potentiating chemotherapy, DMSO has been proven to cure chemotherapy resistant cancers, and in many cases does so with much lower doses being needed.

Recently, owing to the emerging popularity of using ivermectin for treating cancer (which sometimes produces spectacular results but typically fits best as a complementary therapy), physicians have begun combining ivermectin with DMSO into a paste and topically applying it over tumors. While data is limited, this appears to consistently work, and sometimes produces dramatic responses like this one James Miller MD recently shared with me:

“I had a patient with a thoracic sarcoma that was debilitatingly painful with growth through a couple of ribs and metastases to his skull base that became basically pain free after 2 days of topical DMSO-ivermectin. At his 2.5 week follow up, he was completely pain free and had returned to playing racketball.”

Note: Nothing comparable to do this can be done with conventional cancer options (and given the severity of that situation, what would be used is also fairly toxic).

Conclusion

As so many things can be combined with DMSO, the incredible things we’ve seen so far are only the tip of the iceberg, and only the most preliminary (but highly encouraging) data exists on many of them, as there is so much to research. For example, DMSO combinations have been shown to effectively treat a wide range of eye issues (e.g., eye strain, macular degeneration, glaucoma, and cataracts), traumatic injuries (e.g., whiplash) tinnitusuncomfortable scarsneuropathic pain and Lyme disease.

Likewise, DMSO combination therapies are not restricted to pharmaceuticals, and as such, over the years, the DMSO community has discovered hundreds of incredible natural DMSO combinations that revolutionize natural medicine.

Stanley Jacob, the father of DMSO who devoted his career to advancing the science of it, was driven by the recognition DMSO was not a new drug, but rather, like penicillin, a new therapeutic principle which redefined how medicine could be practiced. Fortunately, due to an extraordinary confluence of circumstances, we have now arrived in an era where it is at last (after more than a century) no longer possible to suppress natural healing methods.

People around the world are at last awakening to the Forgotten Sides of Medicine and the realization that the ways to find the cures we need is not “more research” but rather rediscovering what was already found (but not possible to profit off of). This is an incredibly exciting time and I am immensely grateful to be part of it with you.

Author’s Note: This is an abridged version of a longer article about DMSO combination therapies which goes into greater detail on the points mentioned here, many of the other combinations not covered (e.g., for tinnitus or vision loss), and provides guidance for preparing the combination therapies. That article, along with resources and protocols for obtaining and using DMSO can be read here.

A Note from Dr. Mercola About the Author

A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD’s exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD’s work, be sure to check out The Forgotten Side of Medicine on Substack.

The History and Therapeutic Mechanisms Of Chlorine Dioxide

Reproduced from original article:
https://pierrekorymedicalmusings.com/p/the-history-and-therapeutic-mechanisms

Chlorine dioxide was discovered over 200 years ago. It’s use has steadily expanded into many industries and therapeutic applications despite a near global regulatory blockade on clinical research.

Pierre Kory, MD, MPA

Jan 27, 2025

I believe that my writings on chlorine dioxide are the most important (and the most dangerous) work I have yet done on Substack. Although several experts have written extensively on this topic previously (here, here, and here), this similar effort of mine simply results from my wish to become as knowledgeable as possible about this critically important therapeutic (there is no better way to do so than personally researching and writing about a topic).
This is the 3rd in my ongoing series of posts. In the first two I presented the political context in which chlorine dioxide has been attacked during Covid (“Trump’s Bleach Conference”) and in the 2nd post I detailed the success achieved by Bolivia’s national chlorine dioxide program against Covid.
In this post I will review its discovery, chemical properties, industrial applications, and therapeutic mechanisms. Upcoming posts will cover the history of the attacks faced by the pioneering researchers and practitioners, followed by a review of the safety studies of oral ingestion and a compilation of studies showing efficacy in a number of diseases. Be sure to subscribe so as not to miss out on these critical upcoming posts.
Ultimately, what me and my growing network of clinical and scientific experts of this therapeutic compound want to achieve, is for the FDA (and the copycat regulatory agencies worldwide) to lift its restrictions on performing clinical research trials of chlorine dioxide in human diseases. If anyone from MAHA is reading this right now (and I know some are), please add chlorine dioxide (and DMSO) to the list of therapies currently being suppressed by the FDA that need to be reversed (RFK Jr listed more than a dozen other such therapies in the below recent tweet):

Note that, in the below, many (but not all) references were found from the superlative theuniversalantidote.com’s website, from their “interactive reference guidebook” document.

Chlorine Dioxide – What It is, What It Isn’t

Chlorine Dioxide is a small, volatile and strong molecule consisting of 1 chlorine atom and 2 oxygen atoms.

  • It is a gas at normal temperatures and pressures.
  • Yellowish/green color and has an odor similar to that of chlorine.
  • Denser than air and is water soluble at standard temperatures and pressures up to 2500ppm.
  • Explosive in air at concentrations >10%. It is therefore normally generated in-situ (on-site) within an aqueous solution at <0.3%
  • Chlorine dioxide is a biocide. This means it kills all bacteria, viruses, and fungus on contact through a process of oxidization.

Chlorine dioxide was initially discovered in 1814 by Sir Humphrey Davy and was commercially produced in 1940 as a bleaching agent. It is labeled as a strong oxidizing agent, microbicide, and antiseptic. Based on these references here and here, chlorine dioxide is also known to have the ability to “neutralize various toxins, pesticides, herbicides, and pharmaceuticals contaminating drinking water.”

As an added bonus, it can do all of that without producing any harmful organic compounds as occurs with nearly all other disinfectants (like bleach – which contrary to FDA “warnings,” chlorine dioxide certainly is not).

Chlorine dioxide is more effective as a disinfectant than chlorine in most circumstances against waterborne pathogenic agents such as viruses, bacteria, and protozoa – including the cysts of Giardia and the oocysts of Cryptosporidium.

Chlorine dioxide has been extensively studied within multiple fields (commercial, industrial, healthcare) and by multiple entities including: EPA, HHS, USDA, CDC, NIH, NASA, DOD, independent laboratories, and universities worldwide.

Chlorine dioxide is registered as a sterilizer and biocide and is used to sterilize medical facilities and laboratories including BSL-3 and BSL-4 labs which handle the world’s most deadly pathogens. It was used to decontaminate the Senate offices in 2001 after the anthrax attack, and was also used in Ebola hot spots.

From this systematic review paper on chlorine dioxide as a disinfectant:

Different chemical structures with properties of disinfectants have been identified. These chemical structures include alcohol, aldehydes, anilides, biguanides, bisphenols, diamidines, halogen-releasing agents, halophenols, heavy metal derivatives, peroxygens, quaternary ammonium compounds, phenols, and cresols. However, each disinfectant attacks different target areas of the micro-organisms. Disinfectants can be divided into two broad groups: oxidizing and non-oxidizing disinfectants. Disinfectants containing halogens such as chlorine, iodine, and oxygen releasing materials are called oxidizing disinfectants, while disinfectants that bond to structures such as quaternary ammonium compounds and amphoterics are known as non-oxidizing disinfectants.

Oxidizing agents like chlorine dioxide are chemical compounds that accept electrons from “electron donors.” This is important because relative to chlorine dioxide, all pathogens (disease causing organisms or substances) are electron donors.

So what happens to chlorine dioxide after it reacts and oxidizes the pathogens? In aqueous systems, chlorine dioxide eventually decomposes into generally safe byproducts that naturally occur in our environment, i.e. chloride ions (like in table salt), oxygen (O₂), and other non-toxic residues.

From Chat GPT when asked to contrast chlorine dioxide with bleach:

Chlorine dioxide and bleach (sodium hypochlorite) are both powerful oxidizing agents commonly used as disinfectants, but they differ significantly in their chemical structure, mechanism of action, and applications. Here’s how they compare:

1. Chemical Composition

  • Chlorine Dioxide (ClO₂): A gas at room temperature, typically dissolved in water for use. It is a single molecule composed of one chlorine atom and two oxygen atoms.
  • Bleach (Sodium Hypochlorite, NaOCl): A liquid solution containing sodium hypochlorite as the active ingredient, along with water and small amounts of other chemicals.

2. Mechanism of Action

  • Chlorine Dioxide: Kills microorganisms by disrupting their metabolic processes and breaking down cell membranes and proteins. It primarily reacts with organic matter through oxidation.
  • Bleach: Also acts as an oxidizer, generating hypochlorous acid (HOCl) in water, which destroys bacteria and viruses by disrupting their enzymes and proteins.

3. By-products

  • Chlorine Dioxide: Produces fewer harmful by-products, primarily chlorite and chlorate ions (initially), which are less persistent in water systems compared to bleach by-products.
  • Bleach: Can produce potentially harmful chlorinated organic compounds (e.g., trihalomethanes and chloramines), especially when reacting with organic matter in water. (Editorial note: this is extremely important, trihalomethanes are suspected carcinogenic disinfection by-products[ associated with chlorination of naturally occurring organics in raw water.

4. Effectiveness

  • Chlorine Dioxide: Remains effective over a wide pH range (4–10) and is less affected by the presence of organic matter, making it suitable for challenging disinfection tasks.
  • Bleach: Its efficacy decreases significantly outside a pH range of 6–8 and in the presence of organic matter.

5. Applications

  • Chlorine Dioxide:
    • Water treatment (municipal, industrial, and potable water systems).
    • Food and beverage sanitation.
    • Medical disinfection and biofilm removal.
  • Bleach:
    • Household cleaning and laundry.
    • Pool and spa disinfection.
    • Surface disinfection in healthcare and other settings.

6. Safety and Stability

  • Chlorine Dioxide: Typically generated on-site because it is unstable as a concentrated gas and can decompose explosively. However, it is considered safer for certain applications due to fewer toxic by-products.
  • Bleach: Stable in liquid form but degrades over time, particularly when exposed to light and heat. It has a strong, recognizable smell and can be irritating to skin and respiratory systems.

7. Odor and Residue

  • Chlorine Dioxide: Has a less pronounced odor and does not leave a strong chemical residue or taste in treated water.
  • Bleach: Has a strong chlorine smell and can leave noticeable chemical residues.

Summary:

While both are effective disinfectants, chlorine dioxide is often preferred for applications requiring minimal by-products and effectiveness in diverse conditions, whereas bleach is more common for general-purpose household and industrial disinfection.

TIMELINE OF ITS ADOPTION ACROSS INDUSTRIES

Taken from pioneer Jim Humble’s website, here I provide a short paraphrased history of its use in industry where I also dug up the references:

1811: Chlorine dioxide is discovered by Sir Humphrey Davy, when he adds sulfuric acid (H2SO4) to potassium chlorate (KClO3). In the early 1900’s it was recognized as an antimicrobial biocide and became known for its disinfectant properties.

1930’s: Due to concerns about the logistics of safely transporting the gas, sodium chlorite began to be manufactured as a relatively safe precursor chemical, and the industries using chlorine dioxide would then generate the gas onsite as needed. Because of chlorine dioxide’s solubility in water, it starts being used as a water treatment.

1944: First commercial application. Used as a biocide/taste and odor control agent in domestic water at Niagara Falls in the USA.

1950’s: Increasing use of chlorine dioxide in water treatment plants and swimming pools in the U.S.A. Likewise it is discovered that chlorine dioxide destroys biofilm, the algal slime that collects in cooling towers, among other places and harbors harmful bacteria. Chlorine bleach by contrast cannot kill biofilm.

1956: Brussels, Belgium, switches to chlorine dioxide from chlorine for its drinking water disinfection operations. This marks the first large scale use of chlorine dioxide for potable water treatment.

1967: The Environmental Protection Agency (EPA) of the United States first registers chlorine dioxide as a disinfectant and sanitizer. The registration is for chlorine dioxide in the liquid form. Indicated uses include food processing (!), handling and storage plants, bottling plants, washing fruit and vegetables (!), sanitizing water, controlling odors, and treating medical wastes.

1970’s: The EPA begins recommending using chlorine dioxide instead of chlorine bleach to treat water. Hundreds of municipal water systems successfully convert to chlorine dioxide. This happens across the United States and Europe; more so for the latter. The conversion is catalyzed by a safer environmental profile of chlorine dioxide over chlorine, because chlorine dioxide does not produce any harmful byproducts, as does chlorine bleach.

1977: Three thousand municipal water systems achieve biological control using chlorine dioxide (EPA document here)

1980’s: Chlorine dioxide gradually replaces chlorine in many industries – in the pulp and paper industry as a bleaching agent, in industrial water treatment as a biocide and as an odor control agent, in food processing as a sanitizer.

1983: The EPA recommends chlorine dioxide as a solution for the problem of trihalomethanes (THMs). When chlorine is used to disinfect water and make it potable (chlorination), THMs are produced as a by-product. THMs have been linked to cancer (i.e., they are carcinogenic). Chlorine dioxide does not produce THMs.

1988: The EPA registers chlorine dioxide as a sterilizer. This means chlorine dioxide is both safe and effective to use in hospitals, healthcare facilities, and laboratories.

1990: Use of chlorine dioxide as a disinfectant, sanitizer and sterilizer grows across many industries and countries. Some of the industries are the beverage industry, fruit and vegetable processing plants, pulp and paper industries, and industrial waste treatment sites. These industries are spread across the United States, the United Kingdom and Europe.

2001: The Federal Emergency Management Agency (FEMA) and other government agencies use chlorine dioxide to decontaminate buildings contaminated with Anthrax. The chlorine dioxide was completely effective against the tiny Anthrax spores. The buildings, walls and furnishings suffered no damage from the treatment.

2005: FEMA again uses chlorine dioxide. It is used to eradicate mold infestations in homes damaged by the flood waters from Hurricane Katrina. After a 12-hour treatment, a New Orleans restaurant is able to banish all mold inside without rebuilding.

2010: The United States Food and Drug Administration issue a warning on using the chlorine dioxide formulation called Miracle Mineral Solution (MMS – made by combining sodium chlorite with hydrochloric acid) and pioneered by Jim Humble in his numerous treatment protocols. The FDA repeatedly describes it as industrial bleach while at the same time approving chlorine dioxide for use in mouthwashes, toothpastes, and as a food service disinfectant, citing it as being a better alternative than chlorine.

2014: The Centers for Disease Control (CDC) registers ProKure V and PERFORMACIDE® as disinfectants against the Ebola virus. Both contain chlorine dioxide. ProKure V claims it “begins to kill pathogens in a matter of seconds, whereas other commonly used, more traditional disinfectants take minutes. The rapid speed in which ProKure V kills pathogens makes it a product of choice for helping contain infectious-disease outbreaks and keeping public facilities cleaner and safer for everyone.” Chlorine dioxide is a potent virucide.”

EFFICACY AND SAFETY AS A BIOCIDE

Chlorine dioxide is one of, if not the fastest known and “complete spectrum” disinfectants, killing all forms of bacteria (aerobic, anaerobic, gram positive and negative), viruses, fungi and yeast, typically within a minute of contact, (spores a little longer), and notably without damage to animal cells, or even tissue culture cells.
In this mouse study (know that mice are more sensitive than humans to toxicities for many but not all compounds), they found that at concentrations between 5 and 20 ppm (this concentration becomes highly relevant in a later post when I discuss safety of oral treatment dose concentrations), chlorine dioxide killed almost all of the bacteria and fungi present while no damage to lung cells, eyes, or other organs was observed, even when 40ppm was added to their drinking water sub-chronically. The study concluded “chlorine dioxide showed favorable disinfection activity and a higher safety profile tendency than in previous reports.”

This is a very short list of papers showing in vitro and/or in vivo (animals) efficacy against a number of viruses and bacteria (more on this in a later post).

Typhoid, Norovirus, Hepatitis C virus, HPV, HIV, Influenza A Virus, E.Coli, Listeria, Rotavirus, Mycobacterium Avium, Hepatitis A Virus, staph aureus, also hospital pathogens like Acinetobacter baumannii, Escherichia coli, Enterococcus faecalis, Mycobacterium smegmatis, and Staphylococcus aureus.

Moving away from in vitro data in order to show that it can cure infectious disease in animals (in vivo study), in a randomized controlled trial from 2008 they exposed 10 mice to aerosolized influenza A and aerosolized chlorine dioxide at (0.03 ppm) simultaneously for 15 minutes. A control group of 10 mice were exposed to only the aerosolized influenza A for 15 minutes. Sixteen days after exposure, none of the mice exposed to the chlorine dioxide influenza A group had died, but 7 out of 10 mice in the influenza only control group died. That is a 70% fatality for the mice that did not receive aerosolized chlorine dioxide. Did you catch that? Extremely low doses of chlorine dioxide protected 100% of those mice from influenza.

Moving past in vitro and in vivo trials, in a later post I will review the efficacy of chlorine dioxide in the treatment of infectious and other diseases in humans. There I will provide a compilation of all published human clinical trials and studies (which are artificially few due to the suppression of clinical research using chlorine dioxide.

A comprehensive list of all organisms it has been studied and shown efficacy against is beyond the scope of this post, however, know that in a 2010 study, concentrations ranging from 1 to 100 ppm inactivated ≥ 99.9% of the viruses with a 15 sec treatment. The antiviral activity of CD was approximately 10 times higher than that of sodium hypochlorite which is standard bleach.

NASA actually referred to chlorine dioxide as “A Universal Antidote” back in 1988 (p.118 from this Annual Report), where these statements appear:

  1. The special properties of the Alcidem formulation, which has been approved by U.S. regulatory authorities, enable it to destroy mold and fungus, as well as bacteria and viruses, with minimal harm to humans, animals or plants
  2. NERAC conducted a computer search of more than a dozen databases and uncovered scores of applications, among them treatment of viral, fungal and bacterial infections in animals; treatment of human skin diseases; disinfection and sterilization of medical facilities;
  3. The University of Connecticut Medical School is studying the effects of the Alcide compound on human wound healing and scar tissue suppression.
  4. At Israel’s Hebrew University Dental School, trials are in progress on a plaque reducing mouthwash and in England researchers are meeting success in human clinical trials of treating herpes and other sexually transmitted diseases.

I cannot over emphasize the importance of the above NASA document from 1988. In it, they admit that it treats a broad range of infections in animals, aids in wound healing (I have a lot on that later), and was having success in treating herpes and other STD’s. Never forget this when you read statements from regulatory agencies across the world where they repeatedly warn that it is a “toxic bleach,” “bleach like substance,” and is “dangerous for ingestion.” Absurd.

Also take note of the fact that NASA never refers to it again in such a positive way. The next mention by NASA was in 1991 when referring to its use in the space shuttle where they caution of the risk of developing hemolytic anemia and disturbing thyroid function (such risks are negligible to non-existent in clinical practice).

Therapeutic Mechanisms Of Action

In this post, Andreas Kalcker describes the “dual properties” of CDS:

It possesses the unique ability to effectively oxidize pathogens that exhibit an oxidation-reduction potential (ORP) lower than its own ORP of 0.95V. This means that it can target and neutralize various harmful microorganisms, including bacteria, viruses, and fungi, by disrupting their cellular processes and ultimately leading to their demise.

At the same time, CDS also functions as a powerful reducing agent, as it can interact with and reduce harmful free radicals that have higher ORPs—such as hydroxyl radicals (OH-) which possess an ORP of 2.8V. In this process, chlorine dioxide transforms these detrimental radicals into harmless water molecules. This dual functionality is particularly important in the context of therapeutic applications, as it allows CDS to both eliminate harmful agents while simultaneously protecting healthy cells from oxidative stress.

From this masterful review article in the University of Guadelajara journal on mechanisms of chlorine dioxide, they report even more broadly systemic therapeutic mechanisms:

  • low concentrations of ClO2 can protect erythrocytes (red blood cells) from oxidative stress while inhibiting myeloperoxidase (MPO)-mediated excessive hypochlorous acid (HClO) production, thus reversing inflammatory responses and macrophage activation.
  • increases the expression of heme-oxygenase (HO-1), protects cells from death caused by hydrogen peroxide (H2O2), enhances the expression and activities of antioxidant enzymes, such as superoxide dismutase, catalase and glutathione peroxidase, and contributes to the resolution of the inflammatory process.
  • It promotes apoptosis (programmed cell death) in neutrophils, which helps resolve inflammation effectively
  • It has demonstrated anti-inflammatory responses by inhibiting macrophage activation in humans, thus reducing inflammation
  • Here it is important to review the different types and functions of macrophages (our immune system’s first line of defense against toxins and pathogens) :

    Monocytes are bone marrow derived precursors of tissue macrophages that are critical effectors of wound healing, clearance of bacteria and cellular debris and induction and resolution of inflammation. Macrophages that are associated with classical inflammation are termed M1 and those cells produce factors such as TNF-α, IL-1 and other proinflammatory factors. Macrophages that are associated with reversal of inflammation and suppression of immune responses are termed M2. In the context of ALS pathogenesis, the M2 macrophage phenotype within the spinal cord is associated with normal function, whereas the appearance of new M1 type macrophages within the spinal cord is associated with disease progression.

    These data suggest that systemic macrophage associated inflammation may play a significant role in ALS disease progression.“ In this study of a chlorine dioxide precursor in ALS, they report “these mechanisms of downregulation transform inflammatory monocytes/macrophages from a proinflammatory to a basal phagocytic (wound healing) state.”

    I will cover the studies showing improved survival and function in ALS patients in a later post.

  • taurine-chloramine is a product of activated neutrophils and represents the most relevant functional product formed under the influence of chlorine dioxide. This molecule activates nuclear factor erythroid 2 (Nrf2), (this transcription factor regulates the inducible expression of numerous genes for detoxifying and antioxidant enzymes), and inhibits production of pro-inflammatory cytokines.
  • In a study of a different precursor, they report, “Of importance, a single dose of NP001 (a patented formulation of chlorite) caused a dose-dependent reduction in downregulation of CD16-expressing inflammatory macrophages in blood.”
  • In this study, they found that the above WF10 (another patented formulation) exerts potent immune-modulatory effects through generating endogenous oxidative compounds such as taurine chloramine. Proliferation and IL-2 production of anti-CD3 stimulated PBMC were inhibited by WF10, as was the nuclear translocation of the transcription factor NFATc.
  • In another study of the NP001 proprietary formulation of pH stabilized, purified chlorite, they found that in the presence of heme-associated iron, presumably from the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex on the surface of phagocytic cells, it is converted from a prodrug through a hypochlorite intermediate, to an intracellular form of taurine chloramine (TauCl). TauCl is a long-lived effector molecule within macrophages that down-regulates NF-kB expression and inhibits production of pro-inflammatory cytokines in part through activation of heme oxygenase-1 (HO-1). A phase 1 controlled trial of NP001 in patients with ALS demonstrated the safety, tolerability, and dose dependent down-regulation of monocyte activation.

More therapeutic mechanisms:

Taken from this Andreas Kalcker substack post, he describes the effects of chlorine dioxide solution (CDS) using venous blood gas analysis:

  • The blood pH became more alkaline, indicating a reduction in acidity and an increase in basicity.
  • Blood oxygen levels increased, suggesting enhanced oxygenation throughout the body.
  • The concentration of carbon dioxide (CO₂) in blood decreased, implying effective CO₂ elimination via respiration.
  • There was an observable improvement in acid-base balance, particularly in base deficit, reflecting better pH regulation within the body, essentially reducing metabolic acidity, frequently a fundamental factor in numerous modern diseases
  • Blood glucose levels normalized, with reductions in hyperglycemia noted in other cases.
  • A significant decrease in blood lactic acid levels was observed, indicating improved removal of metabolic waste products.

Based on the above and considering the molecular composition of chlorine dioxide (two atoms of oxygen), Kalker argues in his mechanisms of action post here (where I paraphrase for brevity:

“chlorine dioxide transports oxygen to all parts of the body where water is present. The bound oxygen dissociates in the presence of excess protons in areas of disease (like spike protein). The released oxygen optimizes the saturation of hemoglobin in the red blood cell and thus improves oxygen delivery to the most acidic cells and their compromised mitochondria first, while the chlorine ion (not chloride) eliminates pathogens or acidic toxins and restores pH balance. This improvement in cellular oxygenation is thought to be yet another positive therapeutic mechanism for reversing disease.

Images depicting the effects of CDS on blood on a Nikon Phase contrast Microscope:

Effects of CDS in Human Blood under phase contrast microscope

In these phase contrast microscopy images above, the impact of CDS on small red blood cells is clearly visible. Initially, the cells were highly agglutinated and oxygen-deprived. Following the infusion of CDS at a maximum concentration of 3000 ppm from the left side, immediate signs of oxygenation can be observed. After a mere 12 minutes, all blood cells exhibit optimal oxygenation levels.

**As a pulmonologist, I don’t know how you can “see” improved oxygenation, although it can be inferred by the dramatic increase in the exposed surface area of each blood cell as they de-aggregate.

Overall, studies and treatment experiences reveal that treatment with chlorine dioxide:

  1. is broadly antimicrobial against nearly all infectious pathogens
  2. reduces inflammation
  3. prevents scarring
  4. aids in wound healing
  5. is non-toxic when orally ingested (in appropriate concentrations)
  6. reduces oral plaque
  7. treats oral atrophic candidiasis
  8. is a potent deodorizer
  9. has in-vitro anti-cancer cell effects, stimulates an in-vivo anti-cancer cell immune response and is also effective when injected intra-tumorally, or via a combination of oral, enema, and IV administration.

This combination of properties is not found in any other compound. The therapeutic uses for chlorine dioxide are endless. And therein lies the problem. Stay tuned for my upcoming post which compiles the studies and trials in a diverse set of human diseases.


** Please know that I am not recommending that anyone use chlorine dioxide orally given it is not FDA approved for oral ingestion in any medical condition, nor has it been approved by any foreign regulatory agency, nor is it classified as a food supplement. What I am trying to do is amass the critical information needed to petition the “new” FDA (and other regulatory agencies worldwide) to remove their restriction on performing human subjects research with orally ingested chlorine dioxide.

DMSO Transforms the Treatment of Infectious Diseases


Reproduced from original article:
https://articles.mercola.com/sites/articles/archive/2025/01/17/dmso-infectious-diseases.aspx


Analysis by A Midwestern Doctor     
January 17, 2025

dmso infectious diseases

STORY AT-A-GLANCE

  • Dimethyl sulfoxide (DMSO) is a safe, naturally occurring substance with properties that make it effective for treating various medical conditions, including pain, injuries, wounds, strokes, spine injuries, autoimmune disorders, cancer, and internal organ diseases
  • DMSO has broad antimicrobial properties, protects against microbial toxins, combats antibiotic resistance, and helps deliver healing deep into the body to treat otherwise inaccessible infections
  • DMSO studies have generated evidence supporting its role in treating cancer and autoimmune disorders through its unique antimicrobial properties
  • DMSO is highly effective against viruses like herpes and shingles, as well as conditions like feline panleukopenia in cats
  • DMSO also proves valuable in treating persistent fungal and parasitic infections

Introduction

DMSO is a remarkably safe and naturally occurring substance (provided you use it correctly1) that rapidly improves a variety of conditions medicine struggles with — particularly chronic pain. For reference, those conditions included:

Strokes, paralysis, a wide range of neurological disorders (e.g., Down Syndrome and dementia), and many circulatory disorders (e.g., Raynaud’s, varicose veins, hemorrhoids), which I discussed here.
A wide range of tissue injuries such as sprains, concussions, burns, surgical incisions, and spinal cord injuries (discussed here).
Chronic pain (e.g., from a bad disc, bursitis, arthritis, or complex regional pain syndrome), which I discussed here.
A wide range of autoimmune, protein, and contractile disorders such as scleroderma, amyloidosis, and interstitial cystitis (discussed here).
A variety of head conditions, such as tinnitus, vision loss, dental problems, and sinusitis (discussed here).
A wide range of internal organ diseases such as pancreatitis, infertility, liver cirrhosis, and endometriosis (discussed here).
A wide range of skin conditions such as burns, varicose veins, acne, hair loss, ulcers, skin cancer, and many autoimmune dermatologic diseases (discussed here).

In turn, since I started this series, it struck a cord and I have received over 1400 reports of remarkable responses to DMSO many readers have had (compiled here).

This begs an obvious question — if a substance capable of doing all of that exists, why does almost no one know about it? Simply put, like many other promising therapies, it fell victim to a pernicious campaign by the FDA which kept it away from America despite decades of scientific research, Congressional protest, and thousands of people pleading for the FDA to reconsider its actions. Consider for example, this 60 Minutes program about DMSO that aired on March 23, 1980:

DMSO and Infectious Diseases

DMSO has a variety of unique therapeutic properties. Some of those make it incredibly well-suited to addressing microbial infections. For example:

While nontoxic, it has an antiseptic effect that is harmful to microorganisms, especially the smallest ones. This property appears to be the most beneficial for herpes, shingles, and complex conditions with a microbiological component.

It can remove the antibiotic resistance of bacteria. This is particularly helpful in widespread problematic infections that have gradually developed a resistance to many existing antibiotics (e.g., tuberculosis) and challenging infections that are not responding to antibiotics (e.g., ones that would otherwise require an amputation).

It can deliver antimicrobial agents to areas that are typically difficult to reach (e.g., deep in a bone) and also directly to regions that would otherwise require a systemic application of the medication.

It can increase circulation to many parts of the body, something which is often critical for resolving illnesses (as a healthy blood supply allows the immune system to enter and heal diseased areas). Likewise, pretreatment with DMSO has been shown to increase the immune system’s ability to resist a subsequent infection.

Much in the same way DMSO protects cells from a wide variety of lethal stressors,2 it can also protect them from the harmful effects of bacterial toxins and can mitigate the toxicity of antimicrobial agents taken for a prolonged period.

In short, DMSO can transform the management of infectious diseases.

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Shingles and Herpes

Since many people struggle with Herpes (HSV-1 or HSV-2) and Shingles (Herpes Zoster), especially the pain which follows shingles (known as post-herpetic neuralgia or PHN), DMSO has been extensively studied for these uses. In turn, DMSO was found to significantly improve those conditions (and canker sores3), particularly when combined with idoxuridine (IDU), an antiviral that has poor penetration into tissues (and hence does not work alone).

Herpes simplex

A 1965 study4 used 1% IDU in 90% DMSO (and 10% distilled water) in 7 patients with severe cutaneous infections and noted significant improvement in all herpes cases, with the only side effect being slight skin irritation from the solution.

A 1966 RCT5 (randomized controlled trial) of 21 patients with recurrent herpes found DMSO halved the durations of outbreaks, and when given with 5% idoxuridine, cut it to a third (with similar results also found in a 1967 study6).

A 1983 study7 found that DMSO effectively brought acyclovir (ACV) into the skin, caused a moderate reduction in herpes lesions, and dramatically reduced them when combined with acyclovir.

A 1990 RCT8 gave 80% DMSO mixed with 15% IDU to 301 immunocompetent female patients. The duration of pain was reduced by 2.6 days and the healing time to normal skin by 2.3 days.

A 2002 cell study9 found 0.65% DMSO reduced herpes viral replication by 50%.

Note: DMSO also helps herpes fever blisters, and DMSO with IDU has been reported to be effective in treating HSV whitlow (herpes on the fingers).10

dmso herpes face

Shingles and Post Herpetic Neuralgia (PHN)

In 1967, a German investigator reported DMSO yielded generally good results in 10 of 11 shingles and PHN cases11 (with similar results being found in another 1967 study12).

Two 1970 RCTs showed that IDU in DMSO was at reducing the duration of pain and healing in shingles.13 The patients were delighted, for the pain disappeared within a median of two days.

In 1971, Dr. William Campbell Douglass conducted a study of 41 patients with shingles and PHN of whom 73.3% had a good response to DMSO and 13.3% had a fair response.

A 1974 RCT14 of 118 shingles patients and a 1992 RCT15 of 171 shingles patients found DMSO and IDU significantly shortened the vesicular phase, healing time, and duration of pain, and it significantly improved post-herpetic neuralgia.

A 1981 trial of 46 shingles patients also confirmed the benefit of DMSO and IDU.16

DMSO and Bacterial Infections

DMSO has five key properties that make it effective in treating bacterial infections:

1. Increased bacterial membrane permeability — DMSO enhances bacterial membrane permeability,17 making bacteria more vulnerable to antibiotics, especially those targeting internal structures (e.g., penicillin). This is crucial for treating infections like tuberculosis, which has a tough outer barrier.

2. Direct bacterial breakdown — DMSO can dissolve bacteria, causing their contents to leak out and effectively neutralizing them.

3. Disruption of bacterial function — DMSO interferes with bacterial metabolism by blocking the production of essential membrane proteins, as shown in studies with E. coli.18

4. Improved circulation — DMSO enhances blood flow,19 which helps combat chronic infections often caused by impaired circulation.

5. Protection against bacterial toxins — DMSO mitigates the harmful effects of bacterial toxins, protecting cells from stress.

DMSO also enhances the immune response,20 contrary to concerns about immune suppression, and has been shown to increase resistance to infections like typhus.21

Common Microbes

DMSO has been extensively tested against common infectious bacteria (e.g., staph, strep, E. coli, pseudomonas), both by itself and in combination with antimicrobial therapies.

After a 196422 study showed DMSO inhibited the growth of bacteria, a 1967 study tested it against various microorganisms, and found at sufficient concentrations that DMSO caused those organisms to dissolve into a sediment.23

dmso bacteriostatic bactericidal effect

A 1969 study24 found that 75% DMSO was bactericidal (mainly by causing their internal contents to leak out), while 15% was sufficient to stop bacterial growth.

dmso e coli

DMSO and Head Infections

Since DMSO is effective in eliminating many common microbial infections, it has shown great promise in ENT (ears, nose, and throat) medicine, as many of those diseases result from infections with common bacteria and the inflammatory response to them (particularly since it is often challenging to get antibiotics to the site of the infection).

Much of this was demonstrated in the 1967 publication25 by an ENT doctor who observed that DMSO would often significantly calm inflammation from an infection in the head (including severe ones that were difficult to treat with antibiotics). He compiled all of his cases26 here:

dmso summary of cases

Eye infections — DMSO can treat various eye conditions, including macular degeneration and eyelid inflammation. In a 1976 study,27 it was combined with antibiotics to successfully treat eye infections. Additionally, DMSO can resolve pink eye after just a few applications.28

Sinusitis — DMSO helps open blocked nostrils quickly by reducing swelling and promoting tissue healing.29 Studies have shown DMSO significantly alleviates sinusitis symptoms, including one 1967 study30 where most patients had excellent results. It also enhances the effectiveness of antibiotics in treating rhinoscleroma,31 a rare nasal infection.

Dentistry — DMSO is used in dentistry as a mouthwash, relieving gum pain32 and preventing bleeding. It can alleviate toothache pain and reduce swelling after dental procedures.33 Dentists have found it effective for treating infections and saving loose teeth from periodontitis.34 Many studies35 show DMSO helps improve gum health, treat pulpitis,36 and accelerate healing after tooth extractions.37

Tuberculosis

Despite over a century of work, Tuberculosis remains the world’s most deadly microbe (e.g., in 2023, it was estimated38 to have killed 1.25 million people). This is mainly due to this tiny bacteria’s unique characteristics and high aptitude for developing antibiotic resistance.

Because of this, once the early DMSO researchers realized that DMSO could remove antibiotic resistance, their focus immediately went to tuberculosis. In turn, many lab studies39 have demonstrated DMSO’s utility for this challenging infection which has been corroborated in humans:

A 1969 study40 of 32, 14 showed an absence of tuberculosis secretion and most showed improvement (e.g., reduced endobronchitis, perifocal infiltration and lung tissue destruction).

A 1980 study41 used DMSO to treat children with pulmonary tuberculosis.

A 1991 study42 found nebulized DMSO mixed with rifampin over 1 to 2 months was an effective treatment for 148 pulmonary tuberculosis and 18 obstructive bronchitis patients (e.g., it healed the destructive cavities caused by tuberculosis).

Bacterial Toxins

One of the primary reasons bacterial infections sicken and kill is because of the toxins they release. DMSO in turn, has been repeatedly shown to mitigate this. For example:

DMSO has been shown43 to protect the duodenum from H. pylori induced chronic ulcers.

In rats, DMSO was shown44 to create a dose dependent reduction in the fluid secretion and mucosal permeability triggered by C. difficile’s toxin (with its maximum inhibition occurring at a 1% concentration). Given how common C. difficile colitis is, this application of DMSO has great promise.

DMSO was shown to protect cells45 from the shigella bacteria’s toxin46 (which causes severe diarrhea and bloody stools).

Endotoxaemia occurs in response to bacterial lipopolysaccharide (LPS) entering the bloodstream. A 2008 study of 18 horses47 found DMSO reduced the fevers that followed artificially induced endotoxemia, suggesting DMSO’s utility in treating sepsis, particularly since, DMSO can protect cells48 from the damage LPS causes.

Note: One of the most important characteristics the early adopters of ultraviolet blood irradiation recognized about it was that UVBI could effectively neutralize toxins in the bloodstream (a property that saved a significant number of lives).

Challenging Infections

DMSO has shown promise for many other challenging infections:

Sepsis — DMSO has proven effective in treating septic complications, especially in heart attack survivors. A 1982 study49 showed its success even against antibiotic-resistant bacteria. In 1984 a Russian study50 confirmed DMSO accelerated recovery in critically ill septic patients, with one case of bladder infection improving after using DMSO.

Note: One author cited51 a case of a septic patient with a severe bladder infection who did not respond to antibiotics but recovered once he began taking one teaspoon of DMSO three times a day.

Lung infections — DMSO has treated chronic lung infections, with a 1975 study52 showing rapid recovery in infants with severe respiratory diseases when combined with antibiotics. A 2020 study53 reported that DMSO, combined with ceftriaxone, helped 31 lung abscess patients fully recover without recurrence.

Note: DMSO has also been repeatedly shown54 to effectively treat acute respiratory distress syndrome, a challenging lung condition that frequently follows severe infections and often requires ventilation.

Abdominal infections — DMSO, combined with antibiotics, has effectively treated peritonitis55 and abdominal abscesses.56 It helps concentrate antibiotics in the abdomen,57 providing extended treatment duration, especially for peritonitis, a fatal condition.
Meningitis

  • A 1978 study58 found DMSO was an effective treatment for meningococcal infections.
  • A 1987 study59 used DMSO combined with a nuclease to treat meningitis or meningoencephalitis caused by an acute viral respiratory infection.
Osteomyelitis — DMSO has shown significant results in treating bone infections.60 Studies have found that combining DMSO with antibiotics and other therapies like hyperbaric oxygen speeds up recovery and reduces bone damage in both acute and chronic osteomyelitis.61,62,63,64,65,66
Orchitis and epididymitis — In 1986, a Russian physician reported these conditions have an excellent response to DMSO.67
Cancer and autoimmunity — DMSO has been observed to eliminate the unusual bacteria associated with many cancers and autoimmune diseases, which may in part explain its utility for those conditions.

Note: A wealth of evidence also supports DMSO’s use in a variety of challenging veterinary infections.68

Surgery

Three of the major issues encountered in surgery are:

  • Surgical wounds (or burns) become infected before they seal and heal.
  • Infections deep within the body need to be cut open so the infection can be drained or removed (or have antibiotics directly applied to it).
  • Infected tissues must be removed (e.g., amputated) because the infection within them can’t be reached or addressed.

Fortunately, DMSO’s is uniquely suited to address each of these. For example, in this article, I discussed how many studies and reader testimonials show DMSO is a remarkable therapy for burns and wound healing, and here I reviewed the wealth of evidence that DMSO is a highly effective therapy for surgical scar healing.

Likewise, DMSO makes reaching a deep infection within the body possible without surgery. Numerous studies, in turn, demonstrate that DMSO can prevent and treat those infections:

A 1969 case report69 highlighted a patient with a chronic fungal infection (that has high resistance to antifungals) who declined amputation in favor of antifungals dissolved in DMSO which saved his foot.

Note: There are many other cases of DMSO curing a chronic infection that had required amputation.70

A 1978 surgical study71 used DMSO in combination with antibiotics to treat inflammatory infiltrates.
A 1984 study72 used DMSO to treat surgical wound infections.
A 1985 study73 found that injecting DMSO after severe mechanical trauma reduces the risks of a subsequent infection, while a 1984 study74 found that DMSO plus antibiotics prevent open wounds in the hands from developing purulent infections.
A 1990 study75 of 33 patients with phlegmons (inflamed areas under the skin) throughout the body found that a dressing with DMSO and silver nitrate, when compared to those receiving standard treatments, reduced the time required to begin a surgical repair by 2 to 2.5 times.
In 1998, Russian physicians reported that they routinely apply DMSO to surgical wounds as it accelerates healing and provides general infection control.76

Fungal Infections

A 2013 study77 used DMSO and antifungal agents on six different Candida species. It found 0.5% to 1% DMSO had an antifungal effect, but the inhibitory effect (with or without concurrent antifungals) varied significantly.

DMSO can also effectively bring antifungals to many parts of the body. DMSO for instance was shown78 to significantly increase the amount of ketoconazole that enters the brain and can transport griseofulvin79 through the skin (which in a 1974 study80 was used to successfully treat ringworm). Additionally:

  • A 1965 study81 found DMSO was an effective treatment for ringworm and athlete’s foot, especially when combined with an antifungal.
  • A 1977 study82 found DMSO (in combination with lidase) was a highly effective treatment for actinomycosis of the face and neck.
  • A 1997 study83 found DMSO mixed with itraconazole treated fungal infections in horse corneas.

Parasites

There is also some data on how DMSO can treat parasites (e.g., 3% DMSO has been shown to significantly inhibit the growth of Trypanosoma cruzi,84 which causes Chagas disease). However, its primary value is bringing an antiparasitic medication to the region of infection (as parasites can often burrow quite deep into the tissues).

For example, two different 1966 studies (this study85 and this 25 person RCT86) found that DMSO plus an antiparasitic (e.g., 2% topical thiabendazole in 90% DMSO) was an effective treatment for hookworm infections in the skin. DMSO can also be combined with antiparasitic medications to reach challenging parasitic infections deep within the body. For example, a 1984 case report87 discussed DMSO treating a complex amoeba infection of the liver.

Conclusion

Many who’ve worked with DMSO believe it should be routinely utilized for severe infections, particularly those not responding to antibiotic therapy. Fortunately, we are in a unique moment where these forgotten sides of medicine finally have a chance to see the light of day.

Thus, I sincerely hope articles like these can begin to shift the medical system towards adopting a more sophisticated approach to infectious diseases that can help patients struggling with challenging infections.

Author’s Note: This is an abridged version of a longer article that goes into greater detail on the points discussed here and provides guidance for personal DMSO use (e.g., dosing, therapeutic precautions and where to obtain it) along with other natural approaches we’ve also found help many of those conditions (e.g., herpes and shingles). That article can be read here.

A Note from Dr. Mercola About the Author

A Midwestern Doctor (AMD) is a board-certified physician from the Midwest and a longtime reader of Mercola.com. I appreciate AMD’s exceptional insight on a wide range of topics and am grateful to share it. I also respect AMD’s desire to remain anonymous since AMD is still on the front lines treating patients. To find more of AMD’s work, be sure to check out The Forgotten Side of Medicine on Substack.

 

– Sources and References

ALARMING new evidence suggests monkeypox is cover-up for COVID jab-induced adverse effect

Reproduced from original article:
https://www.naturalhealth365.com/alarming-new-evidence-suggests-monkeypox-is-cover-up-for-covid-jab-induced-adverse-effect.html


by:  | August 7, 2022

monkeypox-is-covid-shot-adverse-effect(NaturalHealth365)  Can you imagine a dystopian world in which zoonotic viruses are used to conceal problems resulting from vaxing people against highly survivable communicable diseases?  Take a moment to consider a world where such injections are necessary for employment, education, and other social participation.  It appears as though this dystopian reality has quickly become the world we live in.  New evidence makes it appear as though monkeypox is a cover-up for immune deficiency syndrome resulting from the jab.

If the evidence proves accurate, the histrionics concerning monkeypox are unjustified as this isn’t the first monkeypox virus to spread across first-world nations.  Rather, it appears as though we are viewing a cover-up of damage inflicted on the immune systems of those who were provided with the coronavirus vax.  This damage may be extensive to the point that it resembles Acquired Immunodeficiency Syndrome.

What are the origins of the monkeypox virus?

Rewind to the 1970s, and monkeypox was a big deal as this was the point in time when the virus was first identified in human beings.  The virus was initially identified in people in the Democratic Republic of the Congo.  Since then, human cases of monkeypox have been reported in nearly a dozen African nations.

In reality, monkeypox disease is incredibly rare, has rarely been seen outside of Africa, and indeed never appeared in multiple countries outside of Africa simultaneously.  This time around, however, we are told of new monkeypox cases in the United States, Europe, Canada, and elsewhere all in unison.

Coincidence?  Symptoms of alleged monkeypox similar to listed COVID jab adverse effect

The symptoms of monkeypox are similar to those of herpes.  However, perhaps what is most shocking is that herpes is considered a documented COVID shot adverse event by Pfizer.  Though this revelation was made public in the documents published by the FDA earlier this year, the mainstream media didn’t give it much credence.

Herpes symptoms typically include:

  • Mild redness and tingling
  • Swollen lymph glands
  • Fever
  • Lesions similar to blisters that become sores

It is becoming increasingly clear that the symptoms of the COVID-19 jab manifest in a form similar to those of monkeypox and herpes, prompting concerned individuals to obtain the monkeypox vaccination when the truth is it is the jab itself that is the root cause of the problems.

Here is how the COVID shot affects the immune system

Turn on the nightly news, and you’ll hear word of variant-specific boosters.  The federal government now suggests that Americans receive separate booster shots specific to each unique coronavirus variant.  Furthermore, these variant-specific booster shots are in addition to the initial two boosters provided in previous months.  Add up all the coronavirus shots by the end of the year, and the total might be in the double digits.  It is only fair to question whether such a litany of shots will negatively impact the human immune system.

Theoretically, the coronavirus vax is designed to train the immune system to recognize the coronavirus spike protein of the original strain by turning your cells into a spike protein factory, spurring the generation of antibodies for potential use down the line.  The immune system is then tasked with battling the virus, yet the vax efficacy ultimately dissipates.

Regardless of the supposed vax mechanism of action, one need not look any further than the data about coronavirus deaths based on vax status to realize that immune deficiency syndrome acquired through the vax has the potential to cause the activation of inactive herpes.

Stay tuned as more details about the possible links between the coronavirus jab and other health problems are revealed in the months ahead.

Sources for this article include:

Assets.publishing.service.gov.uk
Expose-News.com